NocII

发表于2023年10月23日由Whatman官网

NocII;

NocII 是一种孤儿神经肽，可刺激小鼠运动。

NocII Chemical Structure

CAS No. : 188119-47-3

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250 mg	;	询价	;
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生物活性

NocII is an orphan neuropeptide which stimulates locomotion in mice^[1].

体外研究
(In Vitro)

NocII is a heptadecapeptide whose sequence lies immediately downstream of nociception^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

2081.37

Formula

C₉₂H₁₄₁N₂₃O₂₈S₂

CAS 号

188119-47-3

Sequence

Phe-Ser-Glu-Phe-Met-Arg-Gln-Tyr-Leu-Val-Leu-Ser-Met-Gln-Ser-Ser-Gln

Sequence Shortening

FSEFMRQYLVLSMQSSQ

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility

In Vitro:;

H₂O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

;	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3.;;Recommended solution:

Overall charge of peptide	Details
Negative (lt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, add NH₄OH (lt;50 μL). 3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

参考文献

[1]. S Florin, et al. Orphan neuropeptide NocII, a putative pronociceptin maturation product, stimulates locomotion in mice. Neuroreport. 1997 Feb 10;8(3):705-7.

NocII TFA

发表于2023年10月10日由Whatman官网

NocII TFA;

NocII TFA 是一种孤儿神经肽，可刺激小鼠运动。

NocII TFA Chemical Structure

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;