标签归档：omiganan

Omiganan

发表于由

Omiganan; 纯度: 99.55%

Omiganan 是一种阳离子抗菌肽。Omiganan 作为吲哚啶的类似物，对革兰氏阳性菌和革兰氏阴性菌均有抑制作用，对念珠菌也有抑制作用。Omiganan 可以用于酒精鼻和痤疮的研究。

Omigananamp;;

Omiganan Chemical Structure

CAS No. : 204248-78-2

规格 价格 是否有货 数量
5 mg ￥1500 In-stock
10 mg ￥2500 In-stock
25 mg ￥5500 In-stock
50 mg ￥9500 In-stock
100 mg ￥15500 In-stock
200 mg ; 询价 ;
500 mg ; 询价 ;

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Omiganan 相关产品

bull;相关化合物库:

  • Drug Repurposing Compound Library Plus
  • Clinical Compound Library Plus
  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Omiganan is a cationic antimicrobial peptide. Omiganan as an analogue of indolicidin shows activity against gram-positive and gram-negative bacteria but also Candida spp. isolates. Omiganan can be used for the research of alcohol nose and acne[1][2].

体内研究
(In Vivo)

Omiganan results in a statistically significantly reduction in bacterial counts. omiganan reduces the bacterial counts by 3.8 (S. aureus), 2.2 (S. epidermidis) and 2.3 (C. albicans) log10 CFU/site. Omiganan has rapid bactericidal and fungicidal properties and significant dose-dependent activity against a broad spectrum of infected organisms[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial

分子量

1779.15

Formula

C90H127N27O12
CAS 号

204248-78-2
Sequence Shortening

ILRWPWWPWRRK-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Protect from light, stored under nitrogen

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light, stored under nitrogen)
参考文献

  • [1]. Faccone D, et al. Antimicrobial activity of de novo designed cationic peptides against multi-resistant clinical isolates. Eur J Med Chem. 2014;71:31-35.

    [2]. Rubinchik E, et al. Antimicrobial and antifungal activities of a novel cationic antimicrobial peptide, omiganan, in experimental skin colonisation models. Int J Antimicrob Agents. 2009;34(5):457-461.

Omiganan-FITC(Synonyms: 奥米加南-FITC)

发表于由

Omiganan-FITC;(Synonyms: 奥米加南-FITC)

Omiganan-FITC 是由 Omiganan 和 FITC 组成的肽-FITC 复合物。Omiganan 是一种抗细菌和真菌的阳离子肽，可作为一种局部凝胶用于预防导管相关感染。FITC 是荧光素的衍生物，用于标记伯胺。

Omiganan-FITCamp;;(Synonyms: 奥米加南-FITC)

Omiganan-FITC Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Omiganan-FITC is a peptide-FITC complex composed of Omiganan and a FITC. Omiganan is a bactericidal and fungicidal cationic peptide being developed as a topical gel for prevention of catheter-associated infections. FITC is a derivative of fluorescein for the labeling of amines[1].

Sequence

FITC-Ile-Leu-Arg-Trp-Pro-Trp-Trp-Pro-Trp-Arg-Arg-Lys-NH2
Sequence Shortening

FITC-ILRWPWWPWRRK-NH2-FITC
中文名称

奥米加南-FITC
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Thomas R Fritsche, et al. Antimicrobial Activity of Omiganan Pentahydrochloride Against Contemporary Fungal Pathogens Responsible for Catheter-Associated Infections. Antimicrob Agents Chemother. 2008 Mar;52(3):1187-9.

Omiganan-FITC TFA

发表于由

Omiganan-FITC TFA;

Omiganan-FITC TFA 是由 Omiganan 和 FITC 组成的肽-FITC 复合体。Omiganan 是一种抗细菌和真菌的阳离子肽，可作为一种局部凝胶用于预防导管相关感染。

Omiganan-FITC TFAamp;;

Omiganan-FITC TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Omiganan-FITC TFA is a peptide-FITC complex composed of Omiganan and a FITC. Omiganan is a bactericidal and fungicidal cationic peptide being developed as a topical gel for prevention of catheter-associated infections[1].

Sequence

FITC-Ile-Leu-Arg-Trp-Pro-Trp-Trp-Pro-Trp-Arg-Arg-Lys-NH2
Sequence Shortening

FITC-ILRWPWWPWRRK-NH2-FITC
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Thomas R Fritsche, et al. Antimicrobial Activity of Omiganan Pentahydrochloride Against Contemporary Fungal Pathogens Responsible for Catheter-Associated Infections. Antimicrob Agents Chemother. 2008 Mar;52(3):1187-9.