EGFRvIII peptide (PEPvIII)

EGFRvIII peptide (PEPvIII);

EGFRvIII peptide (PEPvIII) 是一种肿瘤特异性突变,广泛表达于多形性胶质母细胞瘤 (GBM) 和其他肿瘤中,其表达增强了肿瘤发生率。EGFRvIII peptide (PEPvIII) 是抗肿瘤免疫的一个真正的特异性靶点。

EGFRvIII peptide (PEPvIII)amp;;

EGFRvIII peptide (PEPvIII) Chemical Structure

CAS No. : 129112-17-0

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生物活性

EGFRvIII peptide (PEPvIII) is a tumor-specific mutation that is widely expressed in glioblastoma multiforme (GBM) and other neoplasms and its expression enhances tumorigenicity. EGFRvIII peptide represents a truly tumor-specific target for antitumor immunotherapy[1].

分子量

1634.81

Formula

C70H111N19O24S

CAS 号

129112-17-0

Sequence Shortening

LEEKKGNYVVTDHC

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Schmittling RJ, et al. Detection of humoral response in patients with glioblastoma receiving EGFRvIII-KLH vaccines. J Immunol Methods. 2008 Nov 30;339(1):74-81.