Fc (LALA-PG)-KIH (human) IgG1 Control (rec.) 品牌:Adipogen


Fc (LALA-PG)-KIH (human) IgG1 Control (rec.)

品牌:Adipogen
CAS No.:
储存条件:-20°C
纯度:>95% (SDS-PAGE)
产品编号

(生产商编号)

等级 规格 运输包装 零售价(RMB) 库存情况 参考值

AG-35B-0018-C050

50 µg 3,600.00


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动,恕不另行通知,确切详情请联系上海金畔生物科技有限公司。

Fc (LALA-PG)-KIH (human):GDF15 (mouse) (rec.) 品牌:Adipogen


Fc (LALA-PG)-KIH (human):GDF15 (mouse) (rec.)

品牌:Adipogen
CAS No.:
储存条件:-20°C
纯度:>95% (SDS-PAGE)
产品编号

(生产商编号)

等级 规格 运输包装 零售价(RMB) 库存情况 参考值

AG-40B-0245-C050

50 µg 4,800.00


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动,恕不另行通知,确切详情请联系上海金畔生物科技有限公司。

Fc (LALA-PG)-KIH (human):Irisin (monomeric) (rec.) 品牌:Adipogen


Fc (LALA-PG)-KIH (human):Irisin (monomeric) (rec.)

品牌:Adipogen
CAS No.:
储存条件:-20°C
纯度:>95% (SDS-PAGE)
产品编号

(生产商编号)

等级 规格 运输包装 零售价(RMB) 库存情况 参考值

AG-40B-0246-C050

50 µg 4,800.00


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动,恕不另行通知,确切详情请联系上海金畔生物科技有限公司。

PG106 TFA

PG106 TFA; 纯度: 99.15%

PG106 TFA 是一种有效的、选择性的 hMC3 receptor 拮抗剂 (IC50= 210 nM),对 hMC4 受体(EC50=9900 nM) 和 hMC5 受体无活性。

PG106 TFAamp;;

PG106 TFA Chemical Structure

规格 价格 是否有货 数量
1 mg ¥1900 In-stock
5 mg ¥6700 In-stock
10 mg ¥11000 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

* Please select Quantity before adding items.

PG106 TFA 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • GPCR/G Protein Compound Library
  • Neuronal Signaling Compound Library
  • Peptide Library

生物活性

PG106 TFA is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC50= 210 nM) and has noactivity at hMC4 receptors (EC50=9900 nM) and hMC5 receptor[1].

IC50 Target

IC50: 210 nM (hMC3 receptor)
EC50: 9900 nM (hMC4 receptor)[1]

分子量

1122.20

Formula

C53H70F3N13O11

Sequence Shortening

Ac-{Nle}-D-{Bal}-{D-Nal}-RWK-NH2 (Lactam bridge:Asp2-Lys7)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro:;

DMSO : 25 mg/mL (22.28 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.8911 mL 4.4555 mL 8.9111 mL
5 mM 0.1782 mL 0.8911 mL 1.7822 mL
10 mM 0.0891 mL 0.4456 mL 0.8911 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂:;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.5 mg/mL (2.23 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (2.23 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂:;10% DMSO ;; 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (2.23 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (2.23 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中,混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中,再用生理盐水定容至 10 mL,完全溶解,澄清透明
  • 3.

    请依序添加每种溶剂:;10% DMSO ;; 90% corn oil

    Solubility: ≥ 2.5 mg/mL (2.23 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (2.23 mM,饱和度未知) 的澄清溶液,此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中,混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。
参考文献
  • [1]. Paolo Grieco, et al. Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. Peptides

日本 Advantec 东洋 PG-60 复合滤纸PG-60

日本 Advantec 东洋 PG-60 复合滤纸

简要描述:

  • PTFE涂层:疏水性和不受湿度影响

    用途

  • 空气污染分析

  • 空气灰尘分析

    注意:不可以使用在液体过滤

    订货资料
    目录号 – 描述

    36661021  – PG60/21mm直径复合滤纸,100张/盒
    36661024 –  PG60/24mm直径复合滤纸,100张/盒
    36661025 –  PG60/25mm直径复合滤纸,100张/盒
    36661026 –  PG60/26mm直径复合滤纸,100张/盒
    36661037 –  PG60/37mm直径复合滤纸,100张/盒
    36661045 –  PG60/45mm直径复合滤纸,100张/盒
    36661047 –  PG60/47mm直径复合滤纸,100张/盒
    36661055 –  PG60/55mm直径复合滤纸,100张/盒
    36661070 –  PG60/70mm直径复合滤纸,100张/盒
    36661090 –  PG60/90mm直径复合滤纸,50张/盒
    A3666004 –  PG60/102mm直径复合滤纸,50张/盒
    36661110 –  PG60/110mm直径复合滤纸,50张/盒
    36661125 –  PG60/125mm直径复合滤纸,50张/盒
    36661150 –  PG60/150mm直径复合滤纸,50张/盒
    36663203 –  PG60/203mmx254mm复合滤纸,50张/盒
    36663300 –  PG60/300mmx300mm复合滤纸,10张/盒

    ****其他尺寸请与我们****

PG-931 TFA

PG-931 TFA;

PG-931 TFA 是 SHU 9119 (HY-P0227) 的类似物。PG-931 TFA 是一种强效的黑素皮质素 4 (MC4) 受体(IC50=0.58 nM) 激动剂,比 hMC3R (IC50=55 nM) 或 hMC5R (IC50=2.4 nM)更具选择性。PG-931 TFA 在动物实验模型中,可逆转出血休克,防止体内多器官损伤。

PG-931 TFAamp;;

PG-931 TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

PG-931 TFA, an analog of SHU 9119 (HY-P0227), is a potent melanocortin 4 (MC4) receptor (IC50=0.58 nM) agonist and is more selective than for the hMC3R (IC50=55 nM) or the hMC5R(IC50=2.4 nM). PG-931 TFA can reverse haemorrhagic shock and prevent multiple organ damage in vivo[2].

体内研究
(In Vivo)

PG-931 (intravenous injection; 13-108 nmol/kg; single dose) produces a dose-dependent restoration of cardiovascular and respiratory functions, and improved survival in Wistar rats with haemorrhagic shock[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Wistar rats[1]
Dosage: 13-108 nmol/kg
Administration: Intravenous injection; single dose
Result: Exhibits an anti-shock effect occurred at nanomolar doses.

分子量

1294.42

Formula

C61H86F3N15O13

Sequence Shortening

Ac-{Nle}-DP-{D-Phe}-RWKPV-NH2 (Lactam bridge:Asp2-Lys7)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. D Giuliani, et al. Selective melanocortin MC4 receptor agonists reverse haemorrhagic shock and prevent multiple organ damage. Br J Pharmacol

    [2]. P Grieco, et al. Extensive structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. J Pept Res

PG-60-日本 Advantec 东洋 PG-60 复合滤纸

产品型号PG-60

品       牌ADVANTEC

厂商性质代理商

产品简介

日本 Advantec 东洋 PG-60 复合滤纸 特别为测量空气中灰尘浓度设计,PTFE涂层:疏水性和不受湿度影响

详情介绍

  • 复合滤纸 PG-60 特别为测量空气中灰尘浓度设计

  • PTFE涂层:疏水性和不受湿度影响

    用途

  • 空气污染分析

  • 空气灰尘分析

    注意:不可以使用在液体过滤

    订货资料
    目录号 – 描述

    36661021  – PG60/21mm直径复合滤纸,100张/盒
    36661024 –  PG60/24mm直径复合滤纸,100张/盒
    36661025 –  PG60/25mm直径复合滤纸,100张/盒
    36661026 –  PG60/26mm直径复合滤纸,100张/盒
    36661037 –  PG60/37mm直径复合滤纸,100张/盒
    36661045 –  PG60/45mm直径复合滤纸,100张/盒
    36661047 –  PG60/47mm直径复合滤纸,100张/盒
    36661055 –  PG60/55mm直径复合滤纸,100张/盒
    36661070 –  PG60/70mm直径复合滤纸,100张/盒
    36661090 –  PG60/90mm直径复合滤纸,50张/盒
    A3666004 –  PG60/102mm直径复合滤纸,50张/盒
    36661110 –  PG60/110mm直径复合滤纸,50张/盒
    36661125 –  PG60/125mm直径复合滤纸,50张/盒
    36661150 –  PG60/150mm直径复合滤纸,50张/盒
    36663203 –  PG60/203mmx254mm复合滤纸,50张/盒
    36663300 –  PG60/300mmx300mm复合滤纸,10张/盒

    ****其他尺寸请与我们****

PG-931

PG-931;

PG-931 是 SHU 9119 (HY-P0227) 的类似物。PG-931 是一种强效的黑素皮质素 4 (MC4) 受体 (IC50=0.58 nM) 激动剂,比 hMC3R (IC50=55 nM) 或 hMC5R (IC50=2.4 nM) 更具选择性。PG-931 在动物实验模型中,可逆转出血休克,防止体内多器官损伤。

PG-931amp;;

PG-931 Chemical Structure

CAS No. : 667430-81-1

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

PG-931, an analog of SHU 9119 (HY-P0227), is a potent melanocortin 4 (MC4) receptor (IC50=0.58 nM) agonist and is more selective than for the hMC3R (IC50=55 nM) or the hMC5R (IC50=2.4 nM). PG-931 can reverse haemorrhagic shock and prevent multiple organ damage in vivo[2].

IC50 Target

IC50: 0.58 nM (melanocortin 4 receptor)
IC50: 2.4 nM (melanocortin 5 receptor)
IC50: 55 nM (melanocortin 3 receptor)[1]

体内研究
(In Vivo)

PG-931 (intravenous injection; 13-108 nmol/kg; single dose) produces a dose-dependent restoration of cardiovascular and respiratory functions, and improved survival in Wistar rats with haemorrhagic shock[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Wistar rats[2]
Dosage: 13-108 nmol/kg
Administration: Intravenous injection; single dose
Result: Exhibitd an anti-shock effect occurred at nanomolar doses.

分子量

1180.40

Formula

C59H85N15O11

CAS 号

667430-81-1

Sequence Shortening

Ac-{Nle}-DP-{D-Phe}-RWKPV-NH2 (Lactam bridge:Asp2-Lys7)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. D Giuliani, et al. Selective melanocortin MC4 receptor agonists reverse haemorrhagic shock and prevent multiple organ damage. Br J Pharmacol

    [2]. P Grieco, et al. Extensive structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. J Pept Res

PG106

PG106;

PG106 是一种有效的、选择性的 hMC3 receptor 拮抗剂 (IC50= 210 nM),对 hMC4 受体(EC50=9900 nM) 和 hMC5 受体无活性。

PG106amp;;

PG106 Chemical Structure

CAS No. : 944111-22-2

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

PG106 的其他形式现货产品:

PG106 TFA

生物活性

PG106 is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC50=210 nM) and has noactivity at hMC4 receptors (EC50=9900 nM) and hMC5 receptor[1].

IC50 Target

IC50: 210 nM (hMC3 receptor)
EC50: 9900 nM (hMC4 receptor)[1]

分子量

1008.18

Formula

C51H69N13O9

CAS 号

944111-22-2

Sequence Shortening

Ac-{Nle}-D-{Bal}-{D-Nal}-RWK-NH2 (Lactam bridge:Asp2-Lys7)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Paolo Grieco, et al. Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. Peptides

日本东洋直径110mm PG-60复合滤纸 PG60/110mm

日本东洋直径110mm PG-60复合滤纸

简要描述:

日本东洋直径110mm PG-60复合滤纸

产品简介

日本 Advantec 东洋 PG-60 复合滤纸 特别为测量空气中灰尘浓度设计,PTFE涂层:疏水性和不受湿度影响

详细介绍

复合滤纸 PG-60 特别为测量空气中灰尘浓度设计

PTFE涂层:疏水性和不受湿度影响

用途

空气污染分析

空气灰尘分析注意:不可以使用在液体过滤

日本东洋直径110mm PG-60复合滤纸 订货资料

目录号 – 描述

36661021  – PG60/21mm直径复合滤纸,100张/盒

36661024 –  PG60/24mm直径复合滤纸,100张/盒

36661025 –  PG60/25mm直径复合滤纸,100张/盒

36661026 –  PG60/26mm直径复合滤纸,100张/盒

36661037 –  PG60/37mm直径复合滤纸,100张/盒

36661045 –  PG60/45mm直径复合滤纸,100张/盒

36661047 –  PG60/47mm直径复合滤纸,100张/盒

36661055 –  PG60/55mm直径复合滤纸,100张/盒

36661070 –  PG60/70mm直径复合滤纸,100张/盒

36661082  – PG60/82mm直径复合滤纸,50张/盒

36661090 –  PG60/90mm直径复合滤纸,50张/盒

A3666004 –  PG60/102mm直径复合滤纸,50张/盒

36661110 –  PG60/110mm直径复合滤纸,50张/盒

36661125 –  PG60/125mm直径复合滤纸,50张/盒

36661150 –  PG60/150mm直径复合滤纸,50张/盒

36663203 –  PG60/203mmx254mm复合滤纸,50张/盒

36663300 –  PG60/300mmx300mm复合滤纸,10张/盒