VIP(Guinea pig)(Synonyms: Vasoactive Intestinal Peptide, guinea pig)

VIP(Guinea pig);(Synonyms: Vasoactive Intestinal Peptide, guinea pig)

VIP Guinea pig (Vasoactive intestinal peptide) 是一种营养和有丝分裂因子,可刺激胚胎生长。VIP Guinea pig 是一种简单的胃肠激素,具有神经递质的功能。

VIP(Guinea pig)amp;;(Synonyms: Vasoactive Intestinal Peptide, guinea pig)

VIP(Guinea pig) Chemical Structure

CAS No. : 96886-24-7

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

VIP Guinea pig (Vasoactive intestinal peptide), a trophic and mitogenic factor, stimulates growth in whole cultured embryos. VIP Guinea pig functions as a simple gastrointestinal hormone and suggest a possible neurotransmitter function[1][2].

体外研究
(In Vitro)

Vasoactive intestinal peptide (10(-7)M) shortened S phase and G1 phase of neuroepithelial cells by 50% (4.8-2.4 h) and 58% (1.9-0.8 h), respectively, compared with controls[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

3344.86

Formula

C147H239N43O42S2

CAS 号

96886-24-7

Sequence

His-Ser-Asp-Ala-Leu-Phe-Thr-Asp-Thr-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Met-Lys-Lys-Tyr-Leu-Asn-Ser-Val-Leu-Asn-NH2

Sequence Shortening

HSDALFTDTYTRLRKQMAMKKYLNSVLN-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. P Gressens, et al. Vasoactive intestinal peptide shortens both G1 and S phases of neural cell cycle in whole postimplantation cultured mouse embryos. Eur J Neurosci. 1998 May;10(5):1734-42.

    [2]. M G Bryant, et al. Possible dual role for vasoactive intestinal peptide as gastrointestinal hormone and neurotransmitter substance. Lancet. 1976 May 8;1(7967):991-3.

Beta-defensin 1, pig TFA(Synonyms: 猪 β-防御素1 三氟乙酸盐)

Beta-defensin 1, pig TFA;(Synonyms: 猪 β-防御素1 三氟乙酸盐)

Beta-defensin 1, pig TFA 是主要在猪舌黏膜中发现的一种抗菌肽。Beta-defensin 1, pig TFA 对大肠杆菌,鼠伤寒沙门氏菌,单核细胞增生性李斯特菌,金黄色葡萄球菌,百日咳博德特氏菌和白色念珠菌等细菌具有活性。

Beta-defensin 1, pig TFAamp;;(Synonyms: 猪 β-防御素1 三氟乙酸盐)

Beta-defensin 1, pig TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Beta-defensin 1, pig TFA is an antimicrobial peptide found primarily in tongue mucosa of pig. Beta-defensin 1, pig TFA is active against bacteria such as Escherichia coli, Salmonella typhimurium, Listeria monocytogenes, Staphylococcus aureus, Bordetella pertussis and Candida albicans[1][2].

IC50 Target

Bacterial[1]

体外研究
(In Vitro)

Expression of beta-defensin (pBD-1) mRNA increased from the proximal to the distal part of the intestine whereas pBD-2 expression decreased. The main gene expression sites for pBD-2 are kidney and liver, whereas pBD-1 is mainly expressed in tongue[1].
An eight-fold increase in pBD-1 mRNA expression is observed upon S. typhimurium infection in the porcine intestinal cell line IPEC J2[1].
Porcine beta-defensin 1 (pBD-1) also has immunomodulatory activity in porcine peripheral blood mononuclear cells and lymph node cells[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Resistance against respiratory infection with B. pertussis in older piglets is associated with the presence of Porcine beta-defensin 1 (pBD-1) in the upper respiratory tract. Furthermore, treatment with pBD-1 conferred complete protection of newborn piglets from intrapulmonary infection with B. pertussis[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

7524.92

Formula

C323H535N92F3O92S9

Sequence

Met-Arg-Ala-Leu-Cys-Leu-Leu-Leu-Leu-Thr-Val-Cys-Leu-Leu-Ser-Ser-Gln-Leu-Ala-Ala-Gly-Ile-Asn-Leu-Leu-Thr-Gly-Leu-Gly-Gln-Arg-Ser-Asp-His-Tyr-Ile-Cys-Ala-Lys-Lys-Gly-Gly-Thr-Cys-Asn-Phe-Ser-Pro-Cys-Pro-Leu-Phe-Asn-Arg-Ile-Glu-Gly-Thr-Cys-Tyr-Ser-Gly-Lys-Ala-Lys-Cys-Cys-Ile-Arg

Sequence Shortening

MRALCLLLLTVCLLSSQLAAGINLLTGLGQRSDHYICAKKGGTCNFSPCPLFNRIEGTCYSGKAKCCIR

中文名称

猪 β-防御素1 三氟乙酸盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Edwin J A Veldhuizen , et al. Expression of Beta-Defensins pBD-1 and pBD-2 Along the Small Intestinal Tract of the Pig: Lack of Upregulation in Vivo Upon Salmonella Typhimurium Infection. Mol Immunol. 2007 Jan;44(4):276-83.

    [2]. D R Pruthviraj, et al. Identification of a Novel Single Nucleotide Polymorphism in Porcine Beta-Defensin-1 Gene. Asian-Australas J Anim Sci. 2016 Mar;29(3):315-20.

    [3]. Shokrollah Elahi, et al. The Host Defense Peptide Beta-Defensin 1 Confers Protection Against Bordetella Pertussis in Newborn Piglets. Infect Immun. 2006 Apr;74(4):2338-52.

VIP(Guinea pig) TFA(Synonyms: Vasoactive Intestinal Peptide, guinea pig TFA)

VIP(Guinea pig) TFA;(Synonyms: Vasoactive Intestinal Peptide, guinea pig TFA)

VIP Guinea pig TFA (Vasoactive intestinal peptide) 是一种营养和有丝分裂因子,可刺激胚胎生长。VIP Guinea pig 是一种简单的胃肠激素,具有神经递质的功能。

VIP(Guinea pig) TFAamp;;(Synonyms: Vasoactive Intestinal Peptide, guinea pig TFA)

VIP(Guinea pig) TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

VIP Guinea pig TFA (Vasoactive intestinal peptide), a trophic and mitogenic factor, stimulates growth in whole cultured embryos. VIP Guinea pig functions as a simple gastrointestinal hormone and suggest a possible neurotransmitter function[1][2].

体外研究
(In Vitro)

Vasoactive intestinal peptide (10(-7)M) shortened S phase and G1 phase of neuroepithelial cells by 50% (4.8-2.4 h) and 58% (1.9-0.8 h), respectively, compared with controls[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

3458.88

Formula

C147H239N43O42S2.C2HF3O2

Sequence

His-Ser-Asp-Ala-Leu-Phe-Thr-Asp-Thr-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Met-Lys-Lys-Tyr-Leu-Asn-Ser-Val-Leu-Asn-NH2

Sequence Shortening

HSDALFTDTYTRLRKQMAMKKYLNSVLN-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. P Gressens, et al. Vasoactive intestinal peptide shortens both G1 and S phases of neural cell cycle in whole postimplantation cultured mouse embryos. Eur J Neurosci. 1998 May;10(5):1734-42.

    [2]. M G Bryant, et al. Possible dual role for vasoactive intestinal peptide as gastrointestinal hormone and neurotransmitter substance. Lancet. 1976 May 8;1(7967):991-3.

Beta-defensin 1, pig(Synonyms: 猪 β-防御素1)

Beta-defensin 1, pig;(Synonyms: 猪 β-防御素1)

Beta-defensin 1, pig 是主要在猪舌黏膜中发现的一种抗菌肽。Beta-defensin 1, pig 对大肠杆菌,鼠伤寒沙门氏菌,单核细胞增生性李斯特菌,金黄色葡萄球菌,百日咳博德特氏菌和白色念珠菌等细菌具有活性。

Beta-defensin 1, pigamp;;(Synonyms: 猪 β-防御素1)

Beta-defensin 1, pig Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Beta-defensin 1, pig is an antimicrobial peptide found primarily in tongue mucosa of pig. Beta-defensin 1, pig is active against bacteria such as Escherichia coli, Salmonella typhimurium, Listeria monocytogenes, Staphylococcus aureus, Bordetella pertussis and Candida albicans[1][2].

IC50 Target

Bacterial[1]

体外研究
(In Vitro)

Expression of beta-defensin (pBD-1) mRNA increased from the proximal to the distal part of the intestine whereas pBD-2 expression decreased. The main gene expression sites for pBD-2 are kidney and liver, whereas pBD-1 is mainly expressed in tongue[1].
An eight-fold increase in pBD-1 mRNA expression is observed upon S. typhimurium infection in the porcine intestinal cell line IPEC J2[1].
Porcine beta-defensin 1 (pBD-1) also has immunomodulatory activity in porcine peripheral blood mononuclear cells and lymph node cells[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Resistance against respiratory infection with B. pertussis in older piglets is associated with the presence of Porcine beta-defensin 1 (pBD-1) in the upper respiratory tract. Furthermore, treatment with pBD-1 conferred complete protection of newborn piglets from intrapulmonary infection with B. pertussis[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

7410.90

Formula

C321H534N92O90S9

Sequence

Met-Arg-Ala-Leu-Cys-Leu-Leu-Leu-Leu-Thr-Val-Cys-Leu-Leu-Ser-Ser-Gln-Leu-Ala-Ala-Gly-Ile-Asn-Leu-Leu-Thr-Gly-Leu-Gly-Gln-Arg-Ser-Asp-His-Tyr-Ile-Cys-Ala-Lys-Lys-Gly-Gly-Thr-Cys-Asn-Phe-Ser-Pro-Cys-Pro-Leu-Phe-Asn-Arg-Ile-Glu-Gly-Thr-Cys-Tyr-Ser-Gly-Lys-Ala-Lys-Cys-Cys-Ile-Arg

Sequence Shortening

MRALCLLLLTVCLLSSQLAAGINLLTGLGQRSDHYICAKKGGTCNFSPCPLFNRIEGTCYSGKAKCCIR

中文名称

猪 β-防御素1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Edwin J A Veldhuizen , et al. Expression of Beta-Defensins pBD-1 and pBD-2 Along the Small Intestinal Tract of the Pig: Lack of Upregulation in Vivo Upon Salmonella Typhimurium Infection. Mol Immunol. 2007 Jan;44(4):276-83.

    [2]. D R Pruthviraj, et al. Identification of a Novel Single Nucleotide Polymorphism in Porcine Beta-Defensin-1 Gene. Asian-Australas J Anim Sci. 2016 Mar;29(3):315-20.

    [3]. Shokrollah Elahi, et al. The Host Defense Peptide Beta-Defensin 1 Confers Protection Against Bordetella Pertussis in Newborn Piglets. Infect Immun. 2006 Apr;74(4):2338-52.