NLS (PKKKRKV) (TFA)

NLS (PKKKRKV) (TFA);

NLS (PKKKRKV) TFA 是一种源于 SV40 large T antigen 的 NLS ,可作为增强核进入方法应用于基因导入。

NLS (PKKKRKV) (TFA)amp;;

NLS (PKKKRKV) (TFA) Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

NLS (PKKKRKV) (TFA) 的其他形式现货产品:

NLS (PKKKRKV) (hydrochloride)

生物活性

NLS (PKKKRKV) TFA is a nuclear localization signal (NLS) derived from the simian virus 40 large tumor antigen (SV40 large T antigen). NLS (PKKKRKV) TFA can function as a method to enhance nuclear entry in the field of gene transfer research[1][2].

体外研究
(In Vitro)

NLS (PKKKRKV) TFA is the minimum nuclear localization signals (NLS) of SV40 T antigen[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

997.16

Formula

C42H79F3N14O10

Sequence Shortening

PKKKRKV

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Zanta MA, et al. Gene delivery: A single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus. Proc Natl Acad Sci U S A. 1999 Jan 5;96(1):91-6.

    [2]. Cao S, et al. Enhanced effect of nuclear localization signal peptide during ultrasound-targeted microbubble destruction-mediated gene transfection. Mol Med Rep. 2017 Jul;16(1):565-572.

NLS (PKKKRKV)

NLS (PKKKRKV);

NLS (PKKKRKV) 是一种源于 SV40 large T antigen 的 NLS,可作为增强核进入方法应用于基因导入。

NLS (PKKKRKV)amp;;

NLS (PKKKRKV) Chemical Structure

CAS No. : 95088-49-6

规格 价格 是否有货
1 mg ¥1000 询问价格 货期
5 mg ¥2500 询问价格 货期
10 mg ¥4250 询问价格 货期

* Please select Quantity before adding items.

NLS (PKKKRKV) 的其他形式现货产品:

NLS (PKKKRKV) (hydrochloride)

生物活性

NLS (PKKKRKV) is a nuclear localization signal (NLS) derived from the simian virus 40 large tumor antigen (SV40 large T antigen). NLS (PKKKRKV) can function as a method to enhance nuclear entry in the field of gene transfer research[1][2].

分子量

883.14

Formula

C40H78N14O8

CAS 号

95088-49-6

Sequence Shortening

PKKKRKV

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Zanta MA, et al. Gene delivery: A single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus. Proc Natl Acad Sci U S A. 1999 Jan 5;96(1):91-6.

    [2]. Cao S, et al. Enhanced effect of nuclear localization signal peptide during ultrasound-targeted microbubble destruction-mediated gene transfection. Mol Med Rep. 2017 Jul;16(1):565-572.

NLS (PKKKRKV) (hydrochloride)

NLS (PKKKRKV) (hydrochloride); 纯度: 98.01%

NLS (PKKKRKV) hydrochloride 是一种源于 SV40 大 T 抗原的 NLS,可作为增强核进入方法应用于基因导入。

NLS (PKKKRKV) (hydrochloride)amp;;

NLS (PKKKRKV) (hydrochloride) Chemical Structure

规格 价格 是否有货 数量
5 mg ¥900 In-stock
10 mg ¥1500 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

NLS (PKKKRKV) hydrochloride is a nuclear localization signal (NLS) derived from the simian virus 40 large tumor antigen (SV40 large T antigen). NLS (PKKKRKV) can function as a method to enhance nuclear entry in the field of gene transfer research[1][2].

分子量

919.60

Formula

C40H79ClN14O8

Sequence

Pro-Lys-Lys-Lys-Arg-Lys-Val

Sequence Shortening

PKKKRKV

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture and light

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)

溶解性数据
In Vitro:;

H2O : 500 mg/mL (543.71 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.0874 mL 5.4371 mL 10.8743 mL
5 mM 0.2175 mL 1.0874 mL 2.1749 mL
10 mM 0.1087 mL 0.5437 mL 1.0874 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Zanta MA, et al. Gene delivery: A single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus. Proc Natl Acad Sci U S A. 1999 Jan 5;96(1):91-6.

    [2]. Cao S, et al. Enhanced effect of nuclear localization signal peptide during ultrasound-targeted microbubble destruction-mediated gene transfection. Mol Med Rep. 2017 Jul;16(1):565-572.