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Poiytech普立泰科PL-GPC50常温凝胶渗透色谱仪

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Poiytech普立泰科PL-GPC50常温凝胶渗透色谱仪

Poiytech普立泰科PL-GPC50常温凝胶渗透色谱仪

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Poiytech普立泰科PL-GPC50常温凝胶渗透色谱仪

PL-GPC50是用于聚合物表征的新款一体式GPC/SEC系统，适用于室温到50度的高分子分析。该系统的进样阀，检测器与色谱柱处于同温区，最大化减少温度差异对仪器的影响。可选粘度检测器，紫外检测器和光散射检测器，实现常温多检测器联用

PL-GPC50是适用于常温到50℃的高分离度，经济实用型GPC系统。该系统的检测器可选择UV检测器及包括示差折光（PL-RI），粘度（PL-BV400RT）及光散射在内的三束检测器。其他的检测器及系统也可根据需要组合。 Polymer Laboratories最新推出用于聚合物特性分析的新款PL-GPC50整体式GPC/SEC系统。PL-GPC50是适用于室温到50℃的高分离度的经济实用型整体式GPC系统。该系统具有精确的溶剂输送系统，自动进样阀，高性能折光检测器及柱温箱。

 

Poiytech普立泰科PL-GPC220高温凝胶渗透色谱仪

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Poiytech普立泰科PL-GPC220高温凝胶渗透色谱仪

Poiytech普立泰科PL-GPC220高温凝胶渗透色谱仪

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Poiytech普立泰科PL-GPC220高温凝胶渗透色谱仪

PL-GPC220高温凝胶色谱具有目前市场上最高的控温范围，适用于最高温度到220℃的聚合物分析的系统。四级温度保护确保仪器安全，确保色谱柱的安全，整套系统通过了非常严格的CE认证，确保实验室及人员安全。同样可选粘度检测器和光散射检测器，还有高温制样系统SP-260,帮助溶解高温样品。

PL-GPC220系统对任何GPC/SEC的应用，在整个操作范围内提供了无可比拟的分析重现性。
PL-GPC220是一台设计用于几乎所有聚合物、溶剂及温度范围（30℃到220℃）的全自动的极其灵活的系统。

溶剂输送系统可加热到30℃以确保有效的、连续的、重现性的溶剂输送，即使溶剂粘度大或者在室温下可能结晶。

Polymer Laboratories的GPC-220适用于操作温度从室温到220℃的聚合物的分析。直观、综合的软件对系统进行全面灵活的控制，专利的双温区自动进样器，方便样品进样前的预热但又不致于使样品发生热降解，特有溶剂传感器，蒸汽报警器，超温保护器多种安全设施保证使用安全。

高温凝胶色谱的终极解决方案
专业的设计让您的操作更加方便
专业的GPC色谱柱，适用于更多的流动相
一体化的设计，无与伦比的温度一致性
专业的售后服务支持和样品测试能力

 

PL1512-5801-安捷伦Agilent液相色谱柱

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  • 型号 PL1512-5801
  • 品牌 Agilent 安捷伦
  • 【简单介绍】

    安捷伦Agilent液相色谱柱 PL1512-5801
    PLRP-S 系列液相色谱柱，粒径8μm，孔径300Å，内径4.6mm，长度250mm。PLRP-S 系列液相色谱柱,基质为苯乙烯-二乙烯基苯共聚物，主要应用于重组多肽/蛋白质

    安捷伦Agilent液相色谱柱  PL1512-5801

     

    PLRP-S 系列液相色谱柱，粒径8μm，孔径300Å，内径4.6mm，长度250mm。PLRP-S 系列液相色谱柱,基质为苯乙烯-二乙烯基苯共聚物，主要应用于重组多肽/蛋白质

    PLRP-S 色谱柱

    * 耐用的弹性填料提供重现性结果，寿命更长

    * 热稳定和化学稳定性高

    * 遵循USP L21 标准

    * 用于生命科学、化学、临床研究、能源、环境、食品和农业、材料科学和制药行业

    * 宽孔径范围（100A-4000A），适合于分离小分子到大分子复合物和多核苷酸

    PLRP-S 系列色谱柱包括各种孔径和填料尺寸，它们都具有相同的化学特性和基本吸附特性。这些

    填料本质上是疏水的，因此不需要键合相、烷基配体来进行反相分离。因此，能得到无硅醇基、无

    重金属离子的高重现性填料。该色谱柱拥有多种产品系列，适用于纳流/微量分离，包括自下而上

    和自上而下的蛋白质组学、分析型分离以及制备级纯化。此外，Process 色谱柱可以用大量散装填

    料进行装填。

    安捷伦Agilent液相色谱柱  PL1512-5801

    PL1512-5801-安捷伦Agilent液相色谱柱

PL-017

发表于由

PL-017;

PL-017 是一种有效的，选择性 μ 阿片受体 (μ opioid receptor) 激动剂，对 125I-FK 33,824 与 μ 位点结合的 IC50 为 5.5 nM。PL-017 在大鼠中产生持久的可逆性缓解疼痛作用。

PL-017amp;;

PL-017 Chemical Structure

CAS No. : 83397-56-2

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

PL-017 is a potent and selective μ opioid receptor agonist with an IC50 of 5.5 nM for 125I-FK 33,824 binding to μ site. PL-017 produces long-lasting, reversible analgesia in rats[1].

IC50 Target

IC50: 5.5 nM (125I-FK 33,824 binding to μ site)[1]
体外研究
(In Vitro)

PL-017 has an IC50 of 10000 nM for 125I-DADLE binding to δ site[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

PL-017 (0.22, 0.45, 0.9 nmol/rat; i.c.v.) has the time of maximum effect of approximately 15 to 30 mm after injection at lower doses and produces analgesia lasting as long as 4 hours with larger doses in male Sprague-Dawley rats weighing 250 to 375 g[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

535.63

Formula

C29H37N5O5
CAS 号

83397-56-2
Sequence Shortening

YP-{N(Me)Phe}-P-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. K J Chang, et al. Potent morphiceptin analogs: structure activity relationships and morphine-like activities. J Pharmacol Exp Ther. 1983 Nov;227(2):403-8.

PL-017 TFA

发表于由

PL-017 TFA;

PL-017 TFA 是一种有效的，选择性 μ 阿片受体 (μ opioid receptor) 激动剂，对125I-FK 33,824 与 μ 位点结合的 IC50 为 5.5 nM。PL-017 TFA 在大鼠中产生持久的可逆性缓解疼痛作用。

PL-017 TFAamp;;

PL-017 TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

PL-017 TFA is a potent and selective μ opioid receptor agonist with an IC50 of 5.5 nM for 125I-FK 33,824 binding to μ site. PL-017 TFA produces long-lasting, reversible analgesia in rats[1].

IC50 Target

IC50: 5.5 nM (125I-FK 33,824 binding to μ site)[1]
体外研究
(In Vitro)

PL-017 TFA has an IC50 of 10000 nM for 125I-DADLE binding to δ site[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

PL-017 TFA (0.22, 0.45, 0.9 nmol/rat; i.c.v.) has the time of maximum effect of approximately 15 to 30 mm after injection at lower doses and produces analgesia lasting as long as 4 hours with larger doses in male Sprague-Dawley rats weighing 250 to 375 g[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

649.66

Formula

C31H38F3N5O7
Sequence Shortening

YP-{N(Me)Phe}-P-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. K J Chang, et al. Potent morphiceptin analogs: structure activity relationships and morphine-like activities. J Pharmacol Exp Ther. 1983 Nov;227(2):403-8.

荧光染料PL553

发表于由

荧光染料Dye Reagents PL553;

PL553 是一种特异性的，具有高度亲和性的白三烯 A4 水解酶 (Leukotriene A4 hydrolase) 荧光发生底物，最大吸收光和发射光分别为 210 nm 和 410 nm。

PL553

PL553 Chemical Structure

CAS No. : 1456872-74-4

规格 价格 是否有货
5 mg ￥3500 询问价格 货期
10 mg ￥6000 询问价格 货期
25 mg ￥12000 询问价格 货期

* Please select Quantity before adding items.

生物活性

PL553 is a specific and high-affinity fluorigenic substrate of Leukotriene A4 hydrolase, with a λmax of 210 nm and λem of 410 nm.

体外研究
(In Vitro)

PL553 is a specific and high-affinity fluorigenic substrate of Leukotriene A4 hydrolase (LTA4H), with a maximum absorption (λmax) of 210 nm and maximum emission (λem) of 410 nm. PL553 is a better LTA4H substrate than (l)-Ala-β-naphthylamide, and resistant to cleavage by other aminopeptidases, but can be cleaved by FAAH. PL553 (40 μM) is used to evaluate the potencies of known inhibitors toward LTA4H[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

508.49

Formula

C28H23F3N2O4
CAS 号

1456872-74-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Poras H, et al. A sensitive fluorigenic substrate for selective in vitro and in vivo assay of leukotriene A4 hydrolase activity. Anal Biochem. 2013 Oct 15;441(2):152-61.
Kinase Assay
[1]

The ability of PL553 to discriminate LTA4H from APN enzymatic activity is tested using the (l)-Ala-β-naphthylamide and PL553 peptide substrates at 40 μM with either APN from porcine kidney (0.33 mU/mL) or recombinant human LTA4H (0.6 μg/mL). The enzymatic reactions proceeds for 1 h at 37°C in a final volume of 100 μL of 50 mM Tris-HCl (pH 7.4) or 50 mM Tris-HCl (pH 7.4) and 100 mM NaCl for APN or LTA4H, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

  • [1]. Poras H, et al. A sensitive fluorigenic substrate for selective in vitro and in vivo assay of leukotriene A4 hydrolase activity. Anal Biochem. 2013 Oct 15;441(2):152-61.

york约克NS-10PL2-M双轴倾角传感器

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york约克NS-10PL2-M双轴倾角传感器

york约克NS-10PL2-M双轴倾角传感器

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品牌：york约克
生产厂家：york约克

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york约克NS-10PL2-M双轴倾角传感器

● 电气连接：板载式
　　● 类型：双轴倾角传感器
　　● 特点：轻重量，抗振能力强
　　● 供电电源：+12～24VDC
　　● 输出：0.3V～4.7V
　　● 精确度：0.001°（分辨率）
　　● 工作温度范围：0～70℃
　　● 量程：-10°～+10°
　　● 典型应用：水平检测