上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Prosaikogenin H(Synonyms: 前柴胡皂苷H；柴胡次皂苷H)
Prosaikogenin H 是 Saikosaponin 的一种肠道代谢产物，具有弱溶血活性。
Prosaikogenin H Chemical Structure
CAS No. : 99365-22-7
规格
是否有货
5 mg
询价
10 mg
询价
25 mg
询价
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生物活性
Prosaikogenin H is an intestinal metabolite of saikosaponin with a weak hemolytic activity[1].
分子量
618.84
Formula
C36H58O8
CAS 号
99365-22-7
中文名称
前柴胡皂苷H；柴胡次皂苷H
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. M Nose, et al. Effects of saikosaponin metabolites on the hemolysis of red blood cells and their adsorbability on the cell membrane. Chem Pharm Bull (Tokyo). 1989 Dec;37(12):3306-10.
Prosaikogenin G 是从柴胡的根中分离出的，对 Ang II 诱导的大鼠系膜细胞增殖具有明显的抑制作用。Prosaikogenin G 对肾脏有保护作用。Prosaikogenin G 是 Saikosaponin d 在胃肠道中的衍生物。
Prosaikogenin G Chemical Structure
CAS No. : 99365-23-8
规格
价格
是否有货
数量
1 mg
￥1600
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5 mg
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10 mg
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Prosaikogenin G 相关产品
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Natural Product Library Plus
Bioactive Compound Library Plus
Natural Product Library
Glycoside Compound Library
生物活性
Prosaikogenin G, isolated from the roots of Buleurum bicaule Helm (Apiaceae), exhibits significant inhibitory effects on rat mesangial cell proliferation induced by Ang II. Prosaikogenin G has protective action on the kidney[1]. Prosaikogenin G is a derivative of Saikosaponin d in the gastrointestinal tract[2].
体外研究 (In Vitro)
Prosaikogenin G (25, 50 μM) has protective action on the kidney for their down-regulated activity to the rat mesangial cell line (MC) proliferation induced by Ang II (1 μM), and does not exhibit injury to the normal MC[1].
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量
618.84
Formula
C36H58O8
CAS 号
99365-23-8
中文名称
柴胡次皂苷G
运输条件
Room temperature in continental US; may vary elsewhere.
上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Prosaikogenin A(Synonyms: 前柴胡皂苷A；柴胡次皂苷A)
Prosaikogenin A 是一种从 Clinopodium chinense 中分离出的三萜皂苷。Prosaikogenin A 对血小板聚集具有显着的促进作用，EC50 值为 12.2 μM。
Prosaikogenin A Chemical Structure
CAS No. : 99365-21-6
规格
是否有货
5 mg
询价
10 mg
询价
25 mg
询价
* Please select Quantity before adding items.
生物活性
Prosaikogenin A is a triterpene saponin isolated from Clinopodium chinense. Prosaikogenin A has significant promoting effects on platelet aggregation with an EC50 value of 12.2 μM[1].
分子量
618.84
Formula
C36H58O8
CAS 号
99365-21-6
中文名称
前柴胡皂苷A；柴胡次皂苷A
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Biao Zeng, et al. A new triterpenoid saponin from Clinopodium chinense (Benth.) O. Kuntze. Nat Prod Res. 2016;30(9):1001-8.
Prosaikogenin D, isolated from the roots of Buleurum bicaule Helm (Apiaceae), has anti-cancer activity[1][2].
体外研究 (In Vitro)
Prosaikogenin D (20, 40, 60 μg/mL) suppresses the proliferation of A549 cells with an IC50 of 57.2 μg/mL[2].
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量
618.84
Formula
C36H58O8
CAS 号
103629-72-7
中文名称
柴胡次皂苷D
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Nan Xu, et al. A new saikogenin from the roots of Bupleurum bicaule. Chin J Nat Med. 2014 Apr;12(4):305-8.
[2]. Lu Shi, et al. A Potential Anti-cancer Compound Separated from the Chloroform Extract of the Chinese Medicine Formula Shenqi San. Curr Med Sci. 2020 Feb;40(1):138-144.
Prosaikogenin F is a monoglycoside with anticancer and hemolytic properties[1][2].
体外研究 (In Vitro)
Prosaikogenin F inhibits A549 proliferation with inhibition rates of 40.53%, 92.62% and 93.07% at concentrations of 20, 40 and 60 μg/mL, respectively[1].
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究 (In Vivo)
In mice, intraperitoneal administration of Saikosaponin A and its intestinal metabolite, Prosaikogenin F, show corticosterone secretion-inducing activity at a dose of 0.1 mmol/kg, and maximally increase it at a dose of 0.4 mmol/kg[3].
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量
618.84
Formula
C36H58O8
CAS 号
99365-20-5
中文名称
前柴胡皂苷F
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Lu Shi, et al. A Potential Anti-cancer Compound Separated from the Chloroform Extract of the Chinese Medicine Formula Shenqi San. Curr Med Sci. 2020 Feb;40(1):138-144.
[2]. M Nose, S Amagaya, et al. Effects of saikosaponin metabolites on the hemolysis of red blood cells and their adsorbability on the cell membrane. Chem Pharm Bull (Tokyo). 1989 Dec;37(12):3306-10.
[3]. M Nose, et al. Corticosterone secretion-inducing activity of saikosaponin metabolites formed in the alimentary tract. Chem Pharm Bull (Tokyo). 1989 Oct;37(10):2736-40.
