标签归档：protease

SLIGRL-NH2(Synonyms: Protease-Activated Receptor-2 Activating Peptide)

发表于由

SLIGRL-NH2;(Synonyms: Protease-Activated Receptor-2 Activating Peptide) 纯度: 99.66%

SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) 是一种蛋白酶激活受体-2 (PAR-2) 激动剂。

SLIGRL-NH2amp;;(Synonyms: Protease-Activated Receptor-2 Activating Peptide)

SLIGRL-NH2 Chemical Structure

CAS No. : 171436-38-7

规格 价格 是否有货 数量
10;mM;*;1 mL in DMSO ￥3179 In-stock
1 mg ￥800 In-stock
5 mg ￥2200 In-stock
10 mg ￥3900 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

* Please select Quantity before adding items.

SLIGRL-NH2 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • GPCR/G Protein Compound Library
  • Immunology/Inflammation Compound Library
  • Peptide Library

生物活性

SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is an agonist of Protease-Activated Receptor-2 (PAR-2)[1].

IC50 Target

PAR-2[1]
体外研究
(In Vitro)

SLIGRL-NH2 is an agonist of PAR-2 and MrgprC11[1]. SLIGRL-NH2 causes an L-NAME-inhibited relaxation. Based on SLIGRL-NH2 causing a concentration-dependent relaxation with an EC50 of 10 µM in endothelium-free preparations in the presence of perivascular adipose tissue (PVAT) , 20 µM is used as a suitable ‘test’ concentration of peptide in subsequent experiments designed to evaluate the effects of potential inhibitors of ADRF release/action. In the endothelium-free aorta preparations, SLIGRL-NH2 causes a concentration-dependent relaxation in preparations only in the presence of PVAT [+PVAT, -ENDO (endothelium)][2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

656.82

Formula

C29H56N10O7
CAS 号

171436-38-7
Sequence

Ser-Leu-Ile-Gly-Arg-Leu-NH2
Sequence Shortening

SLIGRL-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -80deg;C 2 years
-20deg;C 1 year
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

H2O : 110 mg/mL (167.47 mM; Need ultrasonic)

DMSO : 100 mg/mL (152.25 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.5225 mL 7.6124 mL 15.2249 mL
5 mM 0.3045 mL 1.5225 mL 3.0450 mL
10 mM 0.1522 mL 0.7612 mL 1.5225 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂：;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.5 mg/mL (3.81 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (3.81 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂：;10% DMSO ;; 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (3.81 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (3.81 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
  • 3.

    请依序添加每种溶剂：;10% DMSO ;; 90% corn oil

    Solubility: ≥ 2.5 mg/mL (3.81 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (3.81 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。
参考文献

  • [1]. Akiyama T, et al. Behavioral model of itch, alloknesis, pain and allodynia in the lower hindlimb and correlativeresponses of lumbar dorsal horn neurons in the mouse. Neuroscience. 2014 Apr 25;266:38-46.

    [2]. Li Y, et al. Perivascular adipose tissue-derived relaxing factors: release by peptide agonists via proteinase-activated receptor-2 (PAR2) and non-PAR2 mechanisms. Br J Pharmacol. 2011 Dec;164(8):1990-2002.

Proteinase K(Synonyms: Protease K)

发表于由

Proteinase K;(Synonyms: Protease K) 纯度: ge;95.0%

Proteinase K (Protease K) 是可用于蛋白消化的一种非特异性丝氨酸蛋白酶。Proteinase K 在有 SDS 或尿素存在的情况下，在很大 pH 值 (4-12)、盐浓度和温度单位内均有活性。

Proteinase Kamp;;(Synonyms: Protease K)

Proteinase K Chemical Structure

CAS No. : 39450-01-6

规格 价格 是否有货 数量
100 mg ￥1200 In-stock
500 mg ￥3500 In-stock
1 g ; 询价 ;
5 g ; 询价 ;

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Proteinase K 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Proteinase K (Protease K) is a nonspecific serine protease that is useful for general digestion of proteins. Proteinase K is active in the presence of SDS or urea and over a wide range of pH (4-12), salt concentrations, and temperatures[1].

CAS 号

39450-01-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -80deg;C 2 years
-20deg;C 1 year
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

H2O : 25 mg/mL (Need ultrasonic)
参考文献

  • [1]. W Ebeling, et al. Proteinase K From Tritirachium Album Limber. Eur J Biochem . 1974 Aug 15;47(1):91-7.

Protease-Activated Receptor-1, PAR-1 Agonist TFA

发表于由

Protease-Activated Receptor-1, PAR-1 Agonist TFA; 纯度: 99.08%

Protease-Activated Receptor-1, PAR-1 Agonist TFA 是一种选择性蛋白酶激活受体1 (PAR-1) 激动肽。Protease-Activated Receptor-1, PAR-1 Agonist TFA 对应于 PAR1 配体，可通过该受体选择性地模拟凝血酶的作用。

Protease-Activated Receptor-1, PAR-1 Agonist TFAamp;;

Protease-Activated Receptor-1, PAR-1 Agonist TFA Chemical Structure

规格 价格 是否有货 数量
10 mg ￥4250 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

* Please select Quantity before adding items.

Protease-Activated Receptor-1, PAR-1 Agonist TFA 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • GPCR/G Protein Compound Library
  • Immunology/Inflammation Compound Library
  • Anti-Cancer Compound Library
  • Peptide Library

生物活性

Protease-Activated Receptor-1, PAR-1 Agonist TFA is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist TFA corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor[1][2].

体外研究
(In Vitro)

Protease-Activated Receptor-1, PAR-1 Agonist induces activation of protein kinase C isoenzymes alpha and epsilon in human HT-29 colon carcinoma cells expressing PAR1 endogeneously. On the cellular level, Protease-Activated Receptor-1, PAR-1 Agonist and thrombin prompted HT-29 cell migration and matrix adhesion by a PKCepsilon-dependent mechanism as concluded because of the inhibition of PAR1-mediated effects by the PKC inhibitor bisindolylmaleimide I and the PKCepsilon translocation inhibitory peptide EAVSLKPT but not by the PKC inhibitor Gö 6976[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

876.92

Formula

C37H59F3N10O11
Sequence

Thr-Phe-Leu-Leu-Arg-Asn
Sequence Shortening

TFLLRN
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro:;

H2O : 6.67 mg/mL (7.61 mM; ultrasonic and warming and heat to 60°C)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.1404 mL 5.7018 mL 11.4035 mL
5 mM 0.2281 mL 1.1404 mL 2.2807 mL
10 mM — — —

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Stefanie Gödecke, et al. Thrombin-induced ATP release from human umbilical vein endothelial cells. Am J Physiol Cell Physiol. 2012 Mar 15;302(6):C915-23.

    [2]. Heider I, et al. PAR1-type thrombin receptor stimulates migration and matrix adhesion of human colon carcinoma cells by a PKCepsilon-dependent mechanism. Oncol Res. 2004;14(10):475-482.

Protease-Activated Receptor-4(Synonyms: 蛋白酶活化的受体-4)

发表于由

Protease-Activated Receptor-4;(Synonyms: 蛋白酶活化的受体-4) 纯度: 98.14%

Protease-Activated Receptor-4 是转化生长因子受体 4 的激动剂。

Protease-Activated Receptor-4amp;;(Synonyms: 蛋白酶活化的受体-4)

Protease-Activated Receptor-4 Chemical Structure

CAS No. : 245443-52-1

规格 价格 是否有货 数量
5 mg ￥880 In-stock
10 mg ￥1550 In-stock
25 mg ￥3400 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

* Please select Quantity before adding items.

Protease-Activated Receptor-4 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Protease-Activated Receptor-4 is the agonist of proteinase-activated receptor-4 (PAR4).

体外研究
(In Vitro)

GYPGKF-NH2 significantly reduces the agonistic potency of AYPGKF-NH2 by 25-fold[1]. GYPGKF-NH2 (500 μM) does not cause contraction or relaxation of the guinea pig IAS strips[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

666.77

Formula

C33H46N8O7
CAS 号

245443-52-1
Sequence

Gly-Tyr-Pro-Gly-Lys-Phe-NH2
Sequence Shortening

GYPGKF-NH2
中文名称

蛋白酶活化的受体-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -80deg;C 2 years
-20deg;C 1 year
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

H2O : 50 mg/mL (74.99 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.4998 mL 7.4988 mL 14.9977 mL
5 mM 0.3000 mL 1.4998 mL 2.9995 mL
10 mM 0.1500 mL 0.7499 mL 1.4998 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Moschonas IC, et al. Molecular requirements involving the human platelet protease-activated receptor-4 mechanism of activation by peptide analogues of its tethered-ligand. Platelets. 2017 Mar 7:1-10. doi: 10.1080/09537104.2017.1282607. [Epub ahead of print]

    [2]. Huang SC, et al. Proteinase-activated receptor-1 (PAR1) and PAR2 mediate relaxation of guinea pig internal anal sphincter. Regul Pept. 2014 Feb 10;189:46-50.

Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA

发表于由

Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA; 纯度: 98.85%

Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA 是一个蛋白酶活化受体 3 (PAR-3) 的激动剂肽。

Protease-Activated Receptor-3 (PAR-3) (1-6), human TFAamp;;

Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA Chemical Structure

规格 价格 是否有货 数量
5 mg ￥1000 In-stock
10 mg ￥1700 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA is a proteinase-activated receptor (PAR-3) agonist peptide[1].

IC50 Target

PAR-3[1]
分子量

760.76

Formula

C31H47F3N10O9
Sequence Shortening

TFRGAP-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
参考文献

  • [1]. inase-activated receptors differentially modulate in vitro invasion of human pancreatic adenocarcinoma PANC-1 cells in correlation with changes in the expression of CDC42 protein. Pancreas. 2014 Jan; 43(1): 10.1097/MPA.0b013e31829f0b81.

蛋白酶抑制剂（protease inhibitor）

发表于由

蛋白酶抑制剂（protease inhibitor）从广义上指与蛋白酶分子活性中心上的一些基团结合，使蛋白酶活力下降，甚至消失，但不使酶蛋白变性的物质。蛋白酶抑制剂能与蛋白酶的活性部位和变构部位结合，抑制酶的催化活性或阻止酶原转化为有活性的酶，在调节蛋白酶活性和蛋白质代谢等方面起着重要的作用。在一系列的生理病理过程中也起着关键性的调控作用，是生物体内免疫系统的重要组成部分。

在试验方面主要是在分离蛋白时，组织或细胞裂解液中充满了来自溶酶体的酶，并且原来无活性的蛋白酶原被充分激活，开始消化其周围的蛋白质，为避免此因素，蛋白酶抑制剂必须被加入在缓冲液内以阻止蛋白酶对细胞组织的消化作用，哺乳类动物组织分离时比细菌或者其他组织分离时更需要应用蛋白酶抑制剂使组织细胞受到完全的保护。

   Applichem是欧洲权威生化试剂生产商，质优价廉，产品有上万种之多，覆盖了免疫学、细胞学、分子生物学、蛋白组学、植物学、制药与诊断试剂研发生产等领域，已经成为多家世界著名品牌试剂的供应商。Applichem公司的生化试剂还是sigma的供应商，有非常广大的客户群，其生化试剂还有着十分明确的级别划分，从生化级，分子级到生物级，药典级应有尽有。应用如此广泛的蛋白酶抑制剂当然也会在Applichem的产品名单上，相比其他品牌，Applichem的蛋白酶抑制剂要种类众多（胰蛋白酶抑制剂，凝乳蛋白酶抑制剂，各类氨基酸酶类抑制剂等），级别划分明确，活性较高，价格也要低廉很多，并且说明书还会提供详细的溶解使用方案。

  Applichem品牌的蛋白酶抑制剂大都程粉状，高纯度，高活性，溶解使用，操作简单便捷。与其它品牌同类产品相比价格低廉，常备现货。上海金畔生物科技有限公司推荐在常规分离蛋白实验中都可用此类产品。

   Applichem常备蛋白酶抑制剂包括以下几种产品：

产品名称

货号

产品说明（点击查看说明书）

Aprotinin BioChemica

A2132,0010

10mg胰蛋白酶抑制剂

Leupeptin hemisulfate

A2183,0010

10mg亮抑酶肽

APMSF hydrochloride

A0998,0010

10mg血浆丝氨酸蛋白酶抑制剂

AEBSF hydrochloride BioChemica

A1421,0001

1g盐酸盐蛋白类抑制剂

    胰蛋白酶抑制剂，又叫牛胰脏蛋白酶抑制剂（BPTI）或胰酶-激肽释放酶抑制剂（TKI）.是一种很常用到的抑制剂。亮抑酶肽是一种缩氨酸抗生素，是丝氨酸和半胱氨酸累蛋白酶的可逆抑制剂（例如血浆酶，胰蛋白酶，木瓜蛋白酶和组织蛋白酶等）。血浆丝氨酸蛋白酶抑制剂-专门针对血浆丝氨酸类蛋白酶类的不可逆抑制剂。盐酸盐蛋白类抑制剂，可以通过使活性集团中心内的功能区磺酰化来达到不可逆的抑制凝血酶或其他丝氨酸类蛋白酶活性的做用（其中包括糜蛋白酶类，血管舒缓素类，胰蛋白酶类等）。

Applichem除以上几种常用蛋白酶抑制剂外还有其它植物来源的，不同级别的蛋白酶抑制剂可供客户选择，比其他品牌的来源，种类都更加丰富。

AppliChem的所有产品都通过了全球ISO9001资格认证，这保证了所有AppliChem的产品都被精心的监控，并能保证为我们的客户提供他们所需的最优品质的产品. 作为Applichem中国一级代理商，上海金畔生物科技有限公司将一如既往的为您提供最优质的生化试剂和高品质的产品技术服务。除了多种单独的蛋白酶抑制剂以及专门不同的蛋白酶抑制剂混合物产品，上海金畔生物科技有限公司还有多种蛋白提取、蛋白电泳、免疫学一抗、二抗产品以及显色发光底物等实际。我们能为您提供一站式的产品及实验解决方案。如果您对我们的产品感兴趣，请致电021-50837765到上海金畔生物科技有限公司垂询蛋白提取纯化相关的实验解决方案，或者问询您所感兴趣的产品类型。

图片参考：

蛋白酶抑制剂（protease inhibitor）蛋白酶抑制剂（protease inhibitor）蛋白酶抑制剂（protease inhibitor）蛋白酶抑制剂（protease inhibitor）

HIV Protease Substrate 1

发表于由

HIV Protease Substrate 1;

HIV Protease Substrate 1 是一种外源性 HIV 蛋白酶底物，可用于研究 HIV 蛋白酶的酶活性。

HIV Protease Substrate 1amp;;

HIV Protease Substrate 1 Chemical Structure

CAS No. : 223769-59-3

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

HIV Protease Substrate 1, a fiuorogenic HIV protease substrate, can be used to study enzymatic activity of HIV protease[1].

体外研究
(In Vitro)

HIV Protease Substrate 1 is a synthetic peptide sequence that contains the cleavage site (Tyr-Pro) for HIV protease as well as two covalently modified amino acids for the detection of cleavage[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

2017.27

Formula

C92H133N27O23S
CAS 号

223769-59-3
Sequence

Arg-{Glu(EDANS)}-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys{(DABCYL)}-Arg
Sequence Shortening

R{Glu(EDANS)}SQNYPIVQ{Lys(DABCYL)}R
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Kapewangolo P, et al. Anti-HIV Activity of Ocimum labiatum Extract and Isolated Pheophytin-a. Molecules. 2017;22(11):1763. Published 2017 Nov 6.

Protease-Activated Receptor-1, PAR-1 Agonist

发表于由

Protease-Activated Receptor-1, PAR-1 Agonist;

Protease-Activated Receptor-1, PAR-1 Agonist 是一种选择性蛋白酶激活受体1 (PAR-1) 激动肽。Protease-Activated Receptor-1, PAR-1 Agonist 对应于PAR1配体，可通过该受体选择性地模拟凝血酶的作用。

Protease-Activated Receptor-1, PAR-1 Agonistamp;;

Protease-Activated Receptor-1, PAR-1 Agonist Chemical Structure

CAS No. : 141136-85-8

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Protease-Activated Receptor-1, PAR-1 Agonist 的其他形式现货产品:

Protease-Activated Receptor-1, PAR-1 Agonist TFA

生物活性

Protease-Activated Receptor-1, PAR-1 Agonist is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor[1][2].

IC50 Target

PAR-1[1]
体外研究
(In Vitro)

Protease-Activated Receptor-1, PAR-1 Agonist induces activation of protein kinase C isoenzymes alpha and epsilon in human HT-29 colon carcinoma cells expressing PAR1 endogeneously. On the cellular level, Protease-Activated Receptor-1, PAR-1 Agonist and thrombin prompted HT-29 cell migration and matrix adhesion by a PKCepsilon-dependent mechanism as concluded because of the inhibition of PAR1-mediated effects by the PKC inhibitor bisindolylmaleimide I and the PKCepsilon translocation inhibitory peptide EAVSLKPT but not by the PKC inhibitor Gö 6976[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

762.90

Formula

C35H58N10O9
CAS 号

141136-85-8
Sequence

Thr-Phe-Leu-Leu-Arg-Asn
Sequence Shortening

TFLLRN
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Stefanie Gödecke, et al. Thrombin-induced ATP release from human umbilical vein endothelial cells. Am J Physiol Cell Physiol. 2012 Mar 15;302(6):C915-23.

    [2]. Heider I, et al. PAR1-type thrombin receptor stimulates migration and matrix adhesion of human colon carcinoma cells by a PKCepsilon-dependent mechanism. Oncol Res. 2004;14(10):475-482.

Hepatitis Virus C NS3 Protease Inhibitor 2

发表于由

Hepatitis Virus C NS3 Protease Inhibitor 2;

Hepatitis Virus C NS3 Protease Inhibitor 2 是基于产物的丙型肝炎病毒蛋白酶 ( HCV NS3 protease) 肽抑制剂，其 Ki 值为 41 nM。

Hepatitis Virus C NS3 Protease Inhibitor 2amp;;

Hepatitis Virus C NS3 Protease Inhibitor 2 Chemical Structure

CAS No. : 208939-95-1

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生物活性

Hepatitis Virus C NS3 Protease Inhibitor 2 is a product-based peptide inhibitor of hepatitis C virus (HCV) NS3 protease, with a Ki of 41 nM[1].

IC50 Target

HCV NS3 Protease[1]
分子量

913.10

Formula

C43H56N6O14S
CAS 号

208939-95-1
Sequence

Ac-Asp-Glu-{Dif}-Glu-{Cha}-Cys
Sequence Shortening

Ac-DE-{Dif}-E-{Cha}-C
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. A Johansson, et al. Inhibition of hepatitis C virus NS3 protease activity by product-based peptides is dependent on helicase domain. Bioorg Med Chem Lett. 2001 Jan 22;11(2):203-6.

HIV Protease Substrate 1 TFA

发表于由

HIV Protease Substrate 1 TFA;

HIV Protease Substrate 1 TFA 是一种外源性 HIV 蛋白酶底物，可用于研究 HIV 蛋白酶的酶活性。

HIV Protease Substrate 1 TFAamp;;

HIV Protease Substrate 1 TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
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生物活性

HIV Protease Substrate 1 TFA, a fiuorogenic HIV protease substrate, can be used to study enzymatic activity of HIV protease[1].

分子量

2131.29

Formula

C94H134F3N27O25S
Sequence

Arg-{Glu(EDANS)}-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys{(DABCYL)}-Arg
Sequence Shortening

R{Glu(EDANS)}SQNYPIVQ{Lys(DABCYL)}R
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Kapewangolo P, et al. Anti-HIV Activity of Ocimum labiatum Extract and Isolated Pheophytin-a. Molecules. 2017;22(11):1763. Published 2017 Nov 6.