p3Ysh-3

p3Ysh-3;

p3Ysh-3 是 STEP Phosphatase-GluA2 AMPA 受体相互作用的肽抑制剂,Ki 为 1.09 μM。p3Ysh-3 在东莨菪碱处理的大鼠模型中恢复记忆缺陷并表现出抗焦虑和抗抑郁作用。p3Ysh-3 是一种很有前途的先导化合物,可用于新型认知增强剂和/或行为调节剂。

p3Ysh-3amp;;

p3Ysh-3 Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

p3Ysh-3 is a peptide inhibitor of STEP Phosphatase-GluA2 AMPA receptor interaction with a Ki of 1.09 μM. p3Ysh-3 restores the memory deficits and displays anxiolytic and antidepressant effects in a scopolamine-treated rat model. p3Ysh-3 is a promising lead compound for novel cognitive enhancers and/or behavioral modulators[1].

分子量

997.94

Formula

C41H60N9O18P

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Szedlacsek HS, et al. Designed Peptide Inhibitors of STEP Phosphatase-GluA2 AMPA Receptor Interaction Enhance the Cognitive Performance in Rats. J Med Chem. 2022;65(1):217-233.