Rebaudioside A is a steviol glycoside, α-glucosidase inhibitor with IC50 of 35.01 μg/ml.can inhibit ATP-sensitive K+-channels. Target: α-glucosidase [1] IC 50: 35.01 ug/mL In vitro: rebaudioside A stimulat the insulin secretion from MIN6 cells in a dose- and glucose-dependent manner. In conclusion, the insulinotropic effect of rebaudioside A is mediated via inhibition of ATP-sensitive K+-channels and requires the presence of high glucose. [2] In vivo: in vivo mouse micronucleus test at doses up to 750 mg/kg bw and an unscheduled DNA synthesis test in rats at doses up to 2000 mg/kg bw, rebaudioside A do not cause any genotoxic effects at any of the doses tested.[3]
IC50 & Target
Human Endogenous Metabolite
Clinical Trial
分子量
967.01
Formula
C44H70O23
CAS 号
58543-16-1
中文名称
莱苞迪甙 A;瑞鲍迪甙 A;甜菊双糖苷 A;A 甙甜菊糖;甜菊双糖甙 A
运输条件
Room temperature in continental US; may vary elsewhere.
[1]. Adari BR et al. Synthesis of rebaudioside-A by enzymatic transglycosylation of stevioside present in the leaves of Stevia rebaudiana Bertoni. Food Chem. 2016 Jun 1;200:154-8.
[2]. Abudula R et al. Rebaudioside A directly stimulates insulin secretion from pancreatic beta cells: a glucose-dependent action via inhibition of ATP-sensitive K-channels. Diabetes Obes Metab. 2008 Nov;10(11):1074-85.
[3]. Williams LD et al. Genotoxicity studies on a high-purity rebaudioside A preparation. Food Chem Toxicol. 2009 Aug;47(8):1831-6.
Rebaudioside B 是从甜叶菊叶中分离出的次要成分。Rebaudioside B 的甜味是蔗糖的 150 倍。
Rebaudioside B Chemical Structure
CAS No. : 58543-17-2
规格
价格
是否有货
数量
5 mg
¥1190
In-stock
10 mg
¥2020
In-stock
20 mg
¥3430
In-stock
50 mg
;
询价
;
100 mg
;
询价
;
* Please select Quantity before adding items.
Rebaudioside B 相关产品
bull;相关化合物库:
Natural Product Library Plus
Bioactive Compound Library Plus
Natural Product Library
Glycoside Compound Library
Medicine Food Homology Compound Library
生物活性
Rebaudioside B is the minor constituent isolated from the leaves of Stevia rebaudiana Bertoni. Rebaudioside B tastes about 150 times sweeter than sucrose [1].
分子量
804.87
Formula
C38H60O18
CAS 号
58543-17-2
中文名称
甜菊糖B苷
运输条件
Room temperature in continental US; may vary elsewhere.
[1]. Prakash I, et al. Catalytic hydrogenation of the sweet principles of Stevia rebaudiana, Rebaudioside B, Rebaudioside C, and Rebaudioside D and sensory evaluation of their reduced derivatives. Int J Mol Sci. 2012 Nov 16;13(11):15126-36.