Secologanin

天然产物 糖类和糖苷 Saccharides and Glycosides

Secologanin; 纯度: ge;94.0%

Secologanin 是一种裂环烯醚萜苷类化合物,是生物活性单萜类吲哚类生物碱 (如利血平 (HY-N0480)、Ajmaline 和长春碱) 生物合成的关键萜类中间体。Secologanin 合成酶 (细胞色素 P450 亚型 CYP72A1) 催化 loganin 氧化裂解为 Secologanin。

Secologanin

Secologanin Chemical Structure

CAS No. : 19351-63-4

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Secologanin 相关产品

bull;相关化合物库:

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生物活性

Secologanin, a secoiridoid glucoside, is a pivotal terpenoid intermediate in the biosynthesis of biologically active monoterpenoid indole alkaloids such as reserpine, ajmaline, and vinblastine. Secologanin synthase (cytochrome P450 isoform CYP72A1) catalyzes the oxidative cleavage of loganin into Secologanin[1][2].

分子量

388.37

Formula

C17H24O10

CAS 号

19351-63-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20deg;C 3 years
In solvent -80deg;C 6 months
-20deg;C 1 month
参考文献
  • [1]. Inoue K. Yakugaku Zasshi. 2005;125(1):31-49. doi:10.1248/yakushi.125.31

    [2]. Irmler S, et al. Indole alkaloid biosynthesis in Catharanthus roseus: new enzyme activities and identification of cytochrome P450 CYP72A1 as secologanin synthase. Plant J. 2000;24(6):797-804.