Ribostamycin sulfate(Synonyms: 硫酸核糖霉素; Vistamycin sulfate)

天然产物 糖类和糖苷 Saccharides and Glycosides

Ribostamycin sulfate;(Synonyms: 硫酸核糖霉素; Vistamycin sulfate) 纯度: ge;98.0%

Ribostamycin sulfate (Vistamycin sulfate) 是一种广谱抗菌剂, 在30S和50S核糖体亚基结合水平抑制细菌蛋白质合成, 还抑制蛋白二硫键异构酶 (PDI) 分子伴侣活性, 用于药代动力学和肾毒性研究。

Ribostamycin sulfate(Synonyms: 硫酸核糖霉素; Vistamycin sulfate)

Ribostamycin sulfate Chemical Structure

CAS No. : 53797-35-6

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Free Sample (0.1-0.5 mg) ; Apply now ;
10;mM;*;1 mL in Water ¥825 In-stock
50 mg ¥750 In-stock
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生物活性

Ribostamycin sulfate (Vistamycin sulfate) is a broad-spectrum antimicrobial, inhibits bacterial protein synthesis at the level of 30S and 50S ribosomal subunit binding, also inhibits the chaperone activity of protein disulfide isomerase (PDI), used in pharmacokinetic and nephrotoxicity studies

体外研究
(In Vitro)

Ribostamycin is as an intermediate in the biosynthesis of neomycin[1].
Ribostamycin inhibited the chaperone activity of protein disulfide isomerase (PDI), but it did not inhibit the isomerase activity[3].
Ribostamycin is effective against both gram-positive and gram-negative cocci and bacilli including drug-resistant strains. Ribostamycin is especially effective against the gentamicin-resistant bacterium Klebsiella pneumoniae, which possesses aminoglycoside-modifying enzymes[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

552.55

Formula

C17H36N4O14S

CAS 号

53797-35-6

中文名称

硫酸核糖霉素;核糖霉素硫酸盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, sealed storage, away from moisture and light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)

溶解性数据
In Vitro:;

H2O : 130 mg/mL (235.27 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.8098 mL 9.0490 mL 18.0979 mL
5 mM 0.3620 mL 1.8098 mL 3.6196 mL
10 mM 0.1810 mL 0.9049 mL 1.8098 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Baud H, et al. Ribostamycin, as an intermediate in the biosynthesis of neomycin. J Antibiot (Tokyo). 1977 Sep;30(9):720-3.

    [2]. Hunfeld KP, et al. In vitro activity of mezlocillin, meropenem, aztreonam, vancomycin, teicoplanin, ribostamycin and fusidic acid against Borrelia burgdorferi. Int J Antimicrob Agents. 2001 Mar;17(3):203-8.

    [3]. Horibe T, et al. Ribostamycin inhibits the chaperone activity of protein disulfide isomerase. Biochem Biophys Res Commun. 2001 Dec 21;289(5):967-72.

Paromomycin sulfate(Synonyms: 硫酸巴龙霉素; Aminosidine sulfate)

天然产物 糖类和糖苷 Saccharides and Glycosides

Paromomycin sulfate;(Synonyms: 硫酸巴龙霉素; Aminosidine sulfate) 纯度: ge;98.0%

Paromomycin (Aminosidine) sulfate 是一种的广谱氨基糖苷类抗生素 (antibiotic),具有杀螨杀菌作用,是新霉素 (HY-B0470) 衍生物。Paromomycin sulfate 通过与细菌 30S 核糖体 A 位点的 RNA 寡核苷酸特异性结合,使 mRNA 的翻译提前终止,并抑制蛋白质合成。Paromomycin sulfate 可用于细菌和寄生虫感染的研究。

Paromomycin sulfate(Synonyms: 硫酸巴龙霉素; Aminosidine sulfate)

Paromomycin sulfate Chemical Structure

CAS No. : 1263-89-4

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Free Sample (0.1-0.5 mg) ; Apply now ;
10;mM;*;1 mL in Water ¥500 In-stock
500 mg ¥400 In-stock
1 g ¥500 In-stock
5 g ; 询价 ;
10 g ; 询价 ;

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生物活性

Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections[1][2][3].

体外研究
(In Vitro)

Paromomycin sulfate (500 μg/ml) reduces intracellular parasitic forms by 97.2% compared to control in Caco-2 cells and reduces the percentage of intracellular C. parvum forms by 99.5% in HCT-8 cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Paromomycin sulfate (oral gavage; 50 mg/kg-200 mg/kg; once daily; for five consecutive days two weeks post infection) reduces the number of oocyst per gram of feces and intestine. It shows minimal focal inflammation in only 20% of the sections at 50 mg/kg from the intestines of mice infected with C. parvum and only 10% of focal inflammation at 200 mg/kg[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Swiss albino mice[1]
Dosage: 50 mg/kg-200 mg/kg
Administration: Oral gavage; 50 mg/kg-200 mg/kg; once daily; for five consecutive days two weeks post infection
Result: Was against cryptosporidiosis in vivo.

Clinical Trial

分子量

713.71

Formula

C23H47N5O18S

CAS 号

1263-89-4

中文名称

硫酸巴龙霉素

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, sealed storage, away from moisture

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro:;

H2O : 100 mg/mL (140.11 mM; ultrasonic and warming and heat to 80°C)

Ethanol : 1 mg/mL (1.40 mM; Need ultrasonic)

DMSO : 1 mg/mL (1.40 mM; ultrasonic and warming and heat to 80°C)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.4011 mL 7.0056 mL 14.0113 mL
5 mM 0.2802 mL 1.4011 mL 2.8023 mL
10 mM 0.1401 mL 0.7006 mL 1.4011 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Tony J Tavares, et al. Structure of the cytosine-cytosine mismatch in the thymidylate synthase mRNA binding site and analysis of its interaction with the aminoglycoside paromomycin. RNA. 2009 May;15(5):911-22.

    [2]. Mohamed Mammeri, et al. Efficacy of chitosan, a natural polysaccharide, against Cryptosporidium parvum in vitro and in vivo in neonatal mice. Exp Parasitol. 2018 Nov;194:1-8.

    [3]. Ibrahim Aly, et al. Efficacy of Low and High Dose of Paromomycin Sulfate for Treatment of Cryptosporidiosis in Immunosuppressed Infected-Mice.Global Veterinaria 15 (2): 137-143, 2015

Nile Blue A sulfate(Synonyms: Nile blue sulfate)

Nile Blue A sulfate;(Synonyms: Nile blue sulfate) 纯度: ge;98.0%

Nile Blue A (Nile blue sulfate) 可用于区分黑色素和脂褐素。它也可用于脂肪染色,以及制备电流葡萄糖传感器。

Nile Blue A sulfateamp;;(Synonyms: Nile blue sulfate)

Nile Blue A sulfate Chemical Structure

CAS No. : 3625-57-8

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg) ; Apply now ;
10;mM;*;1 mL in DMSO ¥550 In-stock
100 mg ¥500 In-stock
200 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

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生物活性

Nile Blue A (Nile blue sulfate) is used to differentiate melanins and lipofuscins. It is also useful for staining fats and preparation of an amperometric glucose sensor[1].

体外研究
(In Vitro)

Nile blue A is a basic oxazine dye which is soluble in water and ethyl alcohol. Nile blue A is a satisfactory stain for PHB granules in bacteria and is in fact superior to Sudan black B for this purpose. Poly-p3-hydroxybutyrate granules exhibits a strong orange fluorescence when stained with Nile blue A. Nile blue A appears to stain many more PHB granules than Sudan black B does and is not as easily ished from the cell by decolorization procedures[1]. Nile blue A is used as a stain for polyhydroxyalkanoic acid-accumulating microorganisms or to detect polyhydroxyalkanoic acids in microorganisms. Escherichia coli cells that do not accumulate detectable polyhydroxyalkanoic acids can be stained with Nile blue A and that this staining is sufficient for identifying these cells in fluorescence-activated cell sorting (FACS) experiments. Nile blue A staining does not affect either surface display of peptides or specific labeling of these peptides by a second fluorescence. Staining E. coli for flow cytometry using Nile blue A is an easy-to-handle and low-cost alternative to other fluorescent dyes or the intracellular expression of, for example, green fluorescent protein[2]. Nile blue A is one of the most studied benzophenoxazine dyes, as a potent photosensitizer for photodynamic therapy. The dye when administered intravenously disperses throughout the body by circulating through blood and is taken up by most cells that emphasize its interaction with various biomolecule[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

366.42

Formula

C20H20N3O5S

CAS 号

3625-57-8

中文名称

硫酸耐尔蓝A;硫酸尼罗蓝

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, sealed storage, away from moisture and light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)

溶解性数据
In Vitro:;

DMSO : ≥ 150 mg/mL (409.37 mM)

H2O : < 0.1 mg/mL (ultrasonic;warming) (insoluble)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.7291 mL 13.6455 mL 27.2911 mL
5 mM 0.5458 mL 2.7291 mL 5.4582 mL
10 mM 0.2729 mL 1.3646 mL 2.7291 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Ostle AG, et al. Nile blue A as a fluorescent stain for poly-beta-hydroxybutyrate. Appl Environ Microbiol. 1982 Jul;44(1):238-41.

    [2]. Betscheider D, et al. Nile blue A for staining Escherichia coli in flow cytometer experiments. Anal Biochem. 2009 Jan 1;384(1):194-6.

    [3]. Mishra SS, et al. Spectroscopic investigation of interaction of Nile Blue A, a potent photosensitizer, with bile salts in aqueous medium. J Photochem Photobiol B. 2014 Dec;141:67-75.

Cell Assay
[1][2][3]

1% aqueous solution of Nile blue A is prepared and filtered before use. Mild heating may be necessary to fully dissolve the stain. Heat-fixed smears of bacterial cells are stained with the Nile blue A solution at 55°C for 10 min in a coplin staining jar. After being stained, the slides are washed with tap water to remove excess stain and with 8% aqueous acetic acid for 1 min. The stained smear is washed and blotted dry with bibulous paper, remoistened with tap water, and covered with a no. 1 glass cover slip. The preparation is examined with a Nikon Labphot microscope with an episcopic fluorescence attachment[1]. The PHA− strain Escherichia coli UT5600(DE3) is stained with Nile blue A. In an Erlenmeyer flask, 20 mL of Luria–Bertani (LB) broth is inoculated with one colony of UT5600(DE3) and incubated for 14 h at 37 °C and 200 rpm. Subsequently, 20 mL of LB broth containing Nile blue A in a final concentration of 0.5 μg/mL is inoculated with 200 μL of the 14-h culture and cultured to an optical density at 578 nm (OD578) of 0.6. As a control, 20 mL of LB broth (without Nile blue A) is inoculated with 200 μL of the 14-h culture and is also cultured to an optical density at OD578 of 0.6. Every 20 min, the OD578 is determined for both cultures to verify whether there is any influence of the dye on the growth of the bacteria[2]. Nile blue A stock solution is prepared using ethanol as the solvent. The concentration of NB is maintained at 5 μM for all the studies. The solutions are left for 1 h to achieve equilibrium before spectral measurements. The absorption spectra are recorded using Shimadzu Spectrophotometer (UV-1800) and the emission spectra are recorded using Jobin–Yvon Spectrofluorimeter. A 450 nm nano-LED is used as the light source and the fluorescence lifetime is collected at λem=672 nm[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献
  • [1]. Ostle AG, et al. Nile blue A as a fluorescent stain for poly-beta-hydroxybutyrate. Appl Environ Microbiol. 1982 Jul;44(1):238-41.

    [2]. Betscheider D, et al. Nile blue A for staining Escherichia coli in flow cytometer experiments. Anal Biochem. 2009 Jan 1;384(1):194-6.

    [3]. Mishra SS, et al. Spectroscopic investigation of interaction of Nile Blue A, a potent photosensitizer, with bile salts in aqueous medium. J Photochem Photobiol B. 2014 Dec;141:67-75.

Lithium dodecyl sulfate

生化分析试剂 Biochemical Assay Reagents
Lithium dodecyl sulfate;

Lithium dodecyl sulfate 是一种阴离子去污剂和表面活性剂,在低温电泳中可代替 SDS。Lithium dodecyl sulfate 可用于合成纳米材料和色谱分析。

Lithium dodecyl sulfate

Lithium dodecyl sulfate Chemical Structure

CAS No. : 2044-56-6

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Lithium dodecyl sulfate is an anionic detergent and surfactant that can be used in place of SDS for electrophoresis under low temperatures. Lithium dodecyl sulfate can be used for synthesis of nanomaterials and chromatography[1].

分子量

272.33

Formula

C12H25LiO4S

CAS 号

2044-56-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, sealed storage, away from moisture

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)

参考文献
  • [1]. Delepelaire P, et, al. Lithium dodecyl sulfate/polyacrylamide gel electrophoresis of thylakoid membranes at 4 degrees C: Characterizations of two additional chlorophyll a-protein complexes. Proc Natl Acad Sci U S A. 1979 Jan;76(1):111-5.

Paromomycin Sulfate 硫酸巴龙霉素 品牌:FUJIFILM Wako


Paromomycin Sulfate

硫酸巴龙霉素

品牌:FUJIFILM Wako
CAS No.:1263-89-4
储存条件:25℃以下
纯度:
产品编号

(生产商编号)

等级 规格 运输包装 零售价(RMB) 库存情况 参考值

165-23601

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Kanamycin Sulfate

简要描述:CAS号 25389-94-0
分子式 C18H36N4O11·H2SO4
分子量 582.58g/mol
外观 白色或类白色粉末
活性 ≥750ug/mg
溶解性 溶于水(50 mg/mL),几乎不溶于乙醇,氯仿,丙酮
运输 室温运输
保存 室温保存,有效期2年。
级别 USP Grade

产品型号: X10040

所属分类:其他

详情介绍

Kanamycin Sulfate

Kanamycin Sulfate

Kanamycin Sulfate

备货品牌:

Thermo fisher (试剂耗材)、NUNC、Nalgene、QSP、Orion(奥立龙)、优特、Epredia(原Thermo 病理)、Labserv、Corning、Medicom麦迪康、 Xybio试剂、MKbio


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G418 Sulfate (Geneticin) 遗传霉素

简要描述:CAS号 108321-42-2
分子式 C20H40N4O10&#183;2 H2SO4
分子量 692.7g/mol
纯度 ~98%
外观 白色粉末
内毒素含量 <0.5Eu/mg
活力 >700 μg/mg
溶解性 溶于水
运输 常温运输
保存 -20℃避光保存。有效期3年,避免受潮。

产品型号: X10017

所属分类:其他

详情介绍

G418 Sulfate (Geneticin) 遗传霉素

G418 Sulfate (Geneticin) 遗传霉素

G418 Sulfate (Geneticin) 遗传霉素

G418 Sulfate (Geneticin) 遗传霉素

G418 Sulfate (Geneticin) 遗传霉素

G418 Sulfate (Geneticin) 遗传霉素


备货品牌:

Thermo fisher (试剂耗材)、NUNC、Nalgene、QSP、Orion(奥立龙)、优特、Epredia(原Thermo 病理)、Labserv、Corning、Medicom麦迪康、 Xybio试剂、MKbio


优势产品:

Fisherbrand:载玻片 盖玻片 生物危害垃圾袋 肝素化非肝素化毛细管  塑料比色皿  细胞筛网等

原Thermo病理产品Epredia:4951Pluse   p4981 超优 优加刀片3053835 3052835   包埋剂   包埋盒  

Labserv耗材:细胞培养皿 血清移液管 细胞培养瓶 离心管 8联管 EP微量离心管 细胞培养板

Thermo Orion水质分析产品:pH缓冲液 电导标准液 水质分析仪 pH测量仪、电极

Paromomycin Sulfate 硫酸巴龙霉素 品牌:FUJIFILM Wako


Paromomycin Sulfate

硫酸巴龙霉素

品牌:FUJIFILM Wako
CAS No.:1263-89-4
储存条件:25℃以下
纯度:
产品编号

(生产商编号)

等级 规格 运输包装 零售价(RMB) 库存情况 参考值

161-23603

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AppliChem A1492.0025 Gentamycin Sulfate BioChemica 硫酸庆大霉素 1405-41-0 25 g

上海金畔生物科技有限公司提供AppliChem A1492.0025 Gentamycin Sulfate BioChemica 硫酸庆大霉素 1405-41-0 25 g,欢迎访问官网了解更多产品信息和订购

品牌 货号 产品名称 规格 价格

AppliChem A1492.0025 Gentamycin Sulfate BioChemica 硫酸庆大霉素 1405-41-0 25 g 1336.00

AppliChem A1492.0005 Gentamycin Sulfate BioChemica 硫酸庆大霉素 1405-41-0 5 g 523.00

AppliChem A1491.0010 Carbenicillin Disodium Salt BioChemica 羧苄青霉素 4800-94-6 10 g 3656.00

AppliChem A1491.0005 Carbenicillin Disodium Salt BioChemica 羧苄青霉素 4800-94-6 5 g 2124.00

AppliChem A1440.1000 L-Isoleucine (Ph. Eur., USP) pure, pharma grade 异亮氨酸 73-32-5 1 kg 12071.00

AppliChem A1426.1000 L-Leucine (Ph. Eur., USP) pure, pharma grade 亮氨酸 61-90-5 1 kg 3295.00

AppliChem A1425.1000 L-Cysteine (DAB) pure, pharma grade 半胱氨酸 52-90-4 1 kg 25948.00

AppliChem A1422.5000 D(+)-Glucose anhydrous BioChemica 葡萄糖无水 50-99-7 5 kg 2191.00

AppliChem A1422.1000 D(+)-Glucose anhydrous BioChemica 葡萄糖无水 50-99-7 1 kg 673.00

AppliChem A1421.0500 AEBSF Hydrochloride BioChemica AEBSF盐酸盐 生化级30827-99-7 500 mg 3735.00

AppliChem A1421.0001 AEBSF Hydrochloride BioChemica AEBSF盐酸盐 生化级30827-99-7 1 g 4682.00

AppliChem A1420.9025 . . 25 kg 0.00

AppliChem A1420.1000 . . 1 kg 6540.00

AppliChem A1420.0250 . . 250 g 1930.00

AppliChem A1419.1000 L-Threonine (Ph. Eur., USP) pure, pharma grade 苏氨酸 72-19-5 1 kg 5041.00

AppliChem A1402.0100 Methylene Blue (C.I. 52015) BioChemica 美蓝61-73-4 100 g 1617.00

AppliChem A1396.1000 SSC buffer (20X) for molecular biology SSC 缓冲液 (20X) for molecular biology 1 L 944.00

AppliChem A1395.0500 NADPH Tetrasodium Salt 2646-71-1 500 mg 7325.00

AppliChem A1395.0100 NADPH Tetrasodium Salt 2646-71-1 100 mg 1879.00

AppliChem A1395.0001 NADPH Tetrasodium Salt 2646-71-1 1 g 12546.00

Colistin sulfate (Ph. Eur. Grade) 硫酸粘菌素(欧洲药典级) 品牌:Adipogen


Colistin sulfate (Ph. Eur. Grade)

硫酸粘菌素(欧洲药典级)

品牌:Adipogen
CAS No.:1264-72-8
储存条件:+4°C
纯度:>77% (Mixture, primarly Polymyxin E1 and Polymyxin E2).
产品编号

(生产商编号)

等级 规格 运输包装 零售价(RMB) 库存情况 参考值

AG-CN2-0512-M100

100 mg 500.00


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