Hoechst 34580 tetrahydrochloride(Synonyms: HOE 34580 tetrahydrochloride)

Hoechst 34580 tetrahydrochloride;(Synonyms: HOE 34580 tetrahydrochloride) 纯度: 99.58%

Hoechst 34580 tetrahydrochloride是一种细胞渗透性的荧光染料,用于DNA和核染色。

Hoechst 34580 tetrahydrochlorideamp;;(Synonyms: HOE 34580 tetrahydrochloride)

Hoechst 34580 tetrahydrochloride Chemical Structure

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg) ; Apply now ;
5 mg ¥600 In-stock
10 mg ¥900 In-stock
50 mg ¥2400 In-stock
100 mg ¥3400 In-stock
200 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

Hoechst 34580 tetrahydrochloride 相关产品

bull;相关化合物库:

  • Neuronal Signaling Compound Library
  • CNS-Penetrant Compound Library
  • Anti-Alzheimer’s Disease Compound Library
  • Neurodegenerative Disease-related Compound Library
  • Bioactive Compound Library Plus

生物活性

Hoechst 34580 tetrahydrochloride is a cell-permeable fluorescent dye for staining DNA and nuclei.

IC50 Target

Amyloid-β[1]

体外研究
(In Vitro)

Hoechst 34580 prefers to locate near hydrophobic regions with binding affinity with the inhibition constant IC50 of 0.86±0.05 μM for Hoechst 34580. Hoechst 34580 is a good candidate for treating the Alzheimer’s disease by inhibiting Aβ formation. 50 μM Aβ42 solutions co-incubated with 100, 25, 12.5, 3.125, 0.78, and 0.1, 0.01 μM Hoechst 34580 at 37 °C for 70 h. Hoechst 34580 can inhibit the aggregation of Aβ42 in a dose-dependent manner. And the half-maximal concentration (IC50) is examined. The IC50 is obtained by measuring the concentration of Hoechst 34580 while maintaining the Aβ42 concentration which gave 0.86±0.05 μM for Hoechst 34580[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

597.41

Formula

C27H33Cl4N7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, sealed storage, away from moisture and light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)

溶解性数据
In Vitro:;

H2O : 2.67 mg/mL (4.47 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.6739 mL 8.3695 mL 16.7389 mL
5 mM
10 mM

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Thai NQ, et al. Discovery of DNA dyes Hoechst 34580 and 33342 as good candidates for inhibiting amyloid beta formation: in silico and in vitro study. J Comput Aided Mol Des. 2016 Aug;30(8):639-50.

Chitotetraose tetrahydrochloride(Synonyms: 壳聚糖四聚物;壳四糖四盐酸盐)

天然产物 糖类和糖苷 Saccharides and Glycosides

Chitotetraose tetrahydrochloride;(Synonyms: 壳聚糖四聚物;壳四糖四盐酸盐) 纯度: ge;96.0%

Chitotetraose tetrahydrochloride 是一种丛枝菌根 (AM) 真菌短链几丁质寡聚体。Chitotetraose tetrahydrochloride 激活放线菌植物物种中 AM 真菌依赖性保守共生信号通路 (CSSP)。

Chitotetraose tetrahydrochloride(Synonyms: 壳聚糖四聚物;壳四糖四盐酸盐)

Chitotetraose tetrahydrochloride Chemical Structure

CAS No. : 117399-50-5

规格 价格 是否有货 数量
1 mg ¥800 In-stock
5 mg ¥2500 In-stock
10 mg ; 询价 ;
50 mg ; 询价 ;

* Please select Quantity before adding items.

Chitotetraose tetrahydrochloride 相关产品

bull;相关化合物库:

  • Covalent Screening Library Plus
  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Natural Product Library
  • Covalent Screening Library
  • Microbial Metabolite Library

生物活性

Chitotetraose tetrahydrochloride is an arbuscular mycorrhizal (AM) fungal short-chain chitin oligomer. Chitotetraose tetrahydrochloride activates the AM fungal-dependent conserved symbiosis signaling pathway (CSSP) in actinorhizal plant species[1].

分子量

808.48

Formula

C24H50Cl4N4O17

CAS 号

117399-50-5

中文名称

壳聚糖四聚物;壳四糖四盐酸盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, sealed storage, away from moisture

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro:;

H2O : 50 mg/mL (61.84 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.2369 mL 6.1844 mL 12.3689 mL
5 mM 0.2474 mL 1.2369 mL 2.4738 mL
10 mM 0.1237 mL 0.6184 mL 1.2369 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Mireille Chabaud, et al. Chitotetraose activates the fungal-dependent endosymbiotic signaling pathway in actinorhizal plant species. PLoS One. 2019 Oct 10;14(10):e0223149.

AppliChem A7080.0250 Spermine Tetrahydrochloride BioChemica 四盐酸精胺306-67-2 250 g

上海金畔生物科技有限公司提供AppliChem A7080.0250 Spermine Tetrahydrochloride BioChemica 四盐酸精胺306-67-2 250 g,欢迎访问官网了解更多产品信息和订购

品牌 货号 产品名称 规格 价格

AppliChem A7080.0250 Spermine Tetrahydrochloride BioChemica 四盐酸精胺306-67-2 250 g 0.00

AppliChem A7080.0100 Spermine Tetrahydrochloride BioChemica 四盐酸精胺306-67-2 100 g 0.00

AppliChem A7026.5000 Glycine/Sodium hydroxide -Solution for analysis Glycine/Sodium hydroxide -Solution for analysis 5 L 3701.00

AppliChem A7006.1000 Sodium Chloride 5 mol/l (5 M) for molecular biology 氯化钠溶液5 mol/l (5 M) 7647-14-5 1 L 1332.00

AppliChem A7004.0250 AppliClear-Water AppliClear-Water 250 mL 1357.00

AppliChem A6932.0500 Bradford – Solution for protein determination Bradford法蛋白定量试剂盒 500 mL 1623.00

AppliChem A6916.0250 HEPES buffer pH 7.5 (1 M) sterile HEPES buffer pH 7.5 (1 M) sterile 250 mL 2907.00

AppliChem A6906.0250 HEPES buffer pH 8.0 (1 M) sterile HEPES buffer pH 8.0 (1 M) sterile 250 mL 2850.00

AppliChem A6882.0500 D(+)-Raffinose 5-hydrate BioChemica 棉子糖五水 17629-30-0 500 g 16519.00

AppliChem A6882.0100 D(+)-Raffinose 5-hydrate BioChemica 棉子糖五水 17629-30-0 100 g 4676.00

AppliChem A6798.0050 G418 Disulfate – Solution, sterile 108321-42-2 50 mL 3549.00

AppliChem A6798.0020 G418 Disulfate – Solution, sterile 108321-42-2 20 mL 2671.00

AppliChem A6769.0005 n-Decyl-ß-D-Maltoside for crystallography 82494-09-5 5 g 12916.00

AppliChem A6742.0025 n-Nonyl-beta-D-glucopyranoside BioChemica n-Nonyl-beta-D-glucopyranoside BioChemica 69984-73-2 25 g 0.00

AppliChem A6666.2500KG LB-Medium – Powder according to Lennox LB培养基 2.5 kg 7914.00

AppliChem A6666.1000KG LB-Medium – Powder according to Lennox LB培养基 1 kg 3165.00

AppliChem A6352.0250 Ampicillin Sodium Salt (Ph. Eur.) pure, pharma grade 氨苄青霉素钠盐 69-52-3 250 g 9905.00

AppliChem A6352.0100 Ampicillin Sodium Salt (Ph. Eur.) pure, pharma grade 氨苄青霉素钠盐 69-52-3 100 g 5615.00

AppliChem A6352.0025 Ampicillin Sodium Salt (Ph. Eur.) pure, pharma grade 氨苄青霉素钠盐 69-52-3 25 g 1967.00

AppliChem A6279.0250 Riboflavin (Ph. Eur., USP) pure, pharma grade 核黄素/维生素B2 83-88-5 250 g 3544.00

荧光染料DAB(Synonyms: 3,3′ Diaminobenzidine Tetrahydrochloride)

荧光染料Dye Reagents DAB;(Synonyms: 3,3′ Diaminobenzidine Tetrahydrochloride) 纯度: ge;99.0%

DAB (3,3′ Diaminobenzidine Tetrahydrochloride) 是有机化合物,具有化学和热力学稳定性,可用于核酸和蛋白的免疫组化染色。

DABamp;;(Synonyms: 3,3

DAB Chemical Structure

CAS No. : 7411-49-6

规格 价格 是否有货 数量
500 mg ¥400 In-stock
1 g ¥650 In-stock
5 g ; 询价 ;
10 g ; 询价 ;

* Please select Quantity before adding items.

生物活性

DAB (3,3′ Diaminobenzidine Tetrahydrochloride) is an organic compound that is both chemically and thermodynamically stable; DAB has been used in immunohistochemical staining of nucleic acids and proteins.

分子量

360.11

Formula

C12H18Cl4N4

CAS 号

7411-49-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, protect from light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)

溶解性数据
In Vitro:;

H2O : 60 mg/mL (166.62 mM; Need ultrasonic)

DMSO : ≥ 43 mg/mL (119.41 mM)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.7769 mL 13.8846 mL 27.7693 mL
5 mM 0.5554 mL 2.7769 mL 5.5539 mL
10 mM 0.2777 mL 1.3885 mL 2.7769 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Hannetz Roschzttardtz, et al. Plant Cell Nucleolus as a Hot Spot for Iron.

荧光染料DAB(Synonyms: 3,3′ Diaminobenzidine Tetrahydrochloride)

荧光染料Dye Reagents DAB;(Synonyms: 3,3′ Diaminobenzidine Tetrahydrochloride) 纯度: ge;99.0%

DAB (3,3′ Diaminobenzidine Tetrahydrochloride) 是有机化合物,具有化学和热力学稳定性,可用于核酸和蛋白的免疫组化染色。

DAB(Synonyms: 3,3

DAB Chemical Structure

CAS No. : 7411-49-6

规格 价格 是否有货 数量
500 mg ¥400 In-stock
1 g ¥650 In-stock
5 g ; 询价 ;
10 g ; 询价 ;

* Please select Quantity before adding items.

生物活性

DAB (3,3′ Diaminobenzidine Tetrahydrochloride) is an organic compound that is both chemically and thermodynamically stable; DAB has been used in immunohistochemical staining of nucleic acids and proteins.

分子量

360.11

Formula

C12H18Cl4N4

CAS 号

7411-49-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, protect from light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)

溶解性数据
In Vitro:;

H2O : 60 mg/mL (166.62 mM; Need ultrasonic)

DMSO : ≥ 43 mg/mL (119.41 mM)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.7769 mL 13.8846 mL 27.7693 mL
5 mM 0.5554 mL 2.7769 mL 5.5539 mL
10 mM 0.2777 mL 1.3885 mL 2.7769 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Hannetz Roschzttardtz, et al. Plant Cell Nucleolus as a Hot Spot for Iron.