Transdermal Peptide Disulfide TFA;(Synonyms: TD 1 Disulfide(peptide) TFA) 纯度: 98.45%
Transdermal Peptide Disulfide TFA (TD 1 Disulfide(peptide) TFA) 是由 11 个氨基酸组成的多肽,可以与 Na+/K+-ATPase beta-subunit (ATP1B1) 结合,主要与 ATP1B1 的 C 末端相互作用。Transdermal Peptide Disulfide TFA 能够增强一些大分子在皮肤中的传递。
Transdermal Peptide Disulfide TFA Chemical Structure
规格 | 价格 | 是否有货 | 数量 |
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1 mg | ¥800 | In-stock | |
5 mg | ¥1800 | In-stock | |
10 mg | ¥2800 | In-stock | |
50 mg | ; | 询价 | ; |
100 mg | ; | 询价 | ; |
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Transdermal Peptide Disulfide TFA 相关产品
bull;相关化合物库:
- Bioactive Compound Library Plus
- Macrocyclic Compound Library
- Peptide Library
生物活性 |
Transdermal Peptide Disulfide TFA (TD 1 Disulfide(peptide) TFA) is a 11-amino acid peptide, binds to Na+/K+-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide Disulfide TFA can enhance the transdermal delivery of many macromolecules[1]. |
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体外研究 (In Vitro) |
In the presence of Transdermal Peptide Disulfide, because of the specific binding of Transdermal Peptide Disulfide to ATP1B1, cells will upregulate the level of ATP1B1 to maintain function and structure; as a result, the expression of ATP1B1 increases. However, as time goes on, some Transdermal Peptide Disulfide molecules may be transported into cells by endocytosis; consequently, the expression of ATP1B1 then decreases. The interaction between Transdermal Peptide Disulfide and ATP1B1 changes not only the expression of ATP1B1, but also the localization of ATP1B1 and then the structure of the epidermal layer. This interaction can be attenuated by inhibitors or competitors, which would result in the reduced delivery of macromolecular drugs across the skin[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
1175.17 |
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Formula |
C42H65F3N14O18S2 |
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Sequence Shortening |
ACSSSPSKHCG (Disulfide bridge: Cys2-Cys10) |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Sealed storage, away from moisture
*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture) |
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溶解性数据 |
In Vitro:;
H2O : 100 mg/mL (85.09 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
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参考文献 |
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