天然产物 天然产物苯丙素类 Phenylpropanoids
Osthenol (Synonyms: Ostenol) 纯度: 98.91%
Osthenol (Ostenol) 是从独活干根中分离得到的一种前酰化香豆素,是一种可逆的,选择性的竞争性人单胺氧化酶-A (hMAO-A) 抑制剂 (Ki=0.26 µM)。Osthenol 对重组 hMAO-A 具有潜在的选择性抑制作用,IC50为 0.74 µM,对hMAO-A和hMAO-B表现出较高的选择性指数。
Osthenol Chemical Structure
CAS No. : 484-14-0
规格 | 价格 | 是否有货 | 数量 |
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1 mg | ¥1200 | In-stock | |
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Osthenol 相关产品
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生物活性 |
Osthenol (Ostenol), a prenylated coumarin isolated from the dried roots of Angelica pubescens, is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 µM and shows a high selectivity index for hMAO-A versus hMAO-B[1]. |
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IC50 & Target[1] |
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分子量 |
230.26 |
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Formula |
C14H14O3 |
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CAS 号 |
484-14-0 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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参考文献 |
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