GE 离子交换填料17071905 17-0719-05


GE 离子交换填料17071905

GE 离子交换填料17071905 CM Sepharose,Fast Flow包装:10升/桶. GE 离子交换填料17071905为弱阳离子交换填料。另外有25ml,500ml三种不同包装可选择。

  CM Sepharose,Fast Flow GE 离子交换填料17071905每毫升载有50mg核糖核酸酶,颗粒大小为90um,应用于经济的精细纯化。

 PH稳定性工作4-13,清洗2-14,

 耐压 0.3MPa

 限制流速 750 CM/H

  CM Sepharose,Fast Flow  GE 离子交换填料17071905具有高化学稳定性,能承受各种效正样品。配合有效的在位清洗,可反复重生过千次。  还具有高流速加上高载量的特点,能快速纯化大量粗产品。

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货号               产品                   包装           每毫升载量         颗粒大小μm      特性/应用                  PH稳定性工作(清洗)  耐压mpa    zui高流速cm/h

17071910     CM Sepharose     25ml               50mg                   90            快速,高产量纯化              4-13                      0.3               750

17071901        F.F                 500ml           核糖核酸酶                                                                  【2-14】

17071905                             10L

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Linoleyl methane sulfonate

生化分析试剂 Biochemical Assay Reagents
Linoleyl methane sulfonate;

Linoleyl methane sulfonate 可作为选择性的脂质载体,用于药物递送系统。

Linoleyl methane sulfonate

Linoleyl methane sulfonate Chemical Structure

CAS No. : 51154-39-3

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
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生物活性

Linoleyl methane sulfonate is a selective lipid-based vehicle for use in drug delivery systems[1].

分子量

344.55

Formula

C19H36O3S

CAS 号

51154-39-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. C Glass, et al. Dissociation of tissue uptake of cholesterol ester from that of apoprotein A-I of rat plasma high density lipoprotein: selective delivery of cholesterol ester to liver, adrenal, and gonad. Proc Natl Acad Sci U S A. 1983 Sep;80(17):5435-9.

1,2-Dihydrotanshinone(Synonyms: 1,2-Dihydrotanshinquinone)

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

1,2-Dihydrotanshinone (Synonyms: 1,2-Dihydrotanshinquinone)

1,2-Dihydrotanshinone (1,2-Dihydrotanshinquinone) 是一种松香烷二萜。1,2-Dihydrotanshinone 抑制 (CUG) n-RNA 和剪接因子 muscleblind-like 1 之间形成的致病复合物的形成。1,2-Dihydrotanshinone 可用于强直性肌营养不良 1 型的研究。

1,2-Dihydrotanshinone(Synonyms: 1,2-Dihydrotanshinquinone)

1,2-Dihydrotanshinone Chemical Structure

CAS No. : 77769-21-2

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

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生物活性

1,2-Dihydrotanshinone (1,2-Dihydrotanshinquinone) is an abietane diterpene. 1,2-Dihydrotanshinone inhibits the formation of the pathogenic complex formed between (CUG)n-RNA and the splicing-factor muscleblind-like 1 (MBNL1). 1,2-Dihydrotanshinone can be used for the research of myotonic dystrophy type 1[1][2].

体外研究
(In Vitro)

1,2-Dihydrotanshinone inhibits the formation of the pathogenic complex formed between (CUG)n-RNA and the splicing-factor muscleblind-like 1 (MBNL1) (≥50% inhibition at 100 µg/mL)[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

278.30

Formula

C18H14O3

CAS 号

77769-21-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Faleschini MT, et, al. Discovery of natural products potentially active against myotonic dystrophy type 1. Planta Med 2015; 81-YRW_03.

    [2]. Fronza M, et, al. In vitro cytotoxic activity of abietane diterpenes from Peltodon longipes as well as Salvia miltiorrhiza and Salvia sahendica. Bioorg Med Chem. 2011 Aug 15;19(16):4876-81.

Luciferase(Synonyms: 荧光素酶)

Luciferase;(Synonyms: 荧光素酶)

Luciferase,来自Vibrio fischeri,可用于评估生物发光细菌的光发射和氧消耗动力学。

Luciferase (Synonyms: 荧光素酶)

Luciferase Chemical Structure

CAS No. : 9014-00-0

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1 mg ¥1100 In-stock
5 mg ¥3000 In-stock
10 mg ¥5000 In-stock
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Luciferase 相关产品

相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Luciferase from Vibrio fischeri has also been used in a study to investigate the sensitivity of dark mutants of various strains of luminescent bacteria to reactive oxygen species.

CAS 号

9014-00-0

中文名称

荧光素酶

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -80°C 2 years
-20°C 1 year
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro:;

H2O : 50 mg/mL (Need ultrasonic)

Poiytech普立泰科PL-GPC50常温凝胶渗透色谱仪

Poiytech普立泰科PL-GPC50常温凝胶渗透色谱仪

Poiytech普立泰科PL-GPC50常温凝胶渗透色谱仪

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Poiytech普立泰科PL-GPC50常温凝胶渗透色谱仪

PL-GPC50是用于聚合物表征的新款一体式GPC/SEC系统,适用于室温到50度的高分子分析。该系统的进样阀,检测器与色谱柱处于同温区,最大化减少温度差异对仪器的影响。可选粘度检测器,紫外检测器和光散射检测器,实现常温多检测器联用

PL-GPC50是适用于常温到50℃的高分离度,经济实用型GPC系统。该系统的检测器可选择UV检测器及包括示差折光(PL-RI),粘度(PL-BV400RT)及光散射在内的三束检测器。其他的检测器及系统也可根据需要组合。 Polymer Laboratories最新推出用于聚合物特性分析的新款PL-GPC50整体式GPC/SEC系统。PL-GPC50是适用于室温到50℃的高分离度的经济实用型整体式GPC系统。该系统具有精确的溶剂输送系统,自动进样阀,高性能折光检测器及柱温箱。

 

Cirsilineol(Synonyms: 甲基条叶蓟素)

天然产物 黄酮类 Flavonoids

Cirsilineol (Synonyms: 甲基条叶蓟素) 纯度: ≥98.0%

Cirsilineol 是一种天然黄酮化合物,可选择性抑制肠道 CD4+ T 细胞中的 IFN-γ/STAT1/T-bet 信号。Cirsilineol 具有免疫抑制和抗肿瘤特性。Cirsilineol 显着改善三硝基苯磺酸 (TNBS) 诱导的小鼠 T 细胞介导的实验性结肠炎。

Cirsilineol(Synonyms: 甲基条叶蓟素)

Cirsilineol Chemical Structure

CAS No. : 41365-32-6

规格 价格 是否有货 数量
1 mg ¥4200 In-stock
5 mg ¥14800 In-stock
10 mg   询价  
50 mg   询价  

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生物活性

Cirsilineol, a natural flavone compound, selectively inhibits IFN-γ/STAT1/T-bet signaling in intestinal CD4+ T cells. Cirsilineol has potent immunosuppressive and anti-tumor properties. Cirsilineol significantly ameliorates trinitro-benzene sulfonic acid (TNBS)-induced T-cell-mediated experimental colitis in mice[1].

体外研究
(In Vitro)

Cirsilineol (0.1-10 μM; 96 hours) inhibits single mixed lymphocyte reaction and Concanava A-induced T-cell proliferation in a dose-dependent manner. Cirsilineol (10 μM) does not affect T lymphocyte’s viability. The inhibition of cirsilineol (10 μM) on T-cell proliferation is not due to a cytotoxic activity[1].
Cirsilineol (1-10 μM; pretreatment for 3 hours) completely inhibits IFN-γ-induced Tyr701 phosphorylation of STAT1 and JAK2 activation[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[1]

Cell Line: Splenocytes
Concentration: 0.1, 1, 10 μM
Incubation Time: 96 hours
Result: Inhibited single mixed lymphocyte reaction and Concanavalin A (Con A; 5 μg/mL; for 72 h)-induced T-cell proliferation in a dose-dependent manner.
Suppressed OVA323-339-specific CD4+ T-cell proliferation.

Western Blot Analysis[1]

Cell Line: Splenic CD4+ T cells
Concentration: 1, 5, 10 μM
Incubation Time: Pretreatment for 3 hours
Result: Completely inhibited IFN-γ-induced (25 ng; 30 mins) Tyr701 phosphorylation of STAT1 and JAK2 activation.
Suppressed IFN-γ-induced (25 ng; 12 hours) Th1-specific transcription factor T-bet.

体内研究
(In Vivo)

cirsilineol (3, 10, and 30 mg/kg) significantly ameliorates TNBS-induced Th1-mediated colitis through inhibiting IFN-γ/STAT1/T-bet signaling in CD4+ T cells.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 8-10-week-old female C57BL/6, BALB/c and DO11.10 transgenic mice with TNBS (10 mg; 100 μL)[1]
Dosage: 3, 10, 30 mg/kg
Administration: IP; daily; for 11 days
Result: Showed a significant improved effect on the body weights and survival rate of mice.
Markedly reduced inflammatory infiltration, restoration of the destructive mucosal architecture and remission of edema.

分子量

344.32

Formula

C18H16O7

CAS 号

41365-32-6

中文名称

甲基条叶蓟素

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

参考文献
  • [1]. Yang Sun, et al. Novel immunomodulatory properties of cirsilineol through selective inhibition of IFN-gamma signaling in a murine model of inflammatory bowel disease. Biochem Pharmacol. 2010 Jan 15;79(2):229-38.

Mogroside IV-A(Synonyms: 罗汉果苷 IV-A;罗汉果甜苷 IV-A;罗汉果甙 IV-A;罗汉果甜甙 IV-A)

天然产物 糖类和糖苷 Saccharides and Glycosides

Mogroside IV-A;(Synonyms: 罗汉果苷 IV-A;罗汉果甜苷 IV-A;罗汉果甙 IV-A;罗汉果甜甙 IV-A) 纯度: 98.83%

Mogroside IV-A 是一种三萜糖苷,可从罗汉果提取物中分离出来。Mogroside IV-A 是一种非糖类甜味剂。Mogroside 比蔗糖更甜。Mogroside 具有抗氧化,抗糖尿病和抗癌活性。

Mogroside IV-A(Synonyms: 罗汉果苷 IV-A;罗汉果甜苷 IV-A;罗汉果甙 IV-A;罗汉果甜甙 IV-A)

Mogroside IV-A Chemical Structure

CAS No. : 88901-41-1

规格 价格 是否有货 数量
5 mg ¥3360 In-stock
10 mg ¥5710 In-stock
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Mogroside IV-A 相关产品

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  • Natural Product Library Plus
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  • Natural Product Library
  • Anti-Cancer Compound Library
  • Diabetes Related Compound Library
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  • Medicine Food Homology Compound Library
  • Terpenoids Library

生物活性

Mogroside IV-A, a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities[1].

分子量

1125.29

Formula

C54H92O24

CAS 号

88901-41-1

中文名称

罗汉果苷 IV-A;罗汉果甜苷 IV-A;罗汉果甙 IV-A;罗汉果甜甙 IV-A

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, protect from light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)

溶解性数据
In Vitro:;

DMSO : 100 mg/mL (88.87 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.8887 mL 4.4433 mL 8.8866 mL
5 mM 0.1777 mL 0.8887 mL 1.7773 mL
10 mM 0.0889 mL 0.4443 mL 0.8887 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂:;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.5 mg/mL (2.22 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (2.22 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂:;10% DMSO ;; 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (2.22 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (2.22 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中,混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中,再用生理盐水定容至 10 mL,完全溶解,澄清透明
  • 3.

    请依序添加每种溶剂:;10% DMSO ;; 90% corn oil

    Solubility: ≥ 2.5 mg/mL (2.22 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (2.22 mM,饱和度未知) 的澄清溶液,此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中,混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。
参考文献
  • [1]. Ukiya M, et al. Inhibitory effects of cucurbitane glycosides and other triterpenoids from the fruit of Momordica grosvenori on epstein-barr virus early antigen induced by tumor promoter 12-O-tetradecanoylphorbol-13-acetate. J Agric Food Chem. 2002 Nov 6;50(23):6710-5.

OHAUS奥豪斯外校型电子天平

OHAUS奥豪斯外校型电子天平

OHAUS奥豪斯外校型电子天平CAV4102C

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OHAUS奥豪斯外校型电子天平CAV4102C独特的应用特点:
1.自动内部校准功能
2.计件称量模式
3.求和称量模式
4.可多种称量单位转换和设定自定义单位
5.称量环境参数设置:自动零点跟踪、多级过滤选择
6.自动去皮
7.自动关机模式
8.内置式下秤钩
9.前置式指示水平泡
10.符合GLP规范的打印设定和数据输出
11.标配RS232通讯接口(可选配第二RS232接口)
12.标配机架塑料保护罩

13.可选配检重报警器

OHAUS奥豪斯外校型电子天平CAV4102C技术参数:
型号
CAV4102C
量程(g
4100
可读性(g
0.01
重复性(标准偏差)(g
0.01
线性误差(±g
±0.02
操作温度范围(
10-30
校准
自动内部校准
秤盘尺寸(cm
16.8×18
电源要求
交流适配器(包括)
外形尺寸(宽××长)(cm
22×8.5×30 

Hoechst 33258 analog

Hoechst 33258 analog; 纯度: 99.96%

Hoechst 33258 analog 是DNA蓝色荧光染料。

Hoechst 33258 analogamp;;

Hoechst 33258 analog Chemical Structure

CAS No. : 258843-62-8

规格 价格 是否有货 数量
10;mM;*;1 mL in DMSO ¥3932 In-stock
5 mg ¥3500 In-stock
10 mg ¥5000 In-stock
50 mg ¥15000 In-stock
100 mg ¥21000 In-stock
200 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

Hoechst 33258 analog 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus

生物活性

Hoechst 33258 analog are part of a family of blue fluorescent dyes used to stain DNA. IC50 Value: Target: These Bis-benzimides were originally developed by Hoechst AG, which numbered all their compounds so that the dye Hoechst 33342 is the 33342nd compound made by the company. There are three related Hoechst stains: Hoechst 33258, Hoechst 33342, and Hoechst 34580. The dyes Hoechst 33258 and Hoechst 33342 are the ones most commonly used and they have similarexcitation/emission spectra. Both dyes are excited by ultraviolet light at around 350 nm, and both emit blue/cyan fluorescent light around anemission maximum at 461 nm. Unbound dye has its maximum fluorescence emission in the 510-540 nm range. Hoechst dyes are soluble in water and in organic solvents such as dimethyl formamide or dimethyl sulfoxide. Concentrations can be achieved of up to 10 mg/mL. Aqueous solutions are stable at 2-6 °C for at least six months when protected from light. For long-term storage the solutions are instead frozen at ≤-20 °C. The dyes bind to the minor groove of double-stranded DNA with a preference for sequences rich in adenine andthymine. Although the dyes can bind to all nucleic acids, AT-rich double-stranded DNA strands enhance fluorescence considerably. Hoechst dyes are cell-permeable and can bind to DNA in live or fixed cells. Therefore, these stains are often called supravital, which means that cells survive a treatment with these compounds. Cells that express specific ATP-binding cassette transporter proteins can also actively transport these stains out of their cytoplasm.

分子量

510.59

Formula

C29H30N6O3

CAS 号

258843-62-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, protect from light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)

溶解性数据
In Vitro:;

DMSO : ≥ 51 mg/mL (99.88 mM)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.9585 mL 9.7926 mL 19.5852 mL
5 mM 0.3917 mL 1.9585 mL 3.9170 mL
10 mM 0.1959 mL 0.9793 mL 1.9585 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. a b c “Hoechst Stains”. Invitrogren (Molecular Probes).

    [2]. Latt SA, Stetten G, Juergens LA, Recent developments in the detection of deoxyribonucleic acid synthesis by 33258 Hoechst fluorescence. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 23 (7): 493-505.

    [3]. Portugal J, Waring MJ. Assignment of DNA binding sites for 4′,6-diamidine-2-phenylindole and bisbenzimide (Hoechst 33258). A comparative footprinting study. Biochimica et Biophysica Acta 949 (2): 158-68.

Caesappanin C

天然产物 天然产物苯丙素类 Phenylpropanoids

Caesappanin C 

Caesappanin C 是一种来自印度尼西亚 Caesalpinia sappan L. 心材的乙醇提取物的联苯二聚体,在体外显示出对原代成骨细胞的强增殖刺激活性。 Caesappanin C 具有刺激骨形成和再生的潜力。

Caesappanin C

Caesappanin C Chemical Structure

CAS No. : 1913319-59-1

规格 价格 是否有货
5 mg ¥2520 询问价格 & 货期
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生物活性

Caesappanin C, a biphenyl dimer from the ethanolic extract of the heartwood of Indonesian Caesalpinia sappan L., shows strong proliferation stimulating activity against the primary osteoblastic cells in vitro. Caesappanin C has the potential to stimulate bone formation and regeneration[1].

分子量

608.59

Formula

C32H32O12

CAS 号

1913319-59-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Subehan, et al. Phytochemical investigation of the active constituents from Caesalpinia sappan on stimulation of osteoblastic cells. Plant Biotechnology, 2014,31(5), 505–509.