Mastoparan(Synonyms: 黄峰毒素)

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Mastoparan;(Synonyms: 黄峰毒素) 纯度: 95.47%

Mastoparan 是一种十四肽，是黄蜂毒液的一种组分，刺激催乳素从大鼠垂体前叶细胞中释放 。

Mastoparanamp;;(Synonyms: 黄峰毒素)

Mastoparan Chemical Structure

CAS No. : 72093-21-1

规格 价格 是否有货 数量
1 mg ￥990 In-stock
5 mg ￥3950 In-stock
10 mg ￥6200 In-stock
25 mg ￥12000 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

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Mastoparan 相关产品

bull;相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Mastoparan, a tetradecapeptide which is a component of wasp venom, stimulates release of prolactin from cultured rat anterior pituitary cells.

体外研究
(In Vitro)

Mastoparan has an amphiphilic nature and is reported to exert a variety of pharmacological and biochemical effects. Mastoparan induces exocytosis of hormones from anterior pituitary cells. Mastoparan stimulation of prolactin secretion is dose-dependent, time-dependent, reversible and required the presence of calcium. Mastoparan causes translocation of protein kinase C activity from a soluble to a membrane-attached form. Mastoparan is able to increase the intracellular Ca2+ concentration in Fura-2-loaded individual lactotrophs. Mastoparan is also able to interact with GTP-bindmg proteins. Thus, Mastoparan has been shown to facilitate exchange of nucleotides and to stimulate GTPase activity on G-proteins. It has therefore been proposed that the cellular effects of Mastoparan are due to an ability to mimic G-protein-linked agonist-liganded receptors[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1478.91

Formula

C70H131N19O15
CAS 号

72093-21-1
Sequence

Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2
Sequence Shortening

INLKALAALAKKIL-NH2
中文名称

黄峰毒素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -80deg;C 2 years
-20deg;C 1 year
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

H2O : 33.33 mg/mL (22.54 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.6762 mL 3.3809 mL 6.7617 mL
5 mM 0.1352 mL 0.6762 mL 1.3523 mL
10 mM 0.0676 mL 0.3381 mL 0.6762 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Mau SE, et al. Mastoparan, a wasp venom peptide, stimulates release of prolactin from cultured rat anterior pituitary cells. J Endocrinol. 1994 Jul;142(1):9-18.