标签归档：acid

L-Diguluronic acid

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天然产物 糖类和糖苷 Saccharides and Glycosides

L-Diguluronic acid;

L-Diguluronic acid 是一种由两个 L-guluronic acid (G) 组成的直链多糖共聚物，可用于海藻酸的合成。L-Diguluronic acid 是一种无支链聚阴离子多糖的总称，可用于抗真菌 (antifungal) 试剂的载体研究。

L-Diguluronic acid

L-Diguluronic acid Chemical Structure

CAS No. : 34044-54-7

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5 mg ￥2500 询问价格 货期

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生物活性

L-Diguluronic acid is a linear polysaccharide copolymer composed of two L-guluronic acid (G) and can be used to from Alginate[1]. Alginate is a generic name of unbranched polyanionic polysaccharides and can be used for the research of antifungal agents delivery carries[2].

体外研究
(In Vitro)

Alginate is a generic name assigned to a series of polyanionic polysaccharides of β-d-mannuronic acid (M) and α-l-guluronic acid (G). Alginate is linked by a 1→4 linkage and displaying chain homosequences of MMM and GGG, interdispersed with MGM heterosequences[1].
Alginate is widely used for obtainment of drug delivery systems due to its non-toxicity, biodegradability, biocompatibility, mucoadhesive, and non-immunogenic properties. Additionally, alginate-based antifungal delivery systems have great potential in the treatment of fungal infections in vivo[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

370.26

Formula

C12H18O13
CAS 号

34044-54-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. R.A. Shirwaiker, et al. L-Guluronic Acid

    [2]. Cristina de Castro Spadari, et al. Potential Use of Alginate-Based Carriers As Antifungal Delivery System.Front Microbiol. 2017 Jan 30;8:97.

D-Tetramannuronic acid(Synonyms: D-甘露糖醛酸四糖)

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天然产物 糖类和糖苷 Saccharides and Glycosides

D-Tetramannuronic acid;(Synonyms: D-甘露糖醛酸四糖)

D-Tetramannuronic acid 是一种藻酸盐低聚物，是由海洋褐藻和某些革兰氏阴性细菌产生的。D-Tetramannuronic acid 可用于疼痛和血管性痴呆的研究。

D-Tetramannuronic acid(Synonyms: D-甘露糖醛酸四糖)

D-Tetramannuronic acid Chemical Structure

CAS No. : 149511-34-2

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生物活性

D-Tetramannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Tetramannuronic acid can be used for the research of pain and vascular dementia[1][2][3][4].

分子量

722.51

Formula

C24H34O25
CAS 号

149511-34-2
中文名称

D-甘露糖醛酸四糖
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Heyraud A, et, al. HPLC analysis of saturated or unsaturated oligoguluronates and oligomannuronates. Application to the determination of the action pattern of Haliotis tuberculata alginate lyase. Carbohydr Res. 1996 Sep 23; 291:115-26.

    [2]. Iwamoto M, et, al. Structure-activity relationship of alginate oligosaccharides in the induction of cytokine production from RAW264.7 cells. FEBS Lett. 2005 Aug 15; 579(20): 4423-9.

    [3]. Geng M, et, al. Application of sodium alginate oligose and derivative to treatment of pain. CN106344595A.

    [4]. Geng M, et, al. Application of sodium alginate oligose and derivative to treatment of vascular dementia. CN106344593A.

8-Epiloganic acid

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天然产物 糖类和糖苷 Saccharides and Glycosides

8-Epiloganic acid;

8-Epiloganic acid 是一种环烯醚萜苷，可从 Linaria cymbalaria (玄参科) 中分离得到。

8-Epiloganic acid

8-Epiloganic acid Chemical Structure

CAS No. : 82509-41-9

规格 价格 是否有货 数量
5 mg ￥4600 In-stock
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8-Epiloganic acid 相关产品

bull;相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Natural Product Library
  • Glycoside Compound Library
  • Traditional Chinese Medicine Monomer Library

生物活性

8-Epiloganic acid, an iridoid glucoside, can be found in Linaria cymbalaria (Scrophulariaceae)[1].

分子量

376.36

Formula

C16H24O10
CAS 号

82509-41-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4deg;C, sealed storage, away from moisture and light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)
参考文献

  • [1]. Bianco A, et, al. 8-epiloganic acid and 7-beta-hydroxy-8-epiiridodial glucoside. Planta Med. 1982 Sep;46(1):38-41.

Pseudolaric acid A-O-β-D-glucopyranoside

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天然产物 糖类和糖苷 Saccharides and Glycosides

Pseudolaric acid A-O-β-D-glucopyranoside;

Pseudolaric acid A-O-β-D-glucopyranoside 是从Cortex Pseudolaricis 中分离得到的一种土槿乙酸，具有抗真菌和避孕活性。

Pseudolaric acid A-O-β-D-glucopyranoside

Pseudolaric acid A-O-β-D-glucopyranoside Chemical Structure

CAS No. : 98891-44-2

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生物活性

Pseudolaric acid A-O-β-D-glucopyranoside, isolated from Cortex Pseudolaricis, demonstrates antifungal and antifertility activities[1].

分子量

550.59

Formula

C28H38O11
CAS 号

98891-44-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Han QB, et al. Rapid analysis of pseudolaric acids in Cortex Pseudolaricis and related medicinal products by high performance liquid chromatography. Talanta. 2007 Oct 15;73(4):757-63.

L-Hexaguluronic acid(Synonyms: L-古罗糖醛酸五糖)

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天然产物 糖类和糖苷 Saccharides and Glycosides

L-Hexaguluronic acid;(Synonyms: L-古罗糖醛酸五糖)

L-Hexaguluronic acid 是一种由 6 个 L-guluronic acid (G) 组成的直链多糖共聚物。

L-Hexaguluronic acid(Synonyms: L-古罗糖醛酸五糖)

L-Hexaguluronic acid Chemical Structure

CAS No. : 183668-74-8

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1 mg ￥1400 询问价格 货期

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生物活性

L-Hexaguluronic acid is a linear polysaccharide copolymer composed of six L-guluronic acid (G)[1].

分子量

1074.76

Formula

C36H50O37
CAS 号

183668-74-8
中文名称

L-古罗糖醛酸五糖
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. R.A. Shirwaiker, et al. L-Guluronic Acid

L-Pentaguluronic acid(Synonyms: L-古罗糖醛酸五糖)

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天然产物 糖类和糖苷 Saccharides and Glycosides

L-Pentaguluronic acid;(Synonyms: L-古罗糖醛酸五糖)

L-Pentaguluronic acid 是一种由 5 个 L-guluronic acid (G) 组成的直链多糖共聚物。

L-Pentaguluronic acid(Synonyms: L-古罗糖醛酸五糖)

L-Pentaguluronic acid Chemical Structure

CAS No. : 183668-72-6

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生物活性

L-Pentaguluronic acid is a linear polysaccharide copolymer composed of four L-guluronic acid (G)[1].

分子量

898.64

Formula

C30H42O31
CAS 号

183668-72-6
中文名称

L-古罗糖醛酸五糖
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. R.A. Shirwaiker, et al. L-Guluronic Acid

2-Naphthalenecarboxylic acid, 4-(D-glucopyranosyloxy)-1-hydroxy-3-(3-hydroxy-3-methylbutyl)-, methyl ester

发表于由

天然产物 糖类和糖苷 Saccharides and Glycosides

2-Naphthalenecarboxylic acid, 4-(D-glucopyranosyloxy)-1-hydroxy-3-(3-hydroxy-3-methylbutyl)-, methyl ester;

2-Naphthalenecarboxylic acid, 4-(D-glucopyranosyloxy)-1-hydroxy-3-(3-hydroxy-3-methylbutyl)-, methyl ester (compound 3) 是一种天然产物，可以从 Rubia cordifolia 的根中提取得到。

2-Naphthalenecarboxylic acid, 4-(D-glucopyranosyloxy)-1-hydroxy-3-(3-hydroxy-3-methylbutyl)-, methyl ester

2-Naphthalenecarboxylic acid, 4-(D-glucopyranosyloxy)-1-hydroxy-3-(3-hydroxy-3-methylbutyl)-, methyl ester Chemical Structure

CAS No. : 125906-48-1

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生物活性

2-Naphthalenecarboxylic acid, 4-(D-glucopyranosyloxy)-1-hydroxy-3-(3-hydroxy-3-methylbutyl)-, methyl ester (compound 3) is a natural product that can be isolated from the dried roots of Rubia cordifolia[1].

分子量

466.48

Formula

C23H30O10
CAS 号

125906-48-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Hideji Itokawa, et al. Anthraquinones and naphthohydroquinones from Rubia cordifolia. Phytochemistry, 1989. 28(12), 3465-3468.

Oxytocin free acid(Synonyms: 9-Deamidooxytocin)

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Oxytocin free acid;(Synonyms: 9-Deamidooxytocin)

Oxytocin free acid (9-Deamidooxytocin) 是催产素的类似物，其 9 位的甘氨酸残基被甘氨酸残基取代。Oxytocin 是一种多效性肽类激素，对一般健康、适应、发育、生殖和社会行为有广泛的影响。

Oxytocin free acidamp;;(Synonyms: 9-Deamidooxytocin)

Oxytocin free acid Chemical Structure

CAS No. : 4248-64-0

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生物活性

Oxytocin free acid (9-Deamidooxytocin) is an analog of oxytocin in which the glycinamide residue at position 9 in oxytocin has been replaced by a glycine residue. Oxytocin is a pleiotropic, peptide hormone with broad implications for general health, adaptation, development, reproduction, and social behavior[1][2].

分子量

1008.17

Formula

C43H65N11O13S2
CAS 号

4248-64-0
Sequence Shortening

CYIQNCPLG (Disulfide bridge:Cys1-Cys6)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Ferrier BM, et al. 9-Deamidooxytocin, an analog of the hormone containing a glycine residue in place of the glycinamide residue. J Med Chem. 1966;9(1):55-57.

    [2]. Carter CS, Kenkel WM, MacLean EL, et al. Is Oxytocin “Nature’s Medicine”?. Pharmacol Rev. 2020;72(4):829-861.

Amlodipine aspartic acid impurity(Synonyms: Amlodipine aspartate)

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Amlodipine aspartic acid impurity;(Synonyms: Amlodipine aspartate)

Amlodipine aspartic acid impurity 是 Amlodipine aspartic acid 的杂质。Amlodipine aspartic acid 是一种钙通道阻滞剂，具有抗高血压和抗心脏病的特性。

Amlodipine aspartic acid impurityamp;;(Synonyms: Amlodipine aspartate)

Amlodipine aspartic acid impurity Chemical Structure

CAS No. : 400602-35-9

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生物活性

Amlodipine aspartic acid impurity is the impurity of Amlodipine aspartic acid. Amlodipine aspartic acid is a calcium channel blocker with antihypertensive and antianginal properties.

分子量

524.95

Formula

C24H29ClN2O9
CAS 号

400602-35-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Sheraz MA, et al. Formulations of Amlodipine: A Review. J Pharm (Cairo). 2016;2016:8961621.

Caffeic acid-pYEEIE

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Caffeic acid-pYEEIE;

Caffeic acid-pYEEIE 是一种非磷酸肽抑制剂，对 GST-Lck-SH2 结构域具有强大的结合亲和力。

Caffeic acid-pYEEIEamp;;

Caffeic acid-pYEEIE Chemical Structure

CAS No. : 507471-72-9

规格 是否有货
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生物活性

Caffeic acid-pYEEIE, a non-phosphopeptide inhibitor, exhibits potent binding affinity for the GST-Lck-SH2 domain[1].

分子量

923.81

Formula

C39H50N5O19P
CAS 号

507471-72-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. See-Hyoung Park, et al. Design and characterization of non-phosphopeptide inhibitors for Src family SH2 domains. Bioorg Med Chem Lett. 2002 Oct 7;12(19):2711-4.