NLS-StAx-h;
NLS-StAx-h 是选择性的 Wnt 信号传导的固定肽抑制剂，IC50 为 1.4 μM。NLS-StAx-h 有效抑制 β-catenin-转录因子的相互作用。NLS-StAx-h 抑制结直肠癌细胞的增殖和迁移。
NLS-StAx-h Chemical Structure
| 规格 | 是否有货 | ||
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| 100 μg | 询价 |
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| 生物活性 |
NLS-StAx-h is a selective, stapled peptide inhibitor of Wnt signaling with an IC50 of 1.4 μM. NLS-StAx-h efficiently inhibits β-catenin-transcription factor interactions. NLS-StAx-h inhibits proliferation and migration of colorectal cancer cells[1]. |
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| IC50 Target[1] |
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| 体外研究 (In Vitro) |
NLS-StAx-h (10 μM, 72 hr) reduces the viability of both SW-480 and DLD-1 by more than 80%. NLS-StAx-h results in gene expression changes[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
3445.26 |
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| Formula |
C53H100N19O10V2W |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| 参考文献 |
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