tcY-NH2(Synonyms: (trans-Cinnamoyl)-YPGKF-NH2)

发表于由

tcY-NH2;(Synonyms: (trans-Cinnamoyl)-YPGKF-NH2)

tcY-NH2 是选择性的 PAR4 肽类拮抗剂。tcY-NH2 抑制凝血酶和 AY-NH2 诱导的大鼠血小板聚集。

tcY-NH2amp;;(Synonyms: (trans-Cinnamoyl)-YPGKF-NH2)

tcY-NH2 Chemical Structure

CAS No. : 327177-34-4

规格 是否有货
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生物活性

tcY-NH2 is a selective PAR4 antagonist peptide. tcY-NH2 inhibits thrombin- and AY-NH2-induced rat platelet aggregation[1][2].

分子量

739.86

Formula

C40H49N7O7
CAS 号

327177-34-4
Sequence Shortening

{trans-Cinnamoyl}-YPGKF-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Morley D Hollenberg, et al. Proteinase-activated receptor-4: evaluation of tethered ligand-derived peptides as probes for receptor function and as inflammatory agonists in vivo. Br J Pharmacol. 2004 Oct;143(4):443-54.

    [2]. L Ma, et al. Thrombin-induced platelet endostatin release is blocked by a proteinase activated receptor-4 (PAR4) antagonist. Br J Pharmacol. 2001 Oct;134(4):701-4.