β-Amyloid (1-9)

发表于由

β-Amyloid (1-9);

β-Amyloid (1-9)，β- 淀粉样蛋白的一个 N 端片段，由氨基酸残基 1 到 9 组成。β-Amyloid (1-9) 含有 B 细胞表位，但不包括 T 细胞表位。在全长阿尔茨海默病 β- 淀粉样肽 (1-40) 中, 1 到 9 的缺失不能阻止其形成淀粉样纤维或消除纤维多态性。

β-Amyloid (1-9)amp;;

β-Amyloid (1-9) Chemical Structure

CAS No. : 147529-30-4

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生物活性

β-Amyloid (1-9), an N-terminal fragment of beta amyloid, consists of amino acid residues 1 to 9. β-Amyloid (1-9) contains a B cell epitope, but it does not include T cell epitopes. Omission of residues 1 to 9 from the full-length Alzheimer’sβ-Amyloid peptide 1 to 40 does not prevent the peptide from forming amyloid fibrils or eliminate fibril polymorphism [1][2].

分子量

1033.01

Formula

C42H60N14O17
CAS 号

147529-30-4
Sequence

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly
Sequence Shortening

DAEFRHDSG
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zamora E, et al. Papillomavirus-like particles are an effective platform for amyloid-beta immunization in rabbitsand transgenic mice. J Immunol. 2006 Aug 15;177(4):2662-2670.

    [2]. Paravastu AK, et al. Polymorphic fibril formation by residues 10-40 of the Alzheimer’s beta-amyloid peptide. Biophys J. 2006 Jun 15;90(12):4618-29.