Glabranine(Synonyms: 光甘草宁；欧亚甘草宁；裸禾蕨黄素)

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天然产物 黄酮类 Flavonoids

Glabranine (Synonyms: 光甘草宁；欧亚甘草宁；裸禾蕨黄素)

Glabranine 是从 Tephrosia s.p 中分离出一种类黄酮，在体外对登革病毒发挥抑制作用。 Glabranine 与 DENV 2 型 (DENV2) E 蛋白的可溶性胞外域形成相互作用。

Glabranine(Synonyms: 光甘草宁；欧亚甘草宁；裸禾蕨黄素)

Glabranine Chemical Structure

CAS No. : 41983-91-9

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生物活性

Glabranine, an flavonoid, is isolated from Tephrosia s.p, exerts a inhibitory effect in vitro on the dengue virus[1]. Glabranine forms interaction with the soluble ectodomain of DENV type 2 (DENV2) E protein[2].

分子量

324.37

Formula

C20H20O4
CAS 号

41983-91-9
中文名称

光甘草宁；欧亚甘草宁；裸禾蕨黄素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Sánchez I, et al. Antiviral effect of flavonoids on the dengue virus. Phytother Res. 2000 Mar;14(2):89-92.

    [2]. Ismail NA, et al. Molecular Docking and Molecular Dynamics Simulation Studies to Predict Flavonoid Binding on the Surface of DENV2 E Protein. Interdiscip Sci. 2017 Dec;9(4):499-511.