Platyconic acid A

发表于由

天然产物 糖类和糖苷 Saccharides and Glycosides

Platyconic acid A; 纯度: 99.08%

Platyconic Acid A 是桔梗皂苷的活性成分，可用于减轻气道炎症的研究。

Platyconic acid A

Platyconic acid A Chemical Structure

CAS No. : 68051-23-0

规格 价格 是否有货 数量
5 mg ￥4000 In-stock
10 mg ; 询价 ;
50 mg ; 询价 ;

* Please select Quantity before adding items.

Platyconic acid A 相关产品

bull;相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Immunology/Inflammation Compound Library
  • Natural Product Library
  • Glycoside Compound Library
  • Medicine Food Homology Compound Library

生物活性

Platyconic Acid A is an active component of changkil saponins from platycodon grandiflorum and can be used for the research of reducing airway inflammation[1].

体外研究
(In Vitro)

Platyconic Acid A (0.5~2 μM; 30 minutes; A549 cells) inhibits PMA-induced NF-κB p65 phosphorylation, IκBα phosphorylation and degradation and Akt phosphorylation in a concentration-dependent manner[1].
Platyconic Acid A (0.5~2 μM; 24 hours; A549 cells) decreases PMA-increased MUC5AC mRNA expression in a concentration-dependent manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: A549 cells
Concentration: 0.5~2 μM
Incubation Time: 30 minutes
Result: Inhibited PMA-induced NF-κB p65 phosphorylation, IκBα phosphorylation and degradation and Akt phosphorylation in a concentration-dependent manner.

RT-PCR[1]

Cell Line: A549 cells
Concentration: 0.5~2 μM
Incubation Time: 24 hours
Result: Decreased PMA-increased MUC5AC mRNA expression in a concentration-dependent manner.

分子量

1239.31

Formula

C57H90O29
CAS 号

68051-23-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4deg;C, protect from light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)
溶解性数据
In Vitro:;

H2O : 25 mg/mL (20.17 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.8069 mL 4.0345 mL 8.0690 mL
5 mM 0.1614 mL 0.8069 mL 1.6138 mL
10 mM 0.0807 mL 0.4035 mL 0.8069 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Choi JH, et al. Saponins, especially platyconic acid A, from Platycodon grandiflorum reduce airway inflammation in ovalbumin-induced mice and PMA-exposed A549 cells. J Agric Food Chem. 2015;63(5):1468-1476.