Thymalfasin(Synonyms: 胸腺法新 Thymosin α1)

Thymalfasin;(Synonyms: 胸腺法新; Thymosin α1) 纯度: 99.83%

Thymalfasin (thymosin-alpha 1) 是一个免疫调节化合物,能够提高 Thl 的免疫应答。

Thymalfasinamp;;(Synonyms: 胸腺法新; Thymosin α1)

Thymalfasin Chemical Structure

CAS No. : 62304-98-7

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1 mg ¥1600 In-stock
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10 mg ¥8600 In-stock
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Thymalfasin 相关产品

bull;相关化合物库:

  • Drug Repurposing Compound Library Plus
  • FDA-Approved Drug Library Plus
  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Thymalfasin is an immunomodulating agent able to enhance the Thl immune response.

体外研究
(In Vitro)

Thymalfasin has been shown to have efficacy in multiple experimental models of immune dysfunction, mainly, infectious diseases such as hepatitis (woodchuck) and influenza (mouse), and cancer such as melanoma (mouse) and colorectal carcinoma (rat) where thymalfasin has shown antitumor effects[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Thymalfasin has been shown to have efficacy in multiple experimental models of immune dysfunction, mainly, infectious diseases such as hepatitis (woodchuck) and influenza (mouse), and cancer such as melanoma (mouse) and colorectal carcinoma (rat) where thymalfasin has shown antitumor effects[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

分子量

3108.28

Formula

C129H215N33O55

CAS 号

62304-98-7

Sequence

N-acetyl-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn

Sequence Shortening

Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN

中文名称

胸腺法新

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -80deg;C 2 years
-20deg;C 1 year
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

H2O : 0.3 mg/mL (0.10 mM; Need ultrasonic and warming)

参考文献
  • [1]. Lao X et al. A modified thymosin alpha 1 inhibits the growth of breast cancer both in vitro and in vivo: suppressment of cell proliferation, inducible cell apoptosis and enhancement of targeted anticancer effects. Apoptosis. 2015 Oct;20(10):1307-20.

    [2]. Sjogren MH et al. Thymalfasin: an immune system enhancer for the treatment of liver disease. J Gastroenterol Hepatol. 2004 Dec;19(12):S69-72.