Sanguisorbigenin(Synonyms: 地榆皂苷元)

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上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Sanguisorbigenin (Synonyms: 地榆皂苷元)

Sanguisorbigenin 是一种天然抗菌剂，可抑制耐甲氧西林金黄色葡萄球菌 (MRSA)。

Sanguisorbigenin(Synonyms: 地榆皂苷元)

Sanguisorbigenin Chemical Structure

CAS No. : 6812-98-2

规格 价格 是否有货
5 mg ￥8000 询问价格 & 货期
10 mg ￥12800 询问价格 & 货期

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生物活性

Sanguisorbigenin is a natural antibacterial agent that inhibits methicillin-resistant S. aureus (MRSA)[1].

体外研究
(In Vitro)

The minimal inhibitory concentration values of Sanguisorbigenin against six strains of S. aureus are in the range of 12.5-50 μg/mL[1].
The expression of blaR1, mecA and blaZ is significantly inhibited in MRSA in a dose-dependent manner when it is treated with sub-MIC (1.56-6.25 μg/mL) concentrations of Sanguisorbigenin. Sanguisorbigenin remarkably reduces the gene expression of mecA. Sanguisorbigenin has a potent antibacterial effect and could effectively reverse the sense of antibiotics by inhibiting the mecA expression and decrease PBP2a expression[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

454.68

Formula

C30H46O3
CAS 号

6812-98-2
中文名称

地榆皂苷元
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. S Wang, et al. Antibacterial activity and synergy of antibiotics with sanguisorbigenin isolated from Sanguisorba officinalis L. against methicillin-resistant Staphylococcus aureus. Lett Appl Microbiol. 2021 Mar;72(3):238-244.