S961 TFA;
S961 TFA 是一种高亲和力的胰岛素受体 (insulin receptor, IR) 拮抗剂，对 HIR-A，HIR-B 和人胰岛素样生长因子 I 受体 (HIGF-IR) 的 IC50 分别为 0.048，0.027 和 630 nM。
S961 TFA Chemical Structure
| 规格 | 价格 | 是否有货 | |
|---|---|---|---|
| 1 mg | ￥5500 | 询问价格 & 货期 | |
| 5 mg | ￥15000 | 询问价格 & 货期 | |
| 10 mg | ￥25000 | 询问价格 & 货期 | |
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S961 TFA 的其他形式现货产品:
| 生物活性 |
S961 TFA is an high-affinity and selective insulin receptor (IR) antagonist with IC50s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively[1]. |
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| 体外研究 (In Vitro) |
S961 also shows high-affinity to Rat IR and Pig IR with IC50s of 0.056 nM and 0.084 nM in PEG-assay, respectively[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
4918.15 |
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| Formula |
C211H297N55O71S2.C2HF3O2 |
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| Sequence |
Gly-Ser-Leu-Asp-Glu-Ser-Phe-Tyr-Asp-Trp-Phe-Glu-Arg-Gln-Leu-Gly-Gly-Gly-Ser-Gly-Gly-Ser-Ser-Leu-Glu-Glu-Glu-Trp-Ala-Gln-Ile-Gln-Cys-Glu-Val-Trp-Gly-Arg-Gly-Cys-Pro-Ser-Tyr (Disulfide bridge: Cys33-Cys40) |
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| Sequence Shortening |
GSLDESFYDWFERQLGGGSGGSSLEEEWAQIQCEVWGRGCPSY (Disulfide bridge: Cys33-Cys40) |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
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| 溶解性数据 |
In Vitro:;
H2O : 6.5 mg/mL (1.32 mM; ultrasonic and adjust pH to 12 with NaOH) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
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| 参考文献 |
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