天然产物 黄酮类 Flavonoids
Nepetin (Synonyms: 6-Methoxyluteolin) 纯度: 99.51%
Nepetin (6-Methoxyluteolin) 是从 Eupatorium ballotaefolium HBK 分离的天然类黄酮,具有有效的抗炎活性。Nepetin 在 ARPE-19 细胞中抑制 IL-6,IL-8 和 MCP-1 分泌,IC50 值分别为 4.43 μM、3.42 μM 和 4.17 μM。
Nepetin Chemical Structure
CAS No. : 520-11-6
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥4030 | In-stock | |
10 mg | ¥6860 | In-stock | |
50 mg | 询价 | ||
100 mg | 询价 |
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Nepetin 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Immunology/Inflammation Compound Library
- Natural Product Library
- Phenols Library
- Pyroptosis Compound Library
- Traditional Chinese Medicine Monomer Library
- Flavonoids Library
- Food-Sourced Compound Library
生物活性 |
Nepetin (6-Methoxyluteolin) is a natural flavonoid isolated from Eupatorium ballotaefolium HBK with potent anti-inflammatory activities. Nepetin inhibits IL-6, IL-8 and MCP-1 secretion with IC50 values of 4.43 μM, 3.42 μM and 4.17 μM, respectively in ARPE-19 cells[1][2]. |
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体外研究 (In Vitro) |
Pretreatment with Nepetin dose-dependently inhibited IL-6, IL-8 and MCP-1 secretion with IC50 values of 4.43, 3.42 and 4.17 μM, respectively[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. RT-PCR[1]
Western Blot Analysis[1]
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分子量 |
316.26 |
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Formula |
C16H12O7 |
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CAS 号 |
520-11-6 |
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中文名称 |
泽兰黄酮 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
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溶解性数据 |
In Vitro:
DMSO : 250 mg/mL (790.49 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
*以上所有助溶剂都可在 Shanghai Jinpan Biotech Co Ltd 网站选购。
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参考文献 |
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