Epibetulinic acid(Synonyms: 表白桦脂酸)

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Epibetulinic acid (Synonyms: 表白桦脂酸)

Epibetulinic acid 作用于用细菌内毒素刺激的小鼠巨噬细胞 (RAW 264.7),抑制 NO 和前列腺素 E2 (PGE2) 产生,IC50 分别为 0.7 和 0.6 μM。具有抗炎活性。

Epibetulinic acid(Synonyms: 表白桦脂酸)

Epibetulinic acid Chemical Structure

CAS No. : 38736-77-5

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生物活性

Epibetulinic acid exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC50s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity[1].

IC50 & Target[1]

PGE2

0.6 μM (IC50)

NO

0.7 μM (IC50)

分子量

456.70

Formula

C30H48O3

CAS 号

38736-77-5

中文名称

表白桦脂酸

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Reyes CP, et al. Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2. Bioorg Med Chem. 2006 Mar 1;14(5):1573-9.