天然产物 天然产物苯丙素类 Phenylpropanoids
Eleutheroside B1 纯度: ≥98.0%
Eleutheroside B1，香豆素化合物，具有广谱的抗人流感病毒 (influenza virus) 作用，其IC50 值为 64-125μg/ml。Eleutheroside B1 通过 POLR2A 和 N-糖基化介导其抗流感活性。Eleutheroside B1 抑制多种趋化因子基因和流感病毒核蛋白 (NP) 基因的 mRNA 表达，且具有较低的细胞毒性。具有抗病毒、抗炎活性。
Eleutheroside B1 Chemical Structure
CAS No. : 16845-16-2
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 1 mg | ￥2500 | In-stock | |
| 5 mg | ￥5500 | In-stock | |
| 10 mg | 询价 | ||
| 50 mg | 询价 |
* Please select Quantity before adding items.
Eleutheroside B1 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
| 生物活性 |
Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities[1]. |
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| 体外研究 (In Vitro) |
Eeutheroside B1 (100 µg/ml; 24 hours) influences mRNA expression of host genes and virus genes in A549 cells[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. RT-PCR[1]
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| 分子量 |
384.33 |
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| Formula |
C17H20O10 |
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| CAS 号 |
16845-16-2 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
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| 参考文献 |
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