Sphondin(Synonyms: 牛防风素)

天然产物 天然产物苯丙素类 Phenylpropanoids

Sphondin (Synonyms: 牛防风素)

Sphondin 对 IL-1β 诱导的 A549 细胞中 COX-2 蛋白和 PGE2 释放水平的升高具有抑制作用。

Sphondin(Synonyms: 牛防风素)

Sphondin Chemical Structure

CAS No. : 483-66-9

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生物活性

Sphondin possesses an inhibitory effect on IL-1β-induced increase in the level of COX-2 protein and PGE2 release in A549 cells[1].

IC50 & Target[1]

COX-2

 

体外研究
(In Vitro)

Pretreatment of A549 cells with Sphondin (10-50 μM) concentration-dependently attenuates IL-1β-induced COX-2 protein expression and PGE2 release[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

216.19

Formula

C12H8O4

CAS 号

483-66-9

中文名称

牛防风素

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Ling Ling Yang, et al. Effects of Sphondin, Isolated From Heracleum Laciniatum, on IL-1beta-induced cyclooxygenase-2 Expression in Human Pulmonary Epithelial Cells. Life Sci. 2002 Nov 29;72(2):199-213.