GPRP acetate(Synonyms: Gly-Pro-Arg-Pro acetate Pefa 6003 acetate)

发表于由

GPRP acetate;(Synonyms: Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate) 纯度: 99.83%

GPRP acetate (Gly-Pro-Arg-Pro acetate) 是一种纤维蛋白聚合抑制剂, 能够抑制纤维蛋白原与血小板膜糖蛋白 Ⅱb/IIIa 复合物(糖蛋白 IIb/IIIa 受体)之间的相互作用。

GPRP acetateamp;;(Synonyms: Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate)

GPRP acetate Chemical Structure

CAS No. : 157009-81-9

规格 价格 是否有货 数量
1 mg ￥2200 In-stock
5 mg ￥5000 In-stock
10 mg ; 询价 ;
50 mg ; 询价 ;

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GPRP acetate 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptidomimetic Library
  • Peptide Library

生物活性

GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa)[1][2].

分子量

485.53

Formula

C20H35N7O7
CAS 号

157009-81-9
Sequence

Gly-Pro-Arg-Pro
Sequence Shortening

GPRP
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro:;

H2O : 125 mg/mL (257.45 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.0596 mL 10.2980 mL 20.5961 mL
5 mM 0.4119 mL 2.0596 mL 4.1192 mL
10 mM 0.2060 mL 1.0298 mL 2.0596 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Gallistl S, et al. Gly-pro-arg-pro (GPRP) enhances free thrombin. Thromb Res. 1995 Jun 15;78(6):547-50.

    [2]. Hsieh KH, et, al. Fibrin Polymerization. 1. Alkylating peptide inhibitors of fibrin polymerization. J Med Chem. 1981 Mar; 24(3): 322-7.