标签归档：pro

[D-Arg1, D-Pro2, D-Trp7,9, Leu11]-Substance P 品牌：FUJIFILM Wako

发表于由

[D-Arg1, D-Pro2, D-Trp7,9, Leu11]-Substance P

品牌：FUJIFILM Wako
CAS No.：84676-91-5
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

013-22973

 for Proteome Research 2 nmol×5本 –

[D-Arg1, D-Pro2, D-Trp7,9, Leu11]-Substance P 品牌：FUJIFILM Wako

 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

[Leu31,Pro34]-Neuropeptide Y(human,rat)

发表于由

[Leu31,Pro34]-Neuropeptide Y(human,rat);

[Leu31,Pro34]-Neuropeptide Y(human,rat) 是一种特定的神经肽 Y Y1 受体激动剂。[Leu31,Pro34]-Neuropeptide Y(human,rat) 也激活 Y4，Y5。[Leu31,Pro34]-Neuropeptide Y(human,rat) 可以增加麻醉大鼠的血压，也增加饮食摄入量。

[Leu31,Pro34]-Neuropeptide Y(human,rat)amp;;

[Leu31,Pro34]-Neuropeptide Y(human,rat) Chemical Structure

CAS No. : 132699-73-1

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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[Leu31,Pro34]-Neuropeptide Y(human,rat) 的其他形式现货产品:

[Leu31,Pro34]-Neuropeptide Y(human,rat) TFA

生物活性

[Leu31,Pro34]-Neuropeptide Y(human,rat) is a specific neuropeptide Y Y1 receptor agonist. [Leu31,Pro34]-Neuropeptide Y(human,rat) slao activates Y4, Y5. [Leu31,Pro34]-Neuropeptide Y(human,rat) can increase blood pressure in anesthetized rats and increases food intake[1][2].

IC50 Target[1][2]

NPY Y1 receptor

;

NPY Y4 receptor

;

NPY Y5 receptor

;

体外研究
(In Vitro)

[Leu31,Pro34]-Neuropeptide Y(human,rat) has Ki values of 0.39 nM, 0.499 nM, 0.31 nM for Y1, Y4, Y5 in HEK cell lines. [Leu31,Pro34]-Neuropeptide Y(human,rat) has a Ki of >1000 for Y2 in HEK cell lines[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

[Leu31,Pro34]-Neuropeptide Y(human,rat) (30 pmol; microinjected into paraventricular nucleus) increases food intake in the rats (350±400 g)[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

4240.73

Formula

C189H284N54O56S
CAS 号

132699-73-1
Sequence

Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2
Sequence Shortening

YPSKPDNPGEDAPAEDMARYYSALRHYINLLTRPRY-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. J Fuhlendorff, et al. [Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist. Proc Natl Acad Sci U S A. 1990 Jan;87(1):182-6.

    [2]. K McCrea, et al. 2-36[K4,RYYSA(19-23)]PP a novel Y5-receptor preferring ligand with strong stimulatory effect on food intake. Regul Pept. 2000 Feb 8;87(1-3):47-58.

    [3]. A Kask, et al. Evidence for involvement of neuropeptide Y receptors in the regulation of food intake: studies with Y1-selective antagonist BIBP3226. Br J Pharmacol. 1998 Aug;124(7):1507-15.

GPRP(Synonyms: Gly-Pro-Arg-Pro Pefa 6003)

发表于由

GPRP;(Synonyms: Gly-Pro-Arg-Pro; Pefa 6003)

GPRP 是一种纤维蛋白聚合抑制剂，能够抑制纤维蛋白原与血小板膜糖蛋白 Ⅱb/IIIa 复合物(糖蛋白 IIb/IIIa 受体)之间的相互作用。

GPRPamp;;(Synonyms: Gly-Pro-Arg-Pro; Pefa 6003)

GPRP Chemical Structure

CAS No. : 67869-62-9

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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GPRP 的其他形式现货产品:

GPRP acetate

生物活性

GPRP (Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa)[1][2].

分子量

425.48

Formula

C18H31N7O5
CAS 号

67869-62-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Gallistl S, et al. Gly-pro-arg-pro (GPRP) enhances free thrombin. Thromb Res. 1995 Jun 15;78(6):547-50.

    [2]. Hsieh KH, et, al. Fibrin Polymerization. 1. Alkylating peptide inhibitors of fibrin polymerization. J Med Chem. 1981 Mar; 24(3): 322-7.

[D-Arg1, D-Pro2, D-Trp7,9, Leu11]-Substance P 品牌：FUJIFILM Wako

发表于由

[D-Arg1, D-Pro2, D-Trp7,9, Leu11]-Substance P

品牌：FUJIFILM Wako
CAS No.：84676-91-5
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

017-22971

 for Proteome Research 2 nmol本 –

[D-Arg1, D-Pro2, D-Trp7,9, Leu11]-Substance P 品牌：FUJIFILM Wako

 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

pGlu-Pro-Arg-MNA

发表于由

pGlu-Pro-Arg-MNA;

pGlu-Pro-Arg-MNA 是一种显色底物。

pGlu-Pro-Arg-MNAamp;;

pGlu-Pro-Arg-MNA Chemical Structure

CAS No. : 130835-45-9

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

pGlu-Pro-Arg-MNA 的其他形式现货产品:

pGlu-Pro-Arg-MNA monoacetate

生物活性

pGlu-Pro-Arg-MNA is a chromogenic substrate.

体外研究
(In Vitro)

Protein C activity is measured using the reagents, both with a partial thromboplastin time (aPTT) system as well as with a chromogenic substrate (pGlu-Pro-Arg-mNA) in a photometric method[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

532.55

Formula

C23H32N8O7
CAS 号

130835-45-9
Sequence

{pGlu}-Pro-Arg-MNA
Sequence Shortening

{pGlu}-PR-MNA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Girolami A, et al. Heterozygous protein-S deficiency: a study of a large kindred. Acta Haematol. 1990;84(3):162-8.

Pro-Phe-Phe

发表于由

Pro-Phe-Phe;

Pro-Phe-Phe 是最容易聚集的天然氨基酸三肽。Pro-Phe-Phe 形成独特的螺旋状薄片，通过芳香族干界面相配合。Pro-Phe-Phe 可用于模块化超螺旋自组装纳米结构的设计。

Pro-Phe-Pheamp;;

Pro-Phe-Phe Chemical Structure

CAS No. : 164257-32-3

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Pro-Phe-Phe is the most aggregation-prone tripeptide of natural amino acids. Pro-Phe-Phe forms unique helical-like sheets that mate via aromatic dry interfaces. Pro-Phe-Phe can be used for the design of modular super-helical self-assembling nanostructures[1][2].

分子量

409.48

Formula

C23H27N3O4
CAS 号

164257-32-3
Sequence

Pro-Phe-Phe
Sequence Shortening

PFF
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Bera S, et, al. Rigid helical-like assemblies from a self-aggregating tripeptide. Nat Mater. 2019 May;18(5):503-509.

    [2]. Bera S, et, al. Rigid helical-like assemblies from a self-aggregating tripeptide. Nat Mater. 2019 May;18(5):503-509.

D-Lys(Z)-Pro-Arg-pNA(Synonyms: Chromozym Pca)

发表于由

D-Lys(Z)-Pro-Arg-pNA;(Synonyms: Chromozym Pca)

D-Lys(Z)-Pro-Arg-pNA (Chromozym Pca) 是 APC (活化蛋白 C ) 的发光底物。

D-Lys(Z)-Pro-Arg-pNAamp;;(Synonyms: Chromozym Pca)

D-Lys(Z)-Pro-Arg-pNA Chemical Structure

CAS No. : 108963-69-5

规格 是否有货
5 mg 询价
10 mg 询价
50 mg 询价
100 mg 询价

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生物活性

D-Lys(Z)-Pro-Arg-pNA (Chromozym Pca) is a luminescent substrate of activated protein C (APC).

分子量

653.73

Formula

C31H43N9O7
CAS 号

108963-69-5
Sequence

{d-Lys(Z)}-Pro-Arg-pNA
Sequence Shortening

{d-Lys(Z)}-PR-pNA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

pGlu-Pro-Arg-MNA monoacetate

发表于由

pGlu-Pro-Arg-MNA monoacetate; 纯度: ge;99.0%

pGlu-Pro-Arg-MNA monoacetate 是一种显色底物。

pGlu-Pro-Arg-MNA monoacetateamp;;

pGlu-Pro-Arg-MNA monoacetate Chemical Structure

CAS No. : 2070009-26-4

规格 价格 是否有货 数量
10;mM;*;1 mL in Water ￥4563 In-stock
5 mg ￥3500 In-stock
10 mg ￥5000 In-stock
50 mg ￥15000 In-stock
100 mg ; 询价 ;
200 mg ; 询价 ;

* Please select Quantity before adding items.

pGlu-Pro-Arg-MNA monoacetate 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

pGlu-Pro-Arg-MNA monoacetate is a chromogenic substrate.

体外研究
(In Vitro)

Protein C activity is measured using the reagents, both with a partial thromboplastin time (aPTT) system as well as with a chromogenic substrate (pGlu-Pro-Arg-mNA) in a photometric method[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

592.60

Formula

C25H36N8O9
CAS 号

2070009-26-4
Sequence

{pGlu}-Pro-Arg-MNA
Sequence Shortening

{pGlu}-PR-MNA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro:;

H2O : ≥ 25 mg/mL (42.19 mM)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.6875 mL 8.4374 mL 16.8748 mL
5 mM 0.3375 mL 1.6875 mL 3.3750 mL
10 mM 0.1687 mL 0.8437 mL 1.6875 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Girolami A, et al. Heterozygous protein-S deficiency: a study of a large kindred. Acta Haematol. 1990;84(3):162-8.

His-Pro

发表于由

His-Pro;

His-Pro 是一种由组氨酰和脯氨酸组成的二肽。

His-Proamp;;

His-Pro Chemical Structure

CAS No. : 20930-58-9

规格 价格 是否有货
10 mg ￥950 询问价格 货期

* Please select Quantity before adding items.

生物活性

His-Pro is a dipeptide consisting of histidyl and proline.

分子量

252.27

Formula

C11H16N4O3
CAS 号

20930-58-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Park SW, et al. Alterations in pancreatic protein expression in STZ-induced diabetic rats and genetically diabetic mice in response to treatment with hypoglycemic dipeptide Cyclo (His-Pro). Cell Physiol Biochem. 2012;29(3-4):603-16.

His-Pro hydrochloride

发表于由

His-Pro hydrochloride;

His-Pro hydrochloride 是一种由组氨酰和脯氨酸组成的二肽。

His-Pro hydrochlorideamp;;

His-Pro hydrochloride Chemical Structure

规格 价格 是否有货
10 mg ￥950 询问价格 货期

* Please select Quantity before adding items.

生物活性

His-Pro hydrochloride is a dipeptide consisting of histidyl and proline.

分子量

288.73

Formula

C11H17ClN4O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Park SW, et al. Alterations in pancreatic protein expression in STZ-induced diabetic rats and genetically diabetic mice in response to treatment with hypoglycemic dipeptide Cyclo (His-Pro). Cell Physiol Biochem. 2012;29(3-4):603-16.