MARCKS Peptide(151-175), Phosphorylated

MARCKS Peptide(151-175), Phosphorylated;

MARCKS Peptide(151-175), Phosphorylated 是一种由豆蔻酰化富丙氨酸 C 激酶底物蛋白 (MARCKS) 基本效应域片段组成的磷酸化多肽,MARCKS Peptide (151-175) 的磷酸化逆转了它对磷脂酶 C (PLC) 催化磷脂酰肌醇 -4,5- 二磷酸 (PIP2) 水解的抑制作用。

MARCKS Peptide(151-175), Phosphorylatedamp;;

MARCKS Peptide(151-175), Phosphorylated Chemical Structure

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生物活性

MARCKS Peptide(151-175), Phosphorylated is a phosphorylated peptide corresponding to the basic effector domain of myristoylated alanine-rich protein kinase C substrate protein (MARCKS). Phosphorylation of MARCKS Peptide (151-175) reverses its inhibition of phospholipase C (PLC)-catalyzed hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2)[1].

分子量

3320.80

Formula

C147H246N41O40P3

Sequence

Lys-Lys-Lys-Lys-Lys-Arg-Phe-{pSer}-Phe-Lys-Lys-{pSer}-Phe-Lys-Leu-Ser-Gly-Phe-{pSer}-Phe-Lys-Lys-Asn-Lys-Lys

Sequence Shortening

KKKKKRF-{pSer}-FKK-{pSer}-FKLSGF-{pSer}-FKKNKK

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Glaser M, et al. Myristoylated alanine-rich C kinase substrate (MARCKS) produces reversible inhibition of phospholipase C by sequestering phosphatidylinositol 4,5-bisphosphate in lateral domains..J Biol Chem. 1996 Oct 18;271(42):26187-93.

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