Fmoc-Phe-Ser(psi(Me,Me)pro)-OH

Fmoc-Phe-Ser(psi(Me,Me)pro)-OH;

Fmoc-Phe-Ser(psi(Me,Me)pro)-OH 是一种二肽。

Fmoc-Phe-Ser(psi(Me,Me)pro)-OHamp;;

Fmoc-Phe-Ser(psi(Me,Me)pro)-OH Chemical Structure

CAS No. : 878797-01-4

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg) ; Apply now ;
100 mg ¥500 In-stock
500 mg ¥1200 In-stock
1 g ; 询价 ;
5 g ; 询价 ;

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Fmoc-Phe-Ser(psi(Me,Me)pro)-OH 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Fmoc-Phe-Ser(psi(Me,Me)pro)-OH is a dipeptide.

分子量

514.57

Formula

C30H30N2O6

CAS 号

878797-01-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Protect from light

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)

溶解性数据
In Vitro:;

DMSO : 250 mg/mL (485.84 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.9434 mL 9.7169 mL 19.4337 mL
5 mM 0.3887 mL 1.9434 mL 3.8867 mL
10 mM 0.1943 mL 0.9717 mL 1.9434 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂:;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.08 mg/mL (4.04 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (4.04 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂:;10% DMSO ;; 90% corn oil

    Solubility: ≥ 2.08 mg/mL (4.04 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (4.04 mM,饱和度未知) 的澄清溶液,此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例,取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中,混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。

H-D-Phe-Pip-Arg-pNA(Synonyms: S-2238)

H-D-Phe-Pip-Arg-pNA;(Synonyms: S-2238)

H-D-Phe-Pip-Arg-pNA (S-2238) 是一种显色底物,在凝血酶的天然底物纤维蛋白原 α 链的 N 端部分之后形成。H-D-Phe-Pip-Arg-pNA 对凝血酶有特异性,用于测定抗凝血酶肝素辅因子 (AT-III)。使用 H-D-Phe-Pip-Arg-pNA 进行的 AT-III 分析灵敏、准确、易于执行。

H-D-Phe-Pip-Arg-pNAamp;;(Synonyms: S-2238)

H-D-Phe-Pip-Arg-pNA Chemical Structure

CAS No. : 64815-81-2

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H-D-Phe-Pip-Arg-pNA 的其他形式现货产品:

H-D-Phe-Pip-Arg-pNA acetate

生物活性

H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform[1][2].

分子量

552.63

Formula

C27H36N8O5

CAS 号

64815-81-2

Sequence Shortening

{D-Phe}-{Pip}-R-pNA

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Goodnight SH Jr, et al. Measurement of antithrombin III in normal and pathologic states using chromogenic substrate S-2238. Comparison with immunoelectrophoretic and factor Xa inhibition assays. Am J Clin Pathol. 1980;73(5):639-647.

    [2]. Voorthuizen H, Kluft C. Improved assay conditions for automated antithrombin III determinations with the chromogenic substrate S-2238. Thromb Haemost. 1984;52(3):350-353.

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA(Synonyms: For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA)

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA;(Synonyms: For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA)

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) 是一种甲酰肽受体 (FPR) 激动剂。

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFAamp;;(Synonyms: For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA)

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA Chemical Structure

规格 是否有货
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250 mg ; 询价 ;
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N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA 的其他形式现货产品:

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys

生物活性

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) is a formyl peptide receptor (FPR) agonist[1].

IC50 Target

Formyl peptide receptor[1]

分子量

938.04

Formula

C45H66F3N7O11

Sequence

N-Formyl-{NLE}-Leu-Phe-{NLE}-Tyr-Lys

Sequence Shortening

N-Formyl-{NLE}-LF-{NLE}-YK

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Stenfeldt AL, et al. The non-steroidal anti-inflammatory drug piroxicam blocks ligand binding to the formyl peptidereceptor but not the formyl peptide receptor like 1. Biochem Pharmacol. 2007 Oct 1;74(7):1050-6.

{Boc}-Phe-Leu-Phe-Leu-Phe TFA

{Boc}-Phe-Leu-Phe-Leu-Phe TFA;

{Boc}-Phe-Leu-Phe-Leu-Phe TFA 是一种甲酰肽受体 (FPR) 家族拮抗剂,可优先抑制通过甲酰肽受体触发的活性。

{Boc}-Phe-Leu-Phe-Leu-Phe TFAamp;;

{Boc}-Phe-Leu-Phe-Leu-Phe TFA Chemical Structure

规格 是否有货
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生物活性

{Boc}-Phe-Leu-Phe-Leu-Phe TFA is a formyl peptide receptor (FPR) family antagonist that preferentially inhibits activity triggered through the formyl peptide receptor[1].

分子量

899.99

Formula

C46H60F3N5O10

Sequence Shortening

{Boc}-FLFLF

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Anna-Lena Stenfeldt, et al. Cyclosporin H, Boc-MLF and Boc-FLFLF are antagonists that preferentially inhibit activity triggered through the formyl peptide receptor. Inflammation. 2007 Dec;30(6):224-9.

[D-p-Cl-Phe6,Leu17]-VIP

[D-p-Cl-Phe6,Leu17]-VIP;

[D-p-Cl-Phe6,Leu17]-VIP 是一种竞争性和选择性的血管活性肠肽 (VIP) 受体拮抗剂,IC50 值为 125.8 nM。[D-p-Cl-Phe6,Leu17]-VIP 对胰高血糖素,促胰液素和 GRF 受体无活性。

[D-p-Cl-Phe6,Leu17]-VIPamp;;

[D-p-Cl-Phe6,Leu17]-VIP Chemical Structure

CAS No. : 102805-45-8

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250 mg ; 询价 ;
500 mg ; 询价 ;

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[D-p-Cl-Phe6,Leu17]-VIP 的其他形式现货产品:

[D-p-Cl-Phe6,Leu17]-VIP TFA

生物活性

[D-p-Cl-Phe6,Leu17]-VIP is a competitive and selective antagonist of vasoactive intestinal peptide (VIP) receptor, with the IC50 of 125.8 nM. [D-p-Cl-Phe6,Leu17]-VIP has no activity on glucagon, secretin or GRF receptors[1][2][3].

IC50 Target

IC50: 125.8 nM (VIP receptor)[1]

分子量

3342.20

Formula

C148H239ClN44O42

CAS 号

102805-45-8

Sequence

His-Ser-Asp-Ala-Val-{Cl-Phe}-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Leu-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2

Sequence Shortening

HSDAV-{Cl-Phe}-TDNYTRLRKQLAVKKYLNSILN-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. Pozo D, et, al. Characterization of VIP receptor-effector system antagonists in rat and mouse peritoneal macrophages. Eur J Pharmacol. 1997 Mar 5; 321(3): 379-86.

    [2]. Pandol SJ, et, al. Vasoactive intestinal peptide receptor antagonist [4Cl-D-Phe6, Leu17] VIP. Am J Physiol. 1986 Apr; 250 (4 Pt 1): G553-7.

    [3]. Messmer B, et, al. Regulation of exocrine pancreatic secretion by cerebral TRH and CGRP: role of VIP, muscarinic, and adrenergic pathways. Am J Physiol. 1993 Feb; 264(2 Pt 1): G237-42.

Fmoc-Phe-Thr(psi(Me,Me)pro)-OH

Fmoc-Phe-Thr(psi(Me,Me)pro)-OH;

Fmoc-Phe-Thr(psi(Me,Me)pro)-OH 是一种二肽。

Fmoc-Phe-Thr(psi(Me,Me)pro)-OHamp;;

Fmoc-Phe-Thr(psi(Me,Me)pro)-OH Chemical Structure

CAS No. : 1196703-48-6

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Fmoc-Phe-Thr(psi(Me,Me)pro)-OH is a dipeptide.

分子量

528.60

Formula

C31H32N2O6

CAS 号

1196703-48-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

{Boc}-Phe-Leu-Phe-Leu-Phe

{Boc}-Phe-Leu-Phe-Leu-Phe;

{Boc}-Phe-Leu-Phe-Leu-Phe ({Boc}-FLFLF) 是一种甲酰肽受体 (FPR) 家族拮抗剂,可优先抑制通过甲酰肽受体触发的活性。

{Boc}-Phe-Leu-Phe-Leu-Pheamp;;

{Boc}-Phe-Leu-Phe-Leu-Phe Chemical Structure

CAS No. : 66556-73-8

规格 价格 是否有货
1 mg ¥2500 询问价格 货期
5 mg ¥6000 询问价格 货期
10 mg ¥10000 询问价格 货期

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生物活性

{Boc}-Phe-Leu-Phe-Leu-Phe ({Boc}-FLFLF) is a formyl peptide receptor (FPR) family antagonist that preferentially inhibits activity triggered through the formyl peptide receptor[1].

分子量

785.97

Formula

C44H59N5O8

CAS 号

66556-73-8

Sequence Shortening

{Boc}-FLFLF

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. Anna-Lena Stenfeldt, et al. Cyclosporin H, Boc-MLF and Boc-FLFLF are antagonists that preferentially inhibit activity triggered through the formyl peptide receptor. Inflammation. 2007 Dec;30(6):224-9.

Phe-Met-Arg-Phe Like Peptide, Snail Helix aspersa

Phe-Met-Arg-Phe Like Peptide, Snail Helix aspersa;

Phe-Met-Arg-Phe Like Peptide, Snail Helix aspersa 是一种来源 snail Helix aspersa 内脏和躯干肌肉的 FMRF 样肽。FMRF 是由 4 个氨基残基构成的神经肽。

Phe-Met-Arg-Phe Like Peptide, Snail Helix aspersaamp;;

Phe-Met-Arg-Phe Like Peptide, Snail Helix aspersa Chemical Structure

CAS No. : 98495-35-3

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

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生物活性

Phe-Met-Arg-Phe Like Peptide, Snail Helix aspersa is a FMRF-like peptide from visceral and somatic muscles of the snail Helix aspersa. FMRF (Phe-Met-Arg-Phe) is a neuropeptide peptide consisting of 4 amino acid residues[1].

分子量

904.02

Formula

C44H61N11O10

CAS 号

98495-35-3

Sequence

{pGLU}-Asp-Pro-Phe-Leu-Arg-Phe

Sequence Shortening

{pGLU}-DPFLRF

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. Lehman HK, et al. The actions of FMRFamide-like peptides on visceral and somatic muscles of the snail Helix aspersa. J Exp Biol. 1987 Sep;131:55-68.

Pro-Phe-Phe

Pro-Phe-Phe;

Pro-Phe-Phe 是最容易聚集的天然氨基酸三肽。Pro-Phe-Phe 形成独特的螺旋状薄片,通过芳香族干界面相配合。Pro-Phe-Phe 可用于模块化超螺旋自组装纳米结构的设计。

Pro-Phe-Pheamp;;

Pro-Phe-Phe Chemical Structure

CAS No. : 164257-32-3

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Pro-Phe-Phe is the most aggregation-prone tripeptide of natural amino acids. Pro-Phe-Phe forms unique helical-like sheets that mate via aromatic dry interfaces. Pro-Phe-Phe can be used for the design of modular super-helical self-assembling nanostructures[1][2].

分子量

409.48

Formula

C23H27N3O4

CAS 号

164257-32-3

Sequence

Pro-Phe-Phe

Sequence Shortening

PFF

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. Bera S, et, al. Rigid helical-like assemblies from a self-aggregating tripeptide. Nat Mater. 2019 May;18(5):503-509.

    [2]. Bera S, et, al. Rigid helical-like assemblies from a self-aggregating tripeptide. Nat Mater. 2019 May;18(5):503-509.

Gly-Phe-Arg

Gly-Phe-Arg;

Gly-Phe-Arg 是一种活性非常高的合成三肽,能够模仿青蟹的信息素。

Gly-Phe-Argamp;;

Gly-Phe-Arg Chemical Structure

CAS No. : 121822-47-7

规格 价格 是否有货
1 mg ¥1100 询问价格 货期
5 mg ¥3300 询问价格 货期
10 mg ¥5500 询问价格 货期

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生物活性

Gly-Phe-Arg is a superpotent synthetic tripeptide mimics of the mud-crab pumping pheromone.

体内研究
(In Vivo)

Gly-Phe-Arg produces not only a statistically significant increase in the relative number of pumping mud crabs but also a substantial increase in the pumping rate ratio[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

378.43

Formula

C17H26N6O4

CAS 号

121822-47-7

Sequence

Gly-Phe-Arg

Sequence Shortening

GFR

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. Pettis RJ, et al. Superpotent synthetic tripeptide mimics of the mud-crab pumping pheromone. Int J Pept Protein Res. 1993 Oct;42(4):312-9.