Fmoc-Phe-Ser(psi(Me,Me)pro)-OH

Fmoc-Phe-Ser(psi(Me,Me)pro)-OH;

Fmoc-Phe-Ser(psi(Me,Me)pro)-OH 是一种二肽。

Fmoc-Phe-Ser(psi(Me,Me)pro)-OHamp;;

Fmoc-Phe-Ser(psi(Me,Me)pro)-OH Chemical Structure

CAS No. : 878797-01-4

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg) ; Apply now ;
100 mg ¥500 In-stock
500 mg ¥1200 In-stock
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5 g ; 询价 ;

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Fmoc-Phe-Ser(psi(Me,Me)pro)-OH 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Fmoc-Phe-Ser(psi(Me,Me)pro)-OH is a dipeptide.

分子量

514.57

Formula

C30H30N2O6

CAS 号

878797-01-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Protect from light

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)

溶解性数据
In Vitro:;

DMSO : 250 mg/mL (485.84 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.9434 mL 9.7169 mL 19.4337 mL
5 mM 0.3887 mL 1.9434 mL 3.8867 mL
10 mM 0.1943 mL 0.9717 mL 1.9434 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂:;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.08 mg/mL (4.04 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (4.04 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂:;10% DMSO ;; 90% corn oil

    Solubility: ≥ 2.08 mg/mL (4.04 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (4.04 mM,饱和度未知) 的澄清溶液,此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例,取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中,混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。

H3K4(Me3) (1-20)

H3K4(Me3) (1-20);

H3K4(Me3) (1-20),一种组蛋白多肽,组蛋白 H3 对赖氨酸 4 (H3K4 me3) 的三甲基化在活性的常染色质中发现。

H3K4(Me3) (1-20)amp;;

H3K4(Me3) (1-20) Chemical Structure

规格 是否有货
1 mg 询价
5 mg 询价

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生物活性

H3K4(Me3) (1-20) is a histone peptide. Trimethylation of histone H3 on lysine 4 (H3K4 me3) is found in active euchromatin but not in silent heterochromatin[1][2].

分子量

2226.64

Formula

C94H174N35O27

Sequence

Ala-Arg-Thr-{Lys(Me3)}-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu

Sequence Shortening

ART-{Lys(Me3)}-QTARKSTGGKAPRKQL

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Mulder KW, et al. Regulation of histone H3K4 tri-methylation and PAF complex recruitment by the Ccr4-Not complex. Nucleic Acids Res. 2007;35(7):2428-2439.

    [2]. Fujino T, et al. Alteration of histone H3K4 methylation in glomerular podocytes associated with proteinuria in patients with membranous nephropathy. BMC Nephrol. 2016;17(1):179. Published 2016 Nov 17.

Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH

Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH;

Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH是个二肽。

Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OHamp;;

Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH Chemical Structure

CAS No. : 957780-56-2

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide.

分子量

566.64

Formula

C31H38N2O8

CAS 号

957780-56-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OH

Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OH;

Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OH 是一种二肽。

Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OHamp;;

Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OH Chemical Structure

CAS No. : 920519-32-0

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide.

分子量

552.62

Formula

C30H36N2O8

CAS 号

920519-32-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

Fmoc-Asp(OtBu)-Ser(psi(Me,Me)pro)-OH

Fmoc-Asp(OtBu)-Ser(psi(Me,Me)pro)-OH;

Fmoc-Asp(OtBu)-Ser(psi(Me,Me)pro)-OH 是一种二肽。

Fmoc-Asp(OtBu)-Ser(psi(Me,Me)pro)-OHamp;;

Fmoc-Asp(OtBu)-Ser(psi(Me,Me)pro)-OH Chemical Structure

CAS No. : 955048-92-7

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Fmoc-Asp(OtBu)-Ser(psi(Me,Me)pro)-OH is a dipeptide.

分子量

538.59

Formula

C29H34N2O8

CAS 号

955048-92-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Fmoc-Val-Thr(psi(Me,Me)pro)-OH

Fmoc-Val-Thr(psi(Me,Me)pro)-OH;

Fmoc-Val-Thr(psi(Me,Me)pro)-OH 是一种二肽。

Fmoc-Val-Thr(psi(Me,Me)pro)-OHamp;;

Fmoc-Val-Thr(psi(Me,Me)pro)-OH Chemical Structure

CAS No. : 168216-05-5

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Fmoc-Val-Thr(psi(Me,Me)pro)-OH is a dipeptide.

分子量

480.55

Formula

C27H32N2O6

CAS 号

168216-05-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

Fmoc-Tyr(tBu)-Thr(psi(Me,Me)pro)-OH

Fmoc-Tyr(tBu)-Thr(psi(Me,Me)pro)-OH;

Fmoc-Tyr(tBu)-Thr(psi(Me,Me)pro)-OH 是一种二肽。

Fmoc-Tyr(tBu)-Thr(psi(Me,Me)pro)-OHamp;;

Fmoc-Tyr(tBu)-Thr(psi(Me,Me)pro)-OH Chemical Structure

CAS No. : 920519-31-9

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Fmoc-Tyr(tBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide.

分子量

600.70

Formula

C35H40N2O7

CAS 号

920519-31-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

Fmoc-Gly-Ser(psi(Me,Me)pro)-OH

Fmoc-Gly-Ser(psi(Me,Me)pro)-OH;

Fmoc-Gly-Ser(psi(Me,Me)pro)-OH 是一种二肽。

Fmoc-Gly-Ser(psi(Me,Me)pro)-OHamp;;

Fmoc-Gly-Ser(psi(Me,Me)pro)-OH Chemical Structure

CAS No. : 1095952-22-9

规格 价格 是否有货 数量
500 mg ¥350 In-stock
1 g ; 询价 ;
5 g ; 询价 ;

* Please select Quantity before adding items.

Fmoc-Gly-Ser(psi(Me,Me)pro)-OH 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Fmoc-Gly-Ser(psi(Me,Me)pro)-OH is a dipeptide.

分子量

424.45

Formula

C23H24N2O6

CAS 号

1095952-22-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -80deg;C 2 years
-20deg;C 1 year
In solvent -80deg;C 6 months
-20deg;C 1 month
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

Fmoc-Ser(tBu)-Ser(psi(Me,Me)pro)-OH

Fmoc-Ser(tBu)-Ser(psi(Me,Me)pro)-OH;

Fmoc-Ser(tBu)-Ser(psi(Me,Me)pro)-OH 是一种二肽。

Fmoc-Ser(tBu)-Ser(psi(Me,Me)pro)-OHamp;;

Fmoc-Ser(tBu)-Ser(psi(Me,Me)pro)-OH Chemical Structure

CAS No. : 1000164-43-1

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Fmoc-Ser(tBu)-Ser(psi(Me,Me)pro)-OH is a dipeptide.

分子量

510.58

Formula

C28H34N2O7

CAS 号

1000164-43-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

H3K4(Me2) (1-20)

H3K4(Me2) (1-20);

H3K4(Me2) (1-20) 是一种组蛋白多肽。H3K4me2 调节DNA损伤后蛋白质生物合成和稳态的恢复。

H3K4(Me2) (1-20)amp;;

H3K4(Me2) (1-20) Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

H3K4(Me2) (1-20) is a histone peptide. H3K4me2 regulates the recovery of protein biosynthesis and homeostasis following DNA damage[1][2].

分子量

2211.61

Formula

C93H171N35O27

Sequence

Ala-Arg-Thr-{Lys(Me2)}-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu

Sequence Shortening

ART-{Lys(Me2)}-QTARKSTGGKAPRKQL

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Mulder KW, et al. Regulation of histone H3K4 tri-methylation and PAF complex recruitment by the Ccr4-Not complex. Nucleic Acids Res. 2007;35(7):2428-2439.

    [2]. Wang S, et al. H3K4me2 regulates the recovery of protein biosynthesis and homeostasis following DNA damage. Nat Struct Mol Biol. 2020;27(12):1165-1177.