标签归档：glu

Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH

发表于由

Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH;

Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH是个二肽。

Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OHamp;;

Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH Chemical Structure

CAS No. : 957780-56-2

规格 是否有货
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250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide.

分子量

566.64

Formula

C31H38N2O8
CAS 号

957780-56-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

Ala-Glu-OH

发表于由

Ala-Glu-OH; 纯度: ge;98.0%

Ala-Glu-OH 是一种二肽试剂。

Ala-Glu-OHamp;;

Ala-Glu-OH Chemical Structure

CAS No. : 13187-90-1

规格 价格 是否有货 数量
10 mg ￥500 In-stock
25 mg ￥900 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

* Please select Quantity before adding items.

Ala-Glu-OH 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Ala-Glu-OH is an agent of the dipeptide[1][2].

分子量

218.21

Formula

C8H14N2O5
CAS 号

13187-90-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro:;

H2O : 250 mg/mL (1145.69 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.5827 mL 22.9137 mL 45.8274 mL
5 mM 0.9165 mL 4.5827 mL 9.1655 mL
10 mM 0.4583 mL 2.2914 mL 4.5827 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Smid EJ, et al. Mechanism and energetics of dipeptide transport in membrane vesicles of Lactococcus lactis. J Bacteriol. 1989;171(1):292-298.

    [2]. Kim SJ, et al. Replacement of glutamine with the dipeptide derivative alanyl-glutamine enhances in vitro maturation of porcine oocytes and development of embryos. Zygote. 2014;22(2):286-289.

Ac-Ile-Glu-Thr-Asp-pNA

发表于由

Ac-Ile-Glu-Thr-Asp-pNA;

Ac-Ile-Glu-Thr-Asp-pNA 是 caspase-8 的底物。Caspase-8 结合并裂解Ile-Glu-Thr-Asp (IETD) 肽序列，释放对硝基苯胺，可通过 405 nm 处的比色检测来定量检测酶活性。

Ac-Ile-Glu-Thr-Asp-pNAamp;;

Ac-Ile-Glu-Thr-Asp-pNA Chemical Structure

CAS No. : 219138-21-3

规格 是否有货
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250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity[1].

分子量

638.62

Formula

C27H38N6O12
CAS 号

219138-21-3
Sequence Shortening

Ac-IETD-pNA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Smith GK, et al. Expression, preparation, and high-throughput screening of caspase-8: discovery of redox-based and steroid diacid inhibition. Arch Biochem Biophys. 2002;399(2):195-205.

Glu-Plasminogen Solution, from Human Plasma 品牌：FUJIFILM Wako

发表于由

Glu-Plasminogen Solution, from Human Plasma

品牌：FUJIFILM Wako
CAS No.：
储存条件：-80℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

165-24321

 for Cellbiology 1 mg –

Glu-Plasminogen Solution, from Human Plasma 品牌：FUJIFILM Wako

 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

[Glu4]-Oxytocin

发表于由

[Glu4]-Oxytocin;

[Glu4]-Oxytocin 是一种催产素衍生物，可通过多种方法对水溶液中的 “类催产素” 分子的构象进行综合研究。

[Glu4]-Oxytocinamp;;

[Glu4]-Oxytocin Chemical Structure

CAS No. : 4314-67-4

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

[Glu4]-Oxytocin is an appropriate derivative of oxytocin for conducting a comprehensive investigation by a variety of methods of the conformation of “oxytocin-like” molecules in aqueous solution[1].

分子量

1008.17

Formula

C43H65N11O13S2
CAS 号

4314-67-4
Sequence Shortening

CYIENCPLG-NH2 (Disulfide bridge:Cys1-Cys6)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Walter R, et al. H N.M.R. study of the conformation of [Glu4] oxytocin and its lanthanide complexes in aqueous solution. Int J Pept Protein Res. 1981;17(1):56-64.

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH

发表于由

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH;

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH (compound 1) 是一种高亲和力的五肽，与 src SH2 域结合 (IC50≈1 µM)。Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH 是 src SH3-SH2：磷酸蛋白相互作用的抑制剂。

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OHamp;;

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH Chemical Structure

CAS No. : 159439-02-8

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC50≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH is an inhibitor for src SH3-SH2:phosphoprotein interactions[1].

分子量

803.70

Formula

C32H46N5O17P
CAS 号

159439-02-8
Sequence Shortening

Ac–{Tyr(PO3H2)}-EEIE-OH
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. G J Pacofsky, et al. Potent dipeptide inhibitors of the pp60c-src SH2 domain. J Med Chem. 1998 May 21;41(11):1894-908.

H-Glu(Met-OH)-OH

发表于由

H-Glu(Met-OH)-OH;

H-Glu(Met-OH)-OH 可引起羟基自由基的氧化。

H-Glu(Met-OH)-OHamp;;

H-Glu(Met-OH)-OH Chemical Structure

CAS No. : 17663-87-5

规格 是否有货
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250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

H-Glu(Met-OH)-OH could induce oxidation of hydroxyl radical[1].

分子量

278.33

Formula

C10H18N2O5S
CAS 号

17663-87-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Krzysztof Bobrowski, et al.˙OH radical induced decarboxylation of γ-glutamylmethionine and S-alkylglutathione derivatives: evidence for two different pathways involving C- and N-terminal decarboxylation. Journal of the Chemical Society, Perkin Transactions 2.

Fmoc-Glu(OtBu)-Ser(psi(Me,Me)pro)-OH

发表于由

Fmoc-Glu(OtBu)-Ser(psi(Me,Me)pro)-OH;

Fmoc-Glu(OtBu)-Ser(psi(Me,Me)pro)-OH 是一种二肽。

Fmoc-Glu(OtBu)-Ser(psi(Me,Me)pro)-OHamp;;

Fmoc-Glu(OtBu)-Ser(psi(Me,Me)pro)-OH Chemical Structure

CAS No. : 909115-33-9

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Fmoc-Glu(OtBu)-Ser(psi(Me,Me)pro)-OH is a dipeptide.

分子量

552.62

Formula

C30H36N2O8
CAS 号

909115-33-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Ermelinda Vernieri, et al. An optimized Fmoc synthesis of human defensin 5. Amino Acids. 2014 Feb;46(2):395-400.

[Glu1]-Fibrinopeptide B(Synonyms: [Glu1]-纤维蛋白肽B)

发表于由

[Glu1]-Fibrinopeptide B;(Synonyms: [Glu1]-纤维蛋白肽B)

[Glu1]-Fibrinopeptide B 衍生自纤维蛋白肽B氨基酸残基1-14。人纤维蛋白肽B（hFpB）是来自纤维蛋白原B β链的凝血酶衍生的蛋白水解裂解产物，可用于刺激中性粒细胞 (PMN)，单核细胞和成纤维细胞。

[Glu1]-Fibrinopeptide Bamp;;(Synonyms: [Glu1]-纤维蛋白肽B)

[Glu1]-Fibrinopeptide B Chemical Structure

CAS No. : 103213-49-6

规格 价格 是否有货
500 μg ￥1200 询问价格 货期
1 mg ￥1800 询问价格 货期
5 mg ￥7200 询问价格 货期

* Please select Quantity before adding items.

生物活性

[Glu1]-Fibrinopeptide B is derived from fibrinopeptide B amino acid residues 1-14. Human fibrinopeptide B (hFpB), a thrombin-derived proteolytic cleavage product of the fibrinogen B beta-chain, to stimulate neutrophils (PMN), monocytes, and fibroblasts.

体外研究
(In Vitro)

hFpB causes directed cell migration of PMN and fibroblasts that is optimal at approximately 10 nM. hFpB causes a rapid, dose-dependent increase in PMN cytoskeletal associated actin, but unlike fMLP, hFpB does not cause PMN aggregation, release of lysosomal enzymes (lysozyme and beta-glucuronidase), or the production of superoxide anion. These results suggest that hFpB may have a role in recruiting PMN and fibroblasts at sites of fibrin deposition and turnover. The capacity of hFpB to cause PMN chemotaxis without causing concurrent release of lysosomal enzymes or the production of superoxide anion is further evidence for the complexity of PMN responses to chemotactic agents[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1570.60

Formula

C66H95N19O26
CAS 号

103213-49-6
Sequence

Glu-Gly-Val-Asn-Asp-Asn-Glu-Glu-Gly-Phe-Phe-Ser-Ala-Arg
Sequence Shortening

EGVNDNEEGFFSAR
中文名称

[Glu1]-纤维蛋白肽B
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Senior RM, et al. Effects of fibrinogen derivatives upon the inflammatory response. Studies with human fibrinopeptide B. J Clin Invest. 1986 Mar;77(3):1014-9.

γ-Glu-Phe(Synonyms: γ-Glutamylphenylalanine)

发表于由

γ-Glu-Phe;(Synonyms: γ-Glutamylphenylalanine) 纯度: 99.85%

γ-Glu-Phe (γ-Glutamylphenylalanine) 是由解淀粉芽孢杆菌 (GBA) 和米曲霉 (GAO) 合成的。γ-Glu-Phe 或酶后反应混合物可增强商业酱油和模型鸡汤的鲜味强度。

γ-Glu-Pheamp;;(Synonyms: γ-Glutamylphenylalanine)

γ-Glu-Phe Chemical Structure

CAS No. : 7432-24-8

规格 价格 是否有货 数量
5 mg ￥700 In-stock
10 mg ￥1100 In-stock
50 mg ￥2400 In-stock
100 mg ￥3500 In-stock
200 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

gamma;-Glu-Phe 相关产品

bull;相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Metabolism/Protease Compound Library
  • Natural Product Library
  • Human Endogenous Metabolite Compound Library
  • Peptidomimetic Library
  • Microbial Metabolite Library
  • Food-Sourced Compound Library
  • Peptide Library

生物活性

γ-Glu-Phe (γ-Glutamylphenylalanine) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth[1].

IC50 Target

Human Endogenous Metabolite

;

体外研究
(In Vitro)

γ-Glu-Phe, γ-Glu-Met and γ-Glu-Val, are identified in sourdough by liquid chromatography-tandem mass spectrometry in MRM mode. γ-Glutamyl dipeptides are found in higher concentrations in sourdough fermented with L. reuteri when compared to the chemically acidified controls. Proteolysis is an important factor for generation of γ-glutamyl dipeptides. Sensory evaluation of bread reveals that sourdough bread with higher concentrations of γ-glutamyl dipeptides ranks higher with respect to the taste intensity when compared to regular bread and type I sourdough bread. Sourdough breads fermented with L. reuteri LTH5448 and L. reuteri 100-23 differ with respect to the intensity of the salty taste; this difference corresponds to a different concentration of γ-glutamyl dipeptides[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

294.30

Formula

C14H18N2O5
CAS 号

7432-24-8
Sequence

gamma;-Glu-Phe
Sequence Shortening

gamma;-EF
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -80deg;C 2 years
-20deg;C 1 year
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

H2O : ≥ 50 mg/mL (169.89 mM)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.3979 mL 16.9895 mL 33.9789 mL
5 mM 0.6796 mL 3.3979 mL 6.7958 mL
10 mM 0.3398 mL 1.6989 mL 3.3979 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Yang J, et al. Synthesis and Sensory Characteristics of Kokumi γ-[Glu]n-Phe in the Presence of Glutamine and Phenylalanine: Glutaminase from Bacillus amyloliquefaciens or Aspergillus oryzae as the Catalyst. J Agric Food Chem. 2017 Oct 4;65(39):8696-8703.

    [2]. Zhao CJ, et al. Synthesis of Taste-Active γ-Glutamyl Dipeptides during Sourdough Fermentation by Lactobacillus reuteri. J Agric Food Chem. 2016 Oct 12;64(40):7561-7568.