标签归档：ala

Ala-Glu-OH

发表于由

Ala-Glu-OH; 纯度: ge;98.0%

Ala-Glu-OH 是一种二肽试剂。

Ala-Glu-OHamp;;

Ala-Glu-OH Chemical Structure

CAS No. : 13187-90-1

规格 价格 是否有货 数量
10 mg ￥500 In-stock
25 mg ￥900 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

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Ala-Glu-OH 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Ala-Glu-OH is an agent of the dipeptide[1][2].

分子量

218.21

Formula

C8H14N2O5
CAS 号

13187-90-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro:;

H2O : 250 mg/mL (1145.69 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.5827 mL 22.9137 mL 45.8274 mL
5 mM 0.9165 mL 4.5827 mL 9.1655 mL
10 mM 0.4583 mL 2.2914 mL 4.5827 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Smid EJ, et al. Mechanism and energetics of dipeptide transport in membrane vesicles of Lactococcus lactis. J Bacteriol. 1989;171(1):292-298.

    [2]. Kim SJ, et al. Replacement of glutamine with the dipeptide derivative alanyl-glutamine enhances in vitro maturation of porcine oocytes and development of embryos. Zygote. 2014;22(2):286-289.

N-Formyl-Met-Ala-Ser

发表于由

N-Formyl-Met-Ala-Ser;

N-Formyl-Met-Ala-Ser 是一个多肽，在中性粒细胞中，与甲酰肽受体 (formyl peptide receptors) 结合。

N-Formyl-Met-Ala-Seramp;;

N-Formyl-Met-Ala-Ser Chemical Structure

CAS No. : 17351-32-5

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生物活性

N-Formyl-Met-Ala-Ser is a peptide, binds to formyl peptide receptors on neutrophils.

分子量

335.38

Formula

C12H21N3O6S
CAS 号

17351-32-5
Sequence

Foemyl-Met-Ala-Ser
Sequence Shortening

Formyl-MAS
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

[Ala11,D-Leu15]-Orexin B(human)

发表于由

[Ala11,D-Leu15]-Orexin B(human);

[Ala11,D-Leu15]-Orexin B(human) 是一种有效的，选择性的 orexin-2 receptor (OX2) 的激动剂。[Ala11,D-Leu15]-Orexin B(human) 对 OX2 (EC50=0.13 nM) 比对 OX1 (52 nM) 高出 400 倍的选择性。

[Ala11,D-Leu15]-Orexin B(human)amp;;

[Ala11,D-Leu15]-Orexin B(human) Chemical Structure

CAS No. : 532932-99-3

规格 是否有货
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生物活性

[Ala11,D-Leu15]-Orexin B(human) is a potent and selective orexin-2 receptor (OX2) agonist. [Ala11,D-Leu15]-Orexin B(human) shows a 400-fold selectivity for the OX2 (EC50=0.13 nM) over OX1 (52 nM)[1].

IC50 Target[1]

OX2

0.13 nM (EC50)

OX1

52 nM (EC50)

分子量

2857.26

Formula

C120H206N44O35S
CAS 号

532932-99-3
Sequence

Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Ala-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
Sequence Shortening

RSGPPGLQGRAQRLLQASGNHAAGILTM-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Asahi S, et al. Development of an orexin-2 receptor selective agonist, [Ala(11), D-Leu(15)]orexin-B. Bioorg Med Chem Lett. 2003;13(1):111-113.

[Ala113]MBP(104-118)

发表于由

[Ala113]MBP(104-118);

[Ala113]MBP(104-118) 是 protein kinase C (PKC) 的非竞争性的肽抑制剂，IC50 值范围为 28-62 μM。

[Ala113]MBP(104-118)amp;;

[Ala113]MBP(104-118) Chemical Structure

CAS No. : 99026-78-5

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

[Ala113]MBP(104-118) is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC50s ranging from 28-62 μM[1].

IC50 Target[1]

PKC

28-62 mu;M (IC50)

分子量

1493.67

Formula

C67H104N20O19
CAS 号

99026-78-5
Sequence Shortening

GKGRGLSLSAFSWGA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Su HD, et, al. Synthetic myelin basic protein peptide analogs are specific inhibitors of phospholipid/calcium-dependent protein kinase (protein kinase C). Biochem Biophys Res Commun. 1986 Jan 14; 134(1): 78-84.

[Ala107]MBP(104-118) TFA

发表于由

[Ala107]MBP(104-118) TFA;

[Ala107]MBP(104-118) TFA 是 protein kinase C (PKC) 的非竞争性的肽抑制剂，IC50 值范围为 46-145 μM。

[Ala107]MBP(104-118) TFAamp;;

[Ala107]MBP(104-118) TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

[Ala107]MBP(104-118) TFA is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC50s ranging from 46-145 μM[1].

IC50 Target[1]

PKC

46-145 mu;M (IC50)

分子量

1607.69

Formula

C69H105F3N20O21
Sequence Shortening

GKGAGLSLSRFSWGA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Su HD, et, al. Synthetic myelin basic protein peptide analogs are specific inhibitors of phospholipid/calcium-dependent protein kinase (protein kinase C). Biochem Biophys Res Commun. 1986 Jan 14; 134(1): 78-84.

[Ala107]MBP(104-118)

发表于由

[Ala107]MBP(104-118);

[Ala107]MBP(104-118) 是 protein kinase C (PKC) 的非竞争性的肽抑制剂，IC50 值范围为 46-145 μM。

[Ala107]MBP(104-118)amp;;

[Ala107]MBP(104-118) Chemical Structure

CAS No. : 99026-77-4

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

[Ala107]MBP(104-118) is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC50s ranging from 46-145 μM[1].

IC50 Target[1]

PKC

46-145 mu;M (IC50)

分子量

1493.67

Formula

C67H104N20O19
CAS 号

99026-77-4
Sequence Shortening

GKGAGLSLSRFSWGA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Su HD, et, al. Synthetic myelin basic protein peptide analogs are specific inhibitors of phospholipid/calcium-dependent protein kinase (protein kinase C). Biochem Biophys Res Commun. 1986 Jan 14; 134(1): 78-84.

H-Ala-Ala-Tyr-OH TFA

发表于由

H-Ala-Ala-Tyr-OH TFA;

H-Ala-Ala-Tyr-OH TFA 可用于合成突变型多肽。

H-Ala-Ala-Tyr-OH TFAamp;;

H-Ala-Ala-Tyr-OH TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

H-Ala-Ala-Tyr-OH TFA can be synthesized mutant peptides[1][2].

分子量

437.37

Formula

C17H22F3N3O7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. das Neves GM, et al. In Silico Design of New Inhibitors of Guanine Phosphoribosyltransferase (GPRT) from Giardia lamblia as Antiparasitic Drug Candidates. Curr Drug Discov Technol. 2017;14(1):8-24.

    [2]. B-cell antigenic multi-epitope peptide linked in tandem in OmpU of vibrio mimicus, making method and application thereof. CN101747416A.

[Ala113]MBP(104-118) TFA

发表于由

[Ala113]MBP(104-118) TFA;

[Ala113]MBP(104-118) TFA 是 protein kinase C (PKC) 的非竞争性的肽抑制剂，IC50 值范围为 28-62 μM。

[Ala113]MBP(104-118) TFAamp;;

[Ala113]MBP(104-118) TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

[Ala113]MBP(104-118) TFA is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC50s ranging from 28-62 μM[1].

IC50 Target[1]

PKC

28-62 mu;M (IC50)

分子量

1607.69

Formula

C69H105F3N20O21
Sequence Shortening

GKGRGLSLSAFSWGA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Su HD, et, al. Synthetic myelin basic protein peptide analogs are specific inhibitors of phospholipid/calcium-dependent protein kinase (protein kinase C). Biochem Biophys Res Commun. 1986 Jan 14; 134(1): 78-84.

H-Ala-Ala-Tyr-OH

发表于由

H-Ala-Ala-Tyr-OH;

H-Ala-Ala-Tyr-OH 用于合成突变型多肽。

H-Ala-Ala-Tyr-OHamp;;

H-Ala-Ala-Tyr-OH Chemical Structure

CAS No. : 67131-52-6

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

H-Ala-Ala-Tyr-OH can be synthesized mutant peptides[1][2].

分子量

323.34

Formula

C15H21N3O5
CAS 号

67131-52-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. das Neves GM, et al. In Silico Design of New Inhibitors of Guanine Phosphoribosyltransferase (GPRT) from Giardia lamblia as Antiparasitic Drug Candidates. Curr Drug Discov Technol. 2017;14(1):8-24.

    [2]. B-cell antigenic multi-epitope peptide linked in tandem in OmpU of vibrio mimicus, making method and application thereof. CN101747416A.

Fmoc-Ala-Thr(psi(Me,Me)pro)-OH

发表于由

Fmoc-Ala-Thr(psi(Me,Me)pro)-OH;

Fmoc-Ala-Thr(psi(Me,Me))-OH 是 Fmoc 保护的丙氨酸衍生物，可用于肽合成。

Fmoc-Ala-Thr(psi(Me,Me)pro)-OHamp;;

Fmoc-Ala-Thr(psi(Me,Me)pro)-OH Chemical Structure

CAS No. : 252554-79-3

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Fmoc-Ala-Thr(psi(Me,Me))-OH is an Fmoc protected alanine derivative and can be used for peptide synthesis.

分子量

452.50

Formula

C25H28N2O6
CAS 号

252554-79-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.