Oxford牛津X-MET5100(手持式XRF元素分析仪)

Oxford牛津X-MET5100(手持式XRF元素分析仪)

Oxford牛津X-MET5100(手持式XRF元素分析仪)

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Oxford牛津X-MET5100(手持式XRF元素分析仪)

X-MET5100 手持式 X 射线荧光光谱仪保证了铝及钛合金的实验室质量分析的精确性,它对检测铜、镍和钢等金属材料中含有的轻金属元素时的敏感性也是无与伦比的,无需借助复杂的真空泵或氦气罐等附属设备就可对镁、铝、硅等轻元素进行测量。硅漂移探测器 (SDD)、45 千伏 X 射线管和经验系数分析方法的强大结合,意味着 X-MET5100 可以在短短 1 秒钟内,准确地分析和确定金属合金成分。受限物质(重金属元素)、玩具中的铅、土壤中的污染物和矿石中的微量物质可以得到准确测量,其速度之快,在从前是绝无可能的。在几秒钟之内,就可以得到 ppm 级的痕量元素检测结果。

金属材料可靠性鉴定(PMI)

  • 废旧金属回收行业
  • 环境重金属监测(土壤和RoHS)
  • 航空和汽车工业
  • 矿石勘察、现场挖掘控制和矿山制图
  • X-MET5100 X射线荧光(XRF)光谱仪能够以无与伦比的速度和检测精度,提供高效可靠的实时检测结果。
    这种高效的便携式检测工具 – 对金属回收、塑料回收、电子制品及木材回收而言必不可少 – 率先实现在无需真空泵或氦气罐附属装置的条件下,即可对6061/6063合金进行分拣。
快速牌号鉴定,可以检测铝元素!
  • 1秒无损检测,完成合金分类和质量控制!
  • 可靠的铝、镁、硅分析,无需真空泵或氦气罐
  • 各种合金牌号的可靠鉴定
  • 检测下限低至ppm级
  • 坚固耐用;经IP54认证,防尘、放潮
  • 电池可提供长效的操作时间
快速废旧金属分拣!
  • 合金分类和牌号鉴定只需1秒!
  • 可靠的铝、镁、硅分析,无需真空泵或氦气罐
  • 快速的铬、镍、钼、铜分析,即使在低含量条件下
  • 可经受所有天气条件
  • 电池可提供长效的操作时间

Oxford牛津X-MET5000(手持式XRF元素分析仪)

Oxford牛津X-MET5000(手持式XRF元素分析仪)

Oxford牛津X-MET5000(手持式XRF元素分析仪)

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Oxford牛津X-MET5000(手持式XRF元素分析仪)

牛津仪器推出了新款手持式X射线荧光光谱仪, 可满足各种苛刻的元素分析要求。

牛津仪器宣布推出一款坚固的手持式X射线荧光光谱仪(XRF) — X-MET5000,该仪器能够进行高精度、高可靠性的元素分析。牛津仪器的手持式X射线荧光光谱仪誉满全球,X-MET5000是其第四代产品。

这款全新的光谱仪拥有高性能和高可靠性,它综合了牛津仪器的PentaFET专利探测器技术,能够保证所有用户感兴趣的元素均得到快速分析,并且提供更低的元素检测下限。 这款光谱仪专门为各种最严格的质量控制应用而设计,例如金属废料回收利用、合金分类鉴定以及玩具和消费产品的含铅量检测结果是否符合RoHS指令要求。此外,X-MET5000还能满足采矿业的需求,也可在环境监测行业中用于测定土壤中的重金属含量。

X-MET5000的主要优势就在于其轻元素处理 (LET) 模式,此模式可允许对重金属进行快速、准确的分析——即使样品中存在铝和硅等轻元素,仍不会影响其分析结果。而其他普通分析仪由于只使用“基本参数(FP)法”,根本无法分析由于轻元素的存在对最终的分析结果造成的干扰。

这款坚固、可靠的工具通过了IP54 (NEMA 3)认证,具备卓越的防水防尘性能。X-MET5000是恶劣应用环境的理想选择。该仪器所配备的电池可持续使用一个工作日,从而提高了工作效率。

其强大的用户自定义软件能够提供准确的分析结果,从而提高了“合格/不合格”决定的可靠性。X-MET5000能够识别材料类型,并自动选择最佳分析方法。

借助于其可选配的台式支架,可免除执行多分析任务时的手工操作,同时又不会令测量结果的置信水平受到任何影响。

Oxford牛津ARC-MET8000便携式直读光谱仪

Oxford牛津ARC-MET8000便携式直读光谱仪

Oxford牛津ARC-MET8000便携式直读光谱仪

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Oxford牛津ARC-MET8000便携式直读光谱仪

便携式直读光谱分析仪用于鉴定金属中所有的重要元素——尤其是那些需要高精确度的分析和痕量元素的分析,如C、Al、S、P、Mg、Si, 并可以分检低合金钢和铝合金。例如,可以分辨316 H (>0.04% C) 和 316 L (<0.03% C)。
 
整个生产周期只需使用1台仪器!
原料分类(回收金属)
半成品质量控制
成品质量控制
金属分类分析中,钢铁中碳元素的识别和分析是最受关注的。例如,在焊接工作中,ARC-MET8000有独特的能力,在空气和氩气模式中都可以测量碳含量。
 
ARC-MET8000 可提供:
使用空气和氩气来测出精确的结果
快速的牌号鉴定和分析
只有一个探头,却可以完整的显示结果
在几分钟里,利用空气的燃烧完成低级别的碳分析
使用电池操作,主机和探头用长线缆连接,可以方便移动
ARC-MET8000的独特性:探头是整个系统的“心脏”部件

N-Formyl-Met-Ala-Ser

N-Formyl-Met-Ala-Ser;

N-Formyl-Met-Ala-Ser 是一个多肽,在中性粒细胞中,与甲酰肽受体 (formyl peptide receptors) 结合。

N-Formyl-Met-Ala-Seramp;;

N-Formyl-Met-Ala-Ser Chemical Structure

CAS No. : 17351-32-5

规格 是否有货
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生物活性

N-Formyl-Met-Ala-Ser is a peptide, binds to formyl peptide receptors on neutrophils.

分子量

335.38

Formula

C12H21N3O6S

CAS 号

17351-32-5

Sequence

Foemyl-Met-Ala-Ser

Sequence Shortening

Formyl-MAS

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

H-Glu(Met-OH)-OH

H-Glu(Met-OH)-OH;

H-Glu(Met-OH)-OH 可引起羟基自由基的氧化。

H-Glu(Met-OH)-OHamp;;

H-Glu(Met-OH)-OH Chemical Structure

CAS No. : 17663-87-5

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生物活性

H-Glu(Met-OH)-OH could induce oxidation of hydroxyl radical[1].

分子量

278.33

Formula

C10H18N2O5S

CAS 号

17663-87-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Krzysztof Bobrowski, et al.˙OH radical induced decarboxylation of γ-glutamylmethionine and S-alkylglutathione derivatives: evidence for two different pathways involving C- and N-terminal decarboxylation. Journal of the Chemical Society, Perkin Transactions 2.

[Des-Tyr1]-Met-Enkephalin

[Des-Tyr1]-Met-Enkephalin;

[Des-Tyr1]-Met-Enkephalin 是一种四肽,是脑啡肽的降解产物。

[Des-Tyr1]-Met-Enkephalinamp;;

[Des-Tyr1]-Met-Enkephalin Chemical Structure

CAS No. : 61370-88-5

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生物活性

[Des-Tyr1]-Met-Enkephalin, a tetrapeptide, is a degradationproduct of enkephalins[1].

体外研究
(In Vitro)

Tetrapeptide H-gily-gly-phe-met-oh shows very littleactivity using the mouse[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

410.49

Formula

C18H26N4O5S

CAS 号

61370-88-5

Sequence Shortening

GGFM

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. J M Hambrook, et al. Mode of deactivation of the enkephalins by rat and human plasma and rat brain homogenates. Nature. 1976 Aug 26;262(5571):782-3.

N-Formyl-Met-Leu-Phe-Lys(Synonyms: fMLFK)

N-Formyl-Met-Leu-Phe-Lys;(Synonyms: fMLFK)

N-Formyl-Met-Leu-Phe-Lys 是一种多肽,为有效、选择性的 FPR1 激动剂,对 FPR1,FPR2 和 FPR2-D2817.32G 的 EC50 值分别为 3.5 nM,6.7 μM 和 0.88 μM。

N-Formyl-Met-Leu-Phe-Lysamp;;(Synonyms: fMLFK)

N-Formyl-Met-Leu-Phe-Lys Chemical Structure

CAS No. : 67247-11-4

规格 是否有货
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生物活性

N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively[1].

IC50 Target

EC50: 3.5 nM (FPR1), 6.7 μM (FPR2), 0.88 μM (FPR2-D2817.32G)[1]

分子量

565.73

Formula

C27H43N5O6S

CAS 号

67247-11-4

Sequence

Formyl-Met-Leu-Phe-Lys

Sequence Shortening

Formyl-MLFK

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. He HQ, et al. Structural determinants for the interaction of formyl peptide receptor 2 with peptide ligands. J Biol Chem. 2014 Jan 24;289(4):2295-306.

N-Formyl-Met-Leu-Phe(Synonyms: fMLP N-Formyl-MLF)

N-Formyl-Met-Leu-Phe;(Synonyms: fMLP; N-Formyl-MLF) 纯度: 99.81%

N-Formyl-Met-Leu-Phe (fMLP; N-Formyl-MLF) 是一种趋化肽和N-甲酰基肽受体 (FPR) 的特异性配体。报道显示N-Formyl-Met-Leu-Ph 可抑制 TNF-alpha 的分泌。

N-Formyl-Met-Leu-Pheamp;;(Synonyms: fMLP;  N-Formyl-MLF)

N-Formyl-Met-Leu-Phe Chemical Structure

CAS No. : 59880-97-6

规格 价格 是否有货 数量
5 mg ¥500 In-stock
10 mg ¥900 In-stock
50 mg ¥1900 In-stock
100 mg ; 询价 ;
200 mg ; 询价 ;

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N-Formyl-Met-Leu-Phe 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptidomimetic Library
  • Peptide Library

生物活性

N-Formyl-Met-Leu-Phe (fMLP; N-Formyl-MLF) is a chemotactic peptide and a specific ligand of N-formyl peptide receptor (FPR). N-Formyl-Met-Leu-Ph is reported to inhibit TNF-alpha secretion.

IC50 Target

TNF-alpha[1]

体外研究
(In Vitro)

Binding of N-Formyl-Met-Leu-Phe to its specific cell surface receptor, N-formyl peptide receptor (FPR), triggers different cascades of biochemical events, eventually leading to cellular activation. FPR is a chemoattractant receptor belonging to the G protein-coupled receptor family. N-Formyl-Met-Leu-Phe promotes osteoblastic commitment and suppresses adipogenic commitment under osteoblastic differentiation conditions. N-Formyl-Met-Leu-Phe stimulates osteogenesis is associated with increased expression of osteogenic markers and mineralization. N-Formyl-Met-Leu-Phe inhibits expression of peroxisome proliferator-activated receptor-γ1. N-Formyl-Met-Leu-Phe-stimulated osteogenic differentiation is mediated via FPR1-phospholipase C/phospholipase D-Ca2+-calmodulin-dependent kinase II-ERK-CREB signaling pathways[1]. N-Formyl-Met-Leu-Phe, a bacterial-derived peptide, induced proinflammatory cytokine gene expression in human peripheral blood monocytes. Bacterial products LPS and N-Formyl-Met-Leu-Phe synergistically induce inflammatory response via multiple signaling pathways. TLR4, IKKβ-IκBα, and NF-κB signaling pathways are involved in the synergistic induction of TNF-α via p65 nuclear translocation-dependent mechanisms[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

N-Formyl-Met-Leu-Phe promotes bone formation in zebrafish and rabbits. Extensive skeletal development is evident at 5 dpf in over 80% of N-Formyl-Met-Leu-Phe-treated zebrafish. Treatment with N-Formyl-Met-Leu-Phe results in increased expression of Runx2. Bone marrow spaces are widely formed, and connective tissue covering bone is dense, like periosteum, in N-Formyl-Met-Leu-Phe-treated calvaria[1]. N-Formyl-Met-Leu-Phe mediate release of calprotectin from PMN in vitro. It induces release of calprotectin from PMN in a dose dependent manner. A minimum of 10% of total PMN calprotectin is retained at concentrations of 0.1-10.0 nM of N-Formyl-Met-Leu-Phe[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

437.55

Formula

C21H31N3O5S

CAS 号

59880-97-6

Sequence

Formyl-Met-Leu-Phe

Sequence Shortening

Formyl-MLF

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -80deg;C 2 years
-20deg;C 1 year
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

DMSO : ≥ 82.5 mg/mL (188.55 mM)

H2O : < 0.1 mg/mL (ultrasonic) (insoluble)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.2855 mL 11.4273 mL 22.8545 mL
5 mM 0.4571 mL 2.2855 mL 4.5709 mL
10 mM 0.2285 mL 1.1427 mL 2.2855 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂:;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.08 mg/mL (4.75 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (4.75 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂:;10% DMSO ;; 90% corn oil

    Solubility: ≥ 2.08 mg/mL (4.75 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (4.75 mM,饱和度未知) 的澄清溶液,此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例,取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中,混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。
参考文献
  • [1]. Shin MK, et al. N-formyl-methionyl-leucyl-phenylalanine (fMLP) promotes osteoblast differentiation via the N-formyl peptide receptor 1-mediated signaling pathway in human mesenchymal stem cells from bone marrow. J Biol Chem. 2011 May 13;286(19):17133-43.

    [2]. Chen LY, et al. Synergistic induction of inflammation by bacterial products lipopolysaccharide and fMLP: an important microbial pathogenic mechanism. J Immunol. 2009 Feb 15;182(4):2518-24.

    [3]. Hetland G, et al. Chemotaxins C5a and fMLP induce release of calprotectin (leucocyte L1 protein) from polymorphonuclear cells in vitro. Mol Pathol. 1998 Jun;51(3):143-8.

Cell Assay
[2]

Cells are cotransfected with either a dominant negative form of IκBα or a dominant negative form of IKKβ together with the NF-κB-dependent luciferase reporter plasmid. The plasmid pCMVβ is used as a control for transfection efficiency and this is monitored via the expression of β-galactosidase. Cells are transiently transfected with plasmids using DEAE-dextran. The transfected cells are cultivated for 48 h before a 6-h incubation in medium ±N-Formyl-Met-Leu-Phe, LPS, or N-Formyl-Met-Leu-Phe/LPS. Luciferase activity is determined by using the luciferase assay kit and a Monolight 3010 luminometer[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Administration
[2]

Mice: N-Formyl-Met-Leu-Phe is prepared in sterile PBS. Under the anesthesia, mice are intranasally treated with LPS (0.3 mg/kg) or N-Formyl-Met-Leu-Phe (0.5 mg/kg) or N-Formyl-Met-Leu-Phe and LPS in 50 μL of sterile PBS (control), BAL is performed by cannulating the trachea with sterilized PBS, and cells from BAL fluid are stained with Wright-Giemsa stain after cytocentrifuge. For TNF-α protein release, BAL fluid is collected and secreted TNF-α is measured by ELISA as described above[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献
  • [1]. Shin MK, et al. N-formyl-methionyl-leucyl-phenylalanine (fMLP) promotes osteoblast differentiation via the N-formyl peptide receptor 1-mediated signaling pathway in human mesenchymal stem cells from bone marrow. J Biol Chem. 2011 May 13;286(19):17133-43.

    [2]. Chen LY, et al. Synergistic induction of inflammation by bacterial products lipopolysaccharide and fMLP: an important microbial pathogenic mechanism. J Immunol. 2009 Feb 15;182(4):2518-24.

    [3]. Hetland G, et al. Chemotaxins C5a and fMLP induce release of calprotectin (leucocyte L1 protein) from polymorphonuclear cells in vitro. Mol Pathol. 1998 Jun;51(3):143-8.

Tyr-Gly-Gly-Phe-Met-OH(Synonyms: 蛋氨酸脑啡肽 Met-Enkephalin Methionine enkephalin)

Tyr-Gly-Gly-Phe-Met-OH;(Synonyms: 蛋氨酸脑啡肽; Met-Enkephalin; Methionine enkephalin) 纯度: 98.07%

Tyr-Gly-Gly-Phe-Met-OH 通过结合阿片样物质受体 (opioid receptor),可调控人类免疫功能,抑制肿瘤生长。

Tyr-Gly-Gly-Phe-Met-OHamp;;(Synonyms: 蛋氨酸脑啡肽; Met-Enkephalin;  Methionine enkephalin)

Tyr-Gly-Gly-Phe-Met-OH Chemical Structure

CAS No. : 58569-55-4

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg) ; Apply now ;
10;mM;*;1 mL in Water ¥550 In-stock
10 mg ¥500 In-stock
25 mg ¥950 In-stock
50 mg ¥1600 In-stock
100 mg ¥2600 In-stock
200 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

Tyr-Gly-Gly-Phe-Met-OH 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • GPCR/G Protein Compound Library
  • Neuronal Signaling Compound Library
  • Anti-Cancer Compound Library
  • Peptidomimetic Library
  • Neurotransmitter Receptor Compound Library
  • Rare Diseases Drug Library
  • Peptide Library

生物活性

Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.

IC50 Target

Opioid Receptor[1].

体外研究
(In Vitro)

Methionine enkephalin (MENK), an endogenous neuropeptide has a crucial role in both neuroendocrine and immune systems. MENK is believed to have an immunoregulatory activity to have cancer biotherapy activity by binding to the opioid receptors on immune and cancer cells. MENK may also change the tumor microenvironment by binding to opioid receptor on or in cancer cells. All of these mechanisms of action have biologic significance and potential for use in cancer immunotherapy. Furthermore, they reveal a relationship between the endocrine and immune systems[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

573.66

Formula

C27H35N5O7S

CAS 号

58569-55-4

Sequence

Tyr-Gly-Gly-Phe-Met

Sequence Shortening

YGGFM

中文名称

蛋氨酸脑啡肽

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -80deg;C 2 years
-20deg;C 1 year
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

DMSO : ≥ 40 mg/mL (69.73 mM)

H2O : 6.67 mg/mL (11.63 mM; Need ultrasonic)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.7432 mL 8.7160 mL 17.4319 mL
5 mM 0.3486 mL 1.7432 mL 3.4864 mL
10 mM 0.1743 mL 0.8716 mL 1.7432 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Zhao D, et al. Methionine enkephalin, its role in immunoregulation and cancer therapy. Int Immunopharmacol. 2016 Feb 23. pii: S1567-5769(16)30050-9.

[Sar9,Met(O2)11]-Substance P TFA

[Sar9,Met(O2)11]-Substance P TFA; 纯度: 99.68%

[Sar9,Met(O2)11]-Substance P TFA 是一种选择性的速激肽 NK1 受体激动剂。

[Sar9,Met(O2)11]-Substance P TFAamp;;

[Sar9,Met(O2)11]-Substance P TFA Chemical Structure

规格 价格 是否有货 数量
1 mg ¥990 In-stock
5 mg ¥3900 In-stock
10 mg ¥6900 In-stock
25 mg ¥14000 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

* Please select Quantity before adding items.

[Sar9,Met(O2)11]-Substance P TFA 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

[Sar9,Met(O2)11]-Substance P TFA is a tachykinin NK1 receptor selective agonist.

IC50 Target

NK1 receptor[1]

体外研究
(In Vitro)

[Sar9,Met(O2)11]-Substance P and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P is the sole to produce grooming[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1507.68

Formula

C66H101N18F3O17S

Sequence

Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-{Sar}-Leu-Met[O2]-NH2

Sequence Shortening

RPKPQQFF-{Sar}-LM[O2]-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro:;

H2O : 100 mg/mL (66.33 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.6633 mL 3.3164 mL 6.6327 mL
5 mM 0.1327 mL 0.6633 mL 1.3265 mL
10 mM 0.0663 mL 0.3316 mL 0.6633 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Cellier E, et al. Characterization of central and peripheral effects of septide with the use of five tachykinin NK1 receptor antagonists in the rat. Br J Pharmacol. 1999 Jun;127(3):717-28.