Orexin B, human TFA;(Synonyms: Human orexin B TFA) 纯度: 98.08%
Orexin B, human (TFA) 是 Orexin 受体的内源性激动剂,与OX1和OX2结合的 Ki 值分别为 420 和 36 nM。
Orexin B, human TFA Chemical Structure
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
500 μg | ¥2200 | In-stock | |
1 mg | ¥3400 | In-stock | |
5 mg | ¥13000 | In-stock | |
10 mg | ; | 询价 | ; |
50 mg | ; | 询价 | ; |
* Please select Quantity before adding items.
生物活性 |
Orexin B, human (TFA) is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively. |
IC50 Target |
Ki: 420 nM (OX1), 36 nM (OX2)[1]. |
||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
体外研究 (In Vitro) |
Orexin B is derived by proteolytic amino acid precursor, prepro-orexin, which is encoded by a gene localized to chromosome 17q21 in humans. In radioligand binding studies, Orexin B has a higher affinity for the OX2 receptor[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
||||||||||||||||||||
体内研究 (In Vivo) |
Human Orexin B significantly augments food intake; at the 2 hr time point, 5- and 12-fold stimulation of food consumption is observed by 3 nM and 30 nM orexin-B, respectively[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
|
||||||||||||||||||||
分子量 |
3013.36 |
||||||||||||||||||||
Formula |
C123H212N44O35S.C2HF3O2 |
||||||||||||||||||||
Sequence |
Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2 |
||||||||||||||||||||
Sequence Shortening |
RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2 |
||||||||||||||||||||
运输条件 |
Room temperature in continental US; may vary elsewhere. |
||||||||||||||||||||
储存方式 |
Sealed storage, away from moisture
*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture) |
||||||||||||||||||||
Solvent Solubility |
In Vitro:;
H2O Peptide Solubility and Storage Guidelines: 1.;;Calculate the length of the peptide. 2.;;Calculate the overall charge of the entire peptide according to the following table:
3.;;Recommended solution:
|
||||||||||||||||||||
参考文献 |
|