天然产物 黄酮类 Flavonoids
Loureirin A (Synonyms: 龙血素 A) 纯度: 99.92%
Loureirin A 是从龙血树中分离到的黄酮类物质,能够降低 Akt 的磷酸化,具有抗血小板聚集的作用。
Loureirin A Chemical Structure
CAS No. : 119425-89-7
规格 | 价格 | 是否有货 | 数量 |
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10 mM * 1 mL in DMSO | ¥2145 | In-stock | |
5 mg | ¥1950 | In-stock | |
10 mg | 询价 | ||
50 mg | 询价 |
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Loureirin A 相关产品
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生物活性 |
Loureirin A is a flavonoid extracted from Dragon’s Blood, can inhibit Akt phosphorylation, and has antiplatelet activity. |
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IC50 & Target[1] |
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体外研究 (In Vitro) |
Loureirin A (50 μM, 100 μM) inhibits collagen-induced platelet ATP secretion and thrombin-stimulated P-selectin expression in a dose-dependent manner. Loureirin A also significantly impairs platelet spreading on immobilized fibrinogen. Loureirin A almost completely eliminates collagen-induced Akt phosphorylation at Ser473 at the dose of 100 μM, and has an additive inhibitory effect with the phosphoinositide 3-kinase (PI3K) inhibitor Ly294002 on collage-induced Akt phosphorylation in platelets at 50 μM[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
286.32 |
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Formula |
C17H18O4 |
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CAS 号 |
119425-89-7 |
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中文名称 |
龙血素 A |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : ≥ 86.6 mg/mL (302.46 mM) * “≥” means soluble, but saturation unknown. 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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