Quinupristin mesylate(Synonyms: 奎奴普丁甲磺酸)

发表于由

Quinupristin mesylate;(Synonyms: 奎奴普丁甲磺酸)

Quinupristin mesylate 是一种链球菌素类抗生素。Quinupristin mesylate 可阻断细菌核糖体亚基中肽键的合成，阻止多肽链的延伸，促进不完全蛋白链的分离。

Quinupristin mesylateamp;;(Synonyms: 奎奴普丁甲磺酸)

Quinupristin mesylate Chemical Structure

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生物活性

Quinupristin mesylate is a streptogramin antibiotic. Quinupristin mesylate blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits[1][2].

体外研究
(In Vitro)

Quinupristin/dalfopristin is a combination of streptogramin antibiotics used to against infections[1].
Quinupristin/dalfopristin is reportedly effective against Mycoplasma spp.[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1118.32

Formula

C54H71N9O13S2
Sequence Shortening

T-Abu-PF-Pip-Phg (Lactone:Thr1-Phg6)
中文名称

奎奴普丁甲磺酸；达福普丁甲磺酸；喹努普丁甲磺酸
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Gurk-Turner C. Quinupristin/dalfopristin: the first available macrolide-lincosamide-streptogramin antibiotic. Proc (Bayl Univ Med Cent). 2000 Jan;13(1):83-6.

    [2]. Tantibhedhyangkul W, et al. Anti-Mycoplasma Activity of Daptomycin and Its Use for Mycoplasma Elimination in Cell Cultures of Rickettsiae. Antibiotics (Basel). 2019 Aug 21;8(3).