Cyclo(RADfK)

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Cyclo(RADfK); 纯度: 98.03%

Cyclo(RADfK) 是选择性 α(v)β(3) 整合素配体, 广泛用于新血管生成的相关研究。

Cyclo(RADfK)amp;;

Cyclo(RADfK) Chemical Structure

CAS No. : 756500-23-9

规格 价格 是否有货 数量
1 mg ￥1000 In-stock
5 mg ; 询价 ;
10 mg ; 询价 ;

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Cyclo(RADfK) 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Macrocyclic Compound Library
  • Peptide Library

生物活性

Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis.

IC50 Target

Integrin[1].
体外研究
(In Vitro)

Cyclo(RADfK) is a negative control for the cyclo (-RGDfK-), the RGD peptide. RGD peptides are modulators of cell adhesion and are recognized by several members of the integrin family[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

617.70

Formula

C28H43N9O7
CAS 号

756500-23-9
Sequence Shortening

Cyclo(ADFKR)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -80deg;C 2 years
-20deg;C 1 year
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

H2O : 100 mg/mL (161.89 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.6189 mL 8.0945 mL 16.1891 mL
5 mM 0.3238 mL 1.6189 mL 3.2378 mL
10 mM 0.1619 mL 0.8095 mL 1.6189 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Srivatsan A, et al. Conjugation of cRGD peptide to chlorophyll a based photosensitizer (HPPH) alters its pharmacokinetics withenhanced tumor-imaging and photosensitizing (PDT) efficacy. Mol Pharm. 2011 Aug 1;8(4):1186-1197.