HKOH-1

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HKOH-1; 纯度: 98.17%

HKOH-1 是高灵敏度和选择性的荧光探针，可用于检测内源性羟基自由基。

HKOH-1amp;;

HKOH-1 Chemical Structure

CAS No. : 2031170-96-2

规格 价格 是否有货 数量
1 mg ￥3000 In-stock
5 mg ￥9000 In-stock
10 mg ￥15500 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

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HKOH-1 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus

生物活性

HKOH-1 is a highly sensitive and selective fluorescent probe for detecting endogenous hydroxyl radicals[1].

体外研究
(In Vitro)

HKOH-1 shows absorption peaks at 500 nm. In absence of •OH, HKOH-1 is non-fluorescent[1].
HKOH-1r (0.1-50 μM; 24 h) shows negligible or no cytotoxicity in both RAW264.7 cells and Hela cells[1].
HKOH-1r (5 μM; 30 min) detects endogenous •OH in the flow cytometry platform in RAW264.7 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

745.08

Formula

C26H12Cl2I2O6
CAS 号

2031170-96-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4deg;C, sealed storage, away from moisture and light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)
溶解性数据
In Vitro:;

DMSO : 180 mg/mL (241.58 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.3421 mL 6.7107 mL 13.4214 mL
5 mM 0.2684 mL 1.3421 mL 2.6843 mL
10 mM 0.1342 mL 0.6711 mL 1.3421 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Xiaoyu Bai, et al. HKOH-1: A Highly Sensitive and Selective Fluorescent Probe for Detecting Endogenous Hydroxyl Radicals in Living Cells. Angew Chem Int Ed Engl. 2017 Oct 9;56(42):12873-12877.