天然产物 糖类和糖苷 Saccharides and Glycosides
Swertiajaponin;(Synonyms: 日当药黄素)
Swertiajaponin 是一种酪氨酸酶抑制剂，与酪氨酸酶结合囊形成多个氢键和疏水相互作用，IC50 值为 43.47 μM。Swertiajaponin 还能通过抑制氧化应激介导的 MAPK/MITF 信号导致酪氨酸酶蛋白水平下降。Swertiajaponin 能抑制黑色素积累，具有较强的抗氧化活性。
Swertiajaponin Chemical Structure
CAS No. : 6980-25-2
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 1 mg | ￥2290 | In-stock | |
| 5 mg | ￥6860 | In-stock | |
| 10 mg | ; | 询价 | ; |
| 50 mg | ; | 询价 | ; |
* Please select Quantity before adding items.
Swertiajaponin 相关产品
bull;相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
| 生物活性 |
Swertiajaponin is a tyrosinase inhibitor, forms multiple hydrogen bonds and hydrophobic interactions with the binding pocket of tyrosinase, with an IC50 of 43.47 μM. Swertiajaponin also inhibits oxidative stress-mediated MAPK/MITF signaling, leading to decrease in tyrosinase protein level. Swertiajaponin suppresses melanin accumulation and exhibits strong anti-oxidative activity[1]. |
IC50 Target |
IC50: 43.47 μM (tyrosinase)[1] |
|---|---|
| 分子量 |
462.40 |
| Formula |
C22H22O11 |
| CAS 号 |
6980-25-2 |
| 中文名称 |
日当药黄素 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
4deg;C, protect from light *In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light) |
| 参考文献 |
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