Luteolin-7-rutinoside

天然产物 糖类和糖苷 Saccharides and Glycosides

Luteolin-7-rutinoside;

Luteolin-7-rutinoside 具有抗关节炎和抗真菌的双重作用,可用于研究白色念珠菌感染引起的真菌关节炎。

Luteolin-7-rutinoside

Luteolin-7-rutinoside Chemical Structure

CAS No. : 20633-84-5

规格 价格 是否有货
1 mg ¥3000 询问价格 货期
5 mg ¥6500 询问价格 货期
10 mg ¥9800 询问价格 货期

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生物活性

Luteolin-7-rutinoside has both anti-arthritic and antifungal activities, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.

体外研究
(In Vitro)

At a dose of 10 μg Luteolin-7-rutinoside (lonicerin)/mL, there is an approximately 47% decrease of the proliferation as compared to proliferation of Luteolin-7-rutinoside treated (control) T cells (p<0.05). Luteolin-7-rutinoside at 40 μg/mL dose give almost the same rate of T cell proliferation as does 20 μg/mL dose of Luteolin-7-rutinoside. The suppressive activity is dose dependent. Luteolin-7-rutinoside treatment swifts Th1-Th2 balance away from Th1-toward Th2-type responses. Luteolin-7-rutinoside inhibits nitric oxide (NO) production from macrophages[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

594.52

Formula

C27H30O15

CAS 号

20633-84-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
参考文献
  • [1]. Lee JH, et al. Antiarthritic effect of lonicerin on Candida albicans arthritis in mice. Arch Pharm Res. 2011 May;34(5):853-9.