天然产物 糖类和糖苷 Saccharides and Glycosides
Oxypaeoniflorin (Synonyms: 氧化芍药苷)
Oxypaeoniflorin 是一种抗氧化剂,是从 Paeoniae 中分离得到的单萜糖苷化合物。Oxypaeoniflorin 具有神经保护和抗炎作用。
Oxypaeoniflorin Chemical Structure
CAS No. : 39011-91-1
规格 | 价格 | 是否有货 | 数量 |
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10 mM * 1 mL in DMSO | ¥1815 | In-stock | |
5 mg | ¥1650 | In-stock | |
10 mg | ¥2880 | In-stock | |
50 mg | 询价 | ||
100 mg | 询价 |
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Oxypaeoniflorin 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Immunology/Inflammation Compound Library
- Natural Product Library
- Glycoside Compound Library
- Terpenoids Library
- Phenols Library
- Orally Active Compound Library
- Traditional Chinese Medicine Monomer Library
- Neuroprotective Compound Library
生物活性 |
Oxypaeoniflorin, an anti-oxidant, is a monoterpene glycoside compound isolated from Paeoniae species. Oxypaeoniflorin has neuroprotective and anti-inflammatory effects[1][2]. |
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体外研究 (In Vitro) |
Oxypaeoniflorin (OPA; 0.1-10 µM; 8 hours) obviously reversed the hypoxia/reoxygenation (H/R)-induced decrease in cell activity and increase in apoptosis of H9c2 cells. Oxypaeoniflorin inhibits apoptosis by activating the Sirt1 (silent information regulator factor 2 related enzyme 1)/Foxo1(forkhead transcription factor FKHR) signaling pathway in myocardial tissues and H9c2 cells[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
Oxypaeoniflorin (OPA; 10-40 mg/kg; intragastrical administration; every day; for 30 days) treatment significantly reduces disruption of cardiac function and improves the indicators of ejection fraction (EF) and fractional shortening (FS). Oxypaeoniflorin significantly reduces the release of myocardial infarction-related factors, such as the creatine kinase (CK-MB), cardiac troponin I (cTnI) and cardiac troponin T (cTnT)[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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分子量 |
496.46 |
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Formula |
C23H28O12 |
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CAS 号 |
39011-91-1 |
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中文名称 |
氧化芍药苷;羟基芍药苷 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (201.43 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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