天然产物 天然产物苯丙素类 Phenylpropanoids
Biliatresone 纯度: 99.48%
Biliatresone 是一种从球藻 Dysphania glomulifera 和 D. littoralis 中分离出来的天然毒素。Biliatresone 是一种 1,2-二芳基-2-丙酮类异黄酮,在斑马鱼模型中会产生肝外胆道闭锁。
Biliatresone Chemical Structure
CAS No. : 1801433-90-8
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥3800 | In-stock | |
10 mg | ¥6000 | In-stock | |
25 mg | ¥11500 | In-stock | |
50 mg | ¥18000 | In-stock | |
100 mg | 询价 | ||
200 mg | 询价 |
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Biliatresone 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Natural Product Library
生物活性 |
Biliatresone is a natural toxin isolated from Dysphania glomulifera and D. littoralis. Biliatresone, a 1,2-diaryl-2-propenone class of isoflavonoid, produces extrahepatic biliary atresia in a zebrafish model[1]. |
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体外研究 (In Vitro) |
Biliatresone has a reduction in primary cilia and a dose-dependent decrease in visible microtubules, suggesting that Biliatresone decreases microtubule stability in primary neonatal mouse extrahepatic cholangiocytes[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
Biliatresone exhibits toxicity at doses of 0.065-1.0 μg/mL with a marked reduction and the lethal dose of Biliatresone in a zebrafish assay is 1 μg/mL[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
328.32 |
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Formula |
C18H16O6 |
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CAS 号 |
1801433-90-8 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
-80°C, stored under nitrogen |
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溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (304.58 mM; Need ultrasonic) H2O : 12.5 mg/mL (38.07 mM; ultrasonic and warming and heat to 60°C) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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