Velutin

发表于由

天然产物 黄酮类 Flavonoids

Velutin  纯度: ≥98.0%

Velutin 是从槲寄生中提取的苷元，具有抑制黑色素生物合成的活性。Velutin 能通过 NF-κB 途径减少破骨细胞分化和下调 HIF-1α。

Velutin

Velutin Chemical Structure

CAS No. : 25739-41-7

规格 价格 是否有货 数量
5 mg ￥4030 In-stock
10 mg ￥6860 In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Velutin 相关产品

•相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Immunology/Inflammation Compound Library
  • NF-κB Signaling Compound Library
  • Natural Product Library
  • Phenols Library
  • Flavonoids Library

生物活性

Velutin is an aglycone extracted from Korean Mistletoe, with inhibitory activity against melanin biosynthesis. Velutin reduces osteoclast differentiation and down-regulates HIF-1α through the NF-κB pathway[1][2].

分子量

314.29

Formula

C17H14O6
CAS 号

25739-41-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶解性数据
In Vitro: 

DMSO : 50 mg/mL (159.09 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.1818 mL 15.9089 mL 31.8177 mL
5 mM 0.6364 mL 3.1818 mL 6.3635 mL
10 mM 0.3182 mL 1.5909 mL 3.1818 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Jung SH, et al. Velutin, an Aglycone Extracted from Korean Mistletoe, with Improved Inhibitory Activity against Melanin Biosynthesis. Molecules. 2019 Jul 12;24(14).

    [2]. Brito C, et al. Cytotoxicity and potential anti-inflammatory activity of velutin on RAW 264.7 cell line differentiation: Implications in periodontal bone loss. Arch Oral Biol. 2017 Nov;83:348-356