天然产物 黄酮类 Flavonoids
8-Prenylnaringenin (Synonyms: 8-异戊烯基柚皮素) 纯度: 99.30%
8-prenylnaringenin 是一种从啤酒花穗 (Humulus lupulus) 中分离到的异戊烯类黄酮,具有细胞毒性。8-prenylnaringenin 能通过诱导内源性、外源性通路介导的凋亡,对 HCT-116 结肠癌细胞产生抗增殖活性。8-Prenylnaringenin 能通过激活小鼠 Akt 磷酸化途径,促进其从静止诱导的停用性肌肉萎缩中恢复。
8-Prenylnaringenin Chemical Structure
CAS No. : 53846-50-7
规格 | 价格 | 是否有货 | 数量 |
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1 mg | ¥2500 | In-stock | |
5 mg | ¥7200 | In-stock | |
10 mg | 询价 | ||
50 mg | 询价 |
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8-Prenylnaringenin 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
生物活性 |
8-prenylnaringenin is a prenylflavonoid isolated from hop cones (Humulus lupulus), with cytotoxicity. 8-prenylnaringenin has anti-proliferative activity against HCT-116 colon cancer cells via induction of intrinsic and extrinsic pathway-mediated apoptosis. 8-Prenylnaringenin also promotes recovery from immobilization-induced disuse muscle atrophy through activation of the Akt phosphorylation pathway in mice[1] [2] [3]. |
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分子量 |
340.37 |
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Formula |
C20H20O5 |
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CAS 号 |
53846-50-7 |
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中文名称 |
8-异戊烯基柚皮素 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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溶解性数据 |
In Vitro:
DMSO : 250 mg/mL (734.49 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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